Name : polA (CDR20291_0964) Accession : YP_003217463.1 Strain : Clostridium difficile R20291 Genome accession: NC_013316 Putative virulence/resistance : Unknown Product : DNA polymerase I Function : - COG functional category : L : Replication, recombination and repair COG ID : COG0749 EC number : - Position : 1182350 - 1184998 bp Length : 2649 bp Strand : + Note : has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair DNA sequence : TTGGAAAAAAAATTAATTATAATAGATGGAAATTCAATAATAAACAGAGCCTTTTATGCTCTGCCAGAAATGAATAATAA AGAAGGGTTAAAGACCAATGCAATATATGGATTTACAACAATGCTATTTAAAATGATAGATATATATAAACCAACACATA TAAGTGTAGCCTTTGACAGAAAAGCACCTACATTTAGACATTTAGAATATAAAGAGTATAAGGCTGGAAGAAAGGGAATG CCAGATGAACTGGCAGAACAATTACAGCCATTAAAAGACCTTTTAGATAAATTCAAAATAAATAGATTGGAAATAGATGG GTATGAGGCAGACGACATTATAGGAACTGTTTCTAAAAAAGCAGAAAATAATGGGTATAAGGTATACATAGTAACTGGAG ACAAAGATGCTATTCAACTTGCTTCAGATAATACAACTACTCTTATAACAAAAAAAGGAGTTGGAGAAGTTGAAGAATAC AACTTTAATTCTGTAATTGAAAAATACGAGATGACTCCAGCACAATTTATTGATTTAAAAGGTCTTATGGGAGATAAGTC AGATAATATACCTGGAGTACCTGGAATCGGTGAAAAAACAGGTATAAAGCTTATAAAAGAGTTTTCTAGTATAGAGAATT TAATAGAGAATACAGATAAGCTTAAAGGTAGTGTAAAAAAGAAAATAGAGGAAAATAAAGAAATAGCTATTCAAAGTAAA AGACTTGCAACAATTATAAGAGATGTGCCAATAGAAGTGGATTTAGATAGTATGGTTTTTGGCGATTATGATAAAGATGA ACTTTTAGATAAATTTAGATACTTTGGATTTACAAGTCTCTTATCAAGATTAGTTGATTTGGTCGATTCAGATGACACAG AACACGTAGAAGAAAAAATAGAAATATTAAAATTAAAAGATACAGAAAAATTTATAGATGAAGTAAACAAAAAAGGACAA GTTATTTTAAAAACTGTTAGAGGACAAGGTAATATACTTGAAAAAAATATAATATATATTTTTATAAGTGTAGATGGAGA AAAAATATATTATGTAGATTCAAATGAAGTGTCAAAGTTAGATAGTATATTTTCAAATAATGAAATTAAAAAGTATGGAT ATAATTTAAAAGATGATTATATATCTTTAAAACCATATAATATAAACTTAGAAAATATGTATTTTGATATAACAATAGCT GAGTACTTAATAGATTCAACTTCATCTACCTCATATGATTGTAGTGCAATAGCTATGAAGTATTTATCAAAAAAGGTTAA ATCAAAAGAAGAATTATTAGGAAAGGGTGTTAAATCTAAAAACTATGAGGATTTAGAATTTGAGGATTTAGCAGAGTATA TGGGTCAAATAATATGCACAGTTAAAGAAACAATTCCTATGATGGAAAGAAGTCTAATGGATATGAGTATGGATGGTCTT TTTTATCATGTAGAGATGCCTTTAGTAGAAGTCTTAGGTCATATGGAGTATGAAGGTATAAAAGTAGACAAAAGTATATT GGATGAATTGAGTGTAGAGTTTAAAGAAATAATAGCTACACTAGAAAAGGAAATTTATGAATTATCAGGAGAGCCATTCA ATATAAATTCACCAAAACAATTGGGTGTTATATTATTTGAAAAATTAGAGCTTCCAATAATTAAAAAAACTAAAACTGGA TATTCAACTAATGCAGATGTTTTAGAAAAATTAAGAGATAAGCATCCAATAATAGATAAGATAACTGAGTATAGACAAAT AGTAAAGTTAAATTCTACTTACGTTGAAGGACTTTTAAATATAATAAATCCAGAAAGTAATAGAATACATTCATCATTTA ATCAAACTATAACGACTACAGGAAGAATTTCATCTACAGAACCAAATCTTCAAAATATACCTATAAAAATGGAAATGGGT AGAAAAATAAGAAAAGTGTTTATTGCAGATGATAACTGTAAGTTGGTTGATGCCGATTACTCACAAGTAGAGCTAAGAGT TCTTGCACATATGAGTCAGGATGAAAATATGATAGAAGCATTTAAACATCATGAAGATATTCATACCAAAACAGCTTCAC AAGTTTTTAATGTTCCTATGGAAGATGTTACTAGTGAATTGAGAGGTGCAGCTAAAGCTGTAAACTTTGGTATTATATAT GGTAAAAGTGACTTTGGTCTAGCTGATGATTTAAATATACCTGTTCCAAAGGCGAAAGAATATATCGAAAGTTATTTTGC TAAATACCATAAAATAAAAGAGTTTATGGACACAACAGTAGAAAAGGCTAGTGAGGATGGATATGCTGTAACAATTTTAA ACAGAAGAAGATATATACCAGAAATAAAGTCAAGCAATTTTATGGAAAGAAATAGAGGAAAGAGATTTGCAATGAATGCA CCAATACAAGGAAGTGCAGCAGATATAATAAAAATTGCTATGATAAATGTTCATAAAAAATTGGAAGAGAACAATTTGAA ATCAAAACTTATACTACAAGTTCACGACGAGTTGATAGTTGAAGCAATTGATGATGAAATAGATATAGTTAAGAAAATAG TAAAAGAAGAAATGGAAAATGCTGTAAATATGGATGTTCACTTAGATGTAGATTTAAATGTAGGTAGTTCTTGGTATGAG ACAAAGTAG Protein sequence : MEKKLIIIDGNSIINRAFYALPEMNNKEGLKTNAIYGFTTMLFKMIDIYKPTHISVAFDRKAPTFRHLEYKEYKAGRKGM PDELAEQLQPLKDLLDKFKINRLEIDGYEADDIIGTVSKKAENNGYKVYIVTGDKDAIQLASDNTTTLITKKGVGEVEEY NFNSVIEKYEMTPAQFIDLKGLMGDKSDNIPGVPGIGEKTGIKLIKEFSSIENLIENTDKLKGSVKKKIEENKEIAIQSK RLATIIRDVPIEVDLDSMVFGDYDKDELLDKFRYFGFTSLLSRLVDLVDSDDTEHVEEKIEILKLKDTEKFIDEVNKKGQ VILKTVRGQGNILEKNIIYIFISVDGEKIYYVDSNEVSKLDSIFSNNEIKKYGYNLKDDYISLKPYNINLENMYFDITIA EYLIDSTSSTSYDCSAIAMKYLSKKVKSKEELLGKGVKSKNYEDLEFEDLAEYMGQIICTVKETIPMMERSLMDMSMDGL FYHVEMPLVEVLGHMEYEGIKVDKSILDELSVEFKEIIATLEKEIYELSGEPFNINSPKQLGVILFEKLELPIIKKTKTG YSTNADVLEKLRDKHPIIDKITEYRQIVKLNSTYVEGLLNIINPESNRIHSSFNQTITTTGRISSTEPNLQNIPIKMEMG RKIRKVFIADDNCKLVDADYSQVELRVLAHMSQDENMIEAFKHHEDIHTKTASQVFNVPMEDVTSELRGAAKAVNFGIIY GKSDFGLADDLNIPVPKAKEYIESYFAKYHKIKEFMDTTVEKASEDGYAVTILNRRRYIPEIKSSNFMERNRGKRFAMNA PIQGSAADIIKIAMINVHKKLEENNLKSKLILQVHDELIVEAIDDEIDIVKKIVKEEMENAVNMDVHLDVDLNVGSSWYE TK |
Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
polA | YP_281523.1 | DNA polymerase I | Not tested | Not named | Protein | 7e-137 | 43 |