Gene Information

Name : clpC (CD196_0027)
Accession : YP_003213080.1
Strain : Clostridium difficile CD196
Genome accession: NC_013315
Putative virulence/resistance : Virulence
Product : ATP-dependent Clp protease
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 42995 - 45244 bp
Length : 2250 bp
Strand : +
Note : -

DNA sequence :
ATGGAAGGTAAGGGAGAAGAAATCTCAGAAGATATAGTATTAAGTCCAAGGAGTAAACAAATACTTGAATTATCAGGAAT
GTTTGCAAATAAATTAAAAACAAATTATATTGGGACTGAGCATATATTATTAGCAATTATTCAAGAAGGTGAAGGAATAG
CTAATAAGATTTTAAATTATGCTGGAGTAAATGATAGGACTTTAGCCCAATTAACAATTGATATGATGGGTATTAGTGAT
AAAAATCAATACAAAGCAGAGAATAGTTACACGGGCAACCAGAATCAAGCAGAATCTAAAGTACTTGATAAGTATGGAAG
AAATCTTACACTATATGCAAAACAGAATAAAATAGACCCTGTAATAGGTAGAGAAAAAGAAATACAAAGAGTAATACAAA
TATTAAGTAGAAGAACTAAAAACAATCCAGTGTTGATAGGAGACCCAGGTGTAGGGAAAACAGCCATAGCTGAAGGTCTG
GCTACAAATATAGCCTTAGGAAATGTTCCAGAAACACTAAAAAACAAAACTTTATACTCTTTAGAGATGGGTTCATTATT
GGCTGGGGCTAAGTATAGAGGAGAATTTGAAGAAAGAATTAAAGAAGTTGTAGATGAAGTTGTTAAAAATGGAAACATAA
TCTTATTTATAGATGAGATGCACACAATAATAGGGGCTGGGTCTACTGGAGAAGGCTCTATAGATGCTTCAAATATATTA
AAGCCAGCCTTGGCAAGAGGAGAAATACAAGTTATAGGTGCAACTACAATTGATGAATATAGAAAGCATGTTGAAAAAGA
TTCTGCTCTAGAAAGAAGATTCCAACCAGTTATGGTAGATGAACCAACTAAAGAGGACTCAATAAAAATATTAGAAGGAT
TAAGAGATAAATATGAAGCTCATCATAAAGTTAAAATAACTGATGATGCTATAAAGGCAGCTGTAGAATTATCAACTAGA
TATATATCAGACAGATATCTGCCAGATAAAGCTATAGACTTGATTGATGAAGCTGCATCAAAAGTAAGATTAAAAGAAAA
TACACCTCCTTCAGAAATAAAAAAATTAGAACTAGAAATAGAAAATATAGATAAAGAAAAAGAAGAAGCAGTAAGATGTC
AAGACTTTGAGAAAGCAGCCAAAATAAGAGATGAACAAGGTCTACTTAAAAAACAATTAGAAGATGTTAGAGAAAGATGG
AACAAGTCATCTAAACATTCAGATTTAGTTGATGGAGAAGTTATTGCTGAAGTAGTGGGCTTATGGACAGGAATACCAGT
TAATAAAATTCTTGAAGAAGAGGCTGATAGACTTTTGAGACTTGAGGAAATACTGCACAATAGAGTTATAGGTCAAGAAC
AAGCAGTAAAATCTATTTCAAAGGCAATCAGAAGGTCAAGAGCAGGTCTTAAAGACCCTAATAGACCAATTGGTTCATTT
TTATTTTTAGGTCCAACAGGAGTAGGTAAAACAGAATTATCTAAGGCATTAGCAGAAGTGCAATTTGGAGATGAAAATCA
AATAATTAGAATAGATATGTCTGAATATATGGAAAAACATGCTGTGTCAAGAATGATAGGTTCACCTCCAGGTTATGTAG
GTCATGATGAAGGTGGTCAATTAACTGAAAAAGTAAGAAGAAATCCATATTCAGTTATCTTATTTGATGAGATAGAAAAA
GCTCATCCAGATGTATTTAATATTCTGTTACAAATTCTAGATGATGGTAGACTAACTGATTCAAAAGGAAGAACTGTAGA
TTTTAAGAATACTATTGTAATAATGACATCAAATGTTGGAGCATCTACAATTGGTAGACAAAAAACTTTAGGATTTAGTA
TAGCTAAAGGAGACGAAGAAGAAAAATCTCAATATGAAAAAATGAAAGAAAATATAATGGGTGAATTAAAACAAAGATTC
AGACCAGAGTTTTTAAACAGAATAGATGATATAATTGTTTTCCACTCACTAAATGAAAATCATATATCAAAAATAGTACT
TTTAATGGCAGCGAAACTACAAGAGAGATTAAAAGAAATGGATATAAAATTAGAAATGAGTGATGAGGCTGTTAAATTAA
TTTCTAAATCTGGATTTGACTTAGAATATGGAGCAAGACCTCTTAAAAGAGCTTTACAAAAAGAGTTGGAAGATGAGCTA
TCTGAAGCAATCTTAAAAGGTAATGTGAAAAAGGGAAGTAATGTAGTAGCAAAAGTCAAAGATGAAAAAATAGTTTTTGA
AACTAAATAA

Protein sequence :
MEGKGEEISEDIVLSPRSKQILELSGMFANKLKTNYIGTEHILLAIIQEGEGIANKILNYAGVNDRTLAQLTIDMMGISD
KNQYKAENSYTGNQNQAESKVLDKYGRNLTLYAKQNKIDPVIGREKEIQRVIQILSRRTKNNPVLIGDPGVGKTAIAEGL
ATNIALGNVPETLKNKTLYSLEMGSLLAGAKYRGEFEERIKEVVDEVVKNGNIILFIDEMHTIIGAGSTGEGSIDASNIL
KPALARGEIQVIGATTIDEYRKHVEKDSALERRFQPVMVDEPTKEDSIKILEGLRDKYEAHHKVKITDDAIKAAVELSTR
YISDRYLPDKAIDLIDEAASKVRLKENTPPSEIKKLELEIENIDKEKEEAVRCQDFEKAAKIRDEQGLLKKQLEDVRERW
NKSSKHSDLVDGEVIAEVVGLWTGIPVNKILEEEADRLLRLEEILHNRVIGQEQAVKSISKAIRRSRAGLKDPNRPIGSF
LFLGPTGVGKTELSKALAEVQFGDENQIIRIDMSEYMEKHAVSRMIGSPPGYVGHDEGGQLTEKVRRNPYSVILFDEIEK
AHPDVFNILLQILDDGRLTDSKGRTVDFKNTIVIMTSNVGASTIGRQKTLGFSIAKGDEEEKSQYEKMKENIMGELKQRF
RPEFLNRIDDIIVFHSLNENHISKIVLLMAAKLQERLKEMDIKLEMSDEAVKLISKSGFDLEYGARPLKRALQKELEDEL
SEAILKGNVKKGSNVVAKVKDEKIVFETK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 53

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpC YP_003213080.1 ATP-dependent Clp protease VFG0079 Protein 0.0 59
clpC YP_003213080.1 ATP-dependent Clp protease VFG0080 Protein 4e-151 49