Gene Information

Name : purA (CD196_3468)
Accession : YP_003216481.1
Strain : Clostridium difficile CD196
Genome accession: NC_013315
Putative virulence/resistance : Unknown
Product : adenylosuccinate synthetase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0104
EC number : -
Position : 4086491 - 4087780 bp
Length : 1290 bp
Strand : -
Note : catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis

DNA sequence :
ATGAAAACAGTTGCAATTGTTGGTTCTCAATGGGGAGATGAAGGTAAAGGTAAAGTTATAGATTATCTTGCTACTCAAGC
AGATGTAGTAGTAAGAGGGCAAGGTGGAAATAATGCAGGACATACATTAGTTGTAGAAGGTAAAAAATACGCATTACATC
TAATTCCATCTGGAGTTTTAAATCCAAATACAGTGAATATAATCGGAAATGGAATAGTGTTTGACCCTAAAGGATTTTTA
GAAGAATTGGAAATGTTTAAAACGGATAATATAAGTACAGAAAATATAAAAATAAGTGATAGAGCACATGTCATATTCCC
ATATCATAAAGAACTAGATGCATTGTCAGAAGAAGCCAGAGGCGATTTAAAGATAGGTACAACAAAAAAAGGTATTGGAC
CTTGTTATATGGATAAAACAGAGAGATCTGGTATTAGAATATGTGACTTAATGGATAAAGATAAATTTGCTATAAAATTA
AAAGCTCAAATAGATGCTAAAAATAAAATAGTTAAAAATATATATGGAAAAGAAGAATTATTTGATTTTGAAACTATATA
TAACGAATATCTAGGATATGCAGAACAAATAAGAAAATATGTGGCAGATACGTCTGTTATTGTATATGATGCAGTAAGAG
CAGGTAAAAAAGTATTGTTTGAAGGAGCACAAGGGACTTTATTAGATTTAGATTTAGGAACTTATCCATTTGTTACATCT
TCTCATCCAACATCTGGTGGATTTGCAATTGGTGCAGGTATAGGACCAAATATGATAAAAGACGTTGTTGGTATAGTAAA
AGCATATACTACAAGAGTTGGAGAAGGACCGTTTGTTACAGAGCAAATAAATGAAACTGGAGATAAGATAAGAGAACAAG
GACATGAATTTGGGGTAACTACTGGTAGACCAAGAAGATGTGGGTGGTTTGATGCAGTTATAGTTAAGTATGCAGCTAGA
GTTAATGGATTGACTAGTATTTCATTTATGTTACTTGATGTATTAACTGGATTTGATAAGATAAAAGTTTGTACGTCTTA
TAAAATGGGCGATAAGATAATAACGGATTTCCCAGCTTCATTAGATGATTTAGCAAAATGTGAACCTGTATATGAAGAAT
TAGATGGATGGAATGAAGATATAACTCAAATAGATAACTTTGATGACCTTCCAGAAAATGCAAAGAAATATGTAGCAAAA
ATAGAAGAACTAGTTGGAGTAAGTGTAGATATGGTTTCTGTTGGTCCAAATAGAGCTCAAACTATAATAAGAAGAAATAT
ATTTGCTTAA

Protein sequence :
MKTVAIVGSQWGDEGKGKVIDYLATQADVVVRGQGGNNAGHTLVVEGKKYALHLIPSGVLNPNTVNIIGNGIVFDPKGFL
EELEMFKTDNISTENIKISDRAHVIFPYHKELDALSEEARGDLKIGTTKKGIGPCYMDKTERSGIRICDLMDKDKFAIKL
KAQIDAKNKIVKNIYGKEELFDFETIYNEYLGYAEQIRKYVADTSVIVYDAVRAGKKVLFEGAQGTLLDLDLGTYPFVTS
SHPTSGGFAIGAGIGPNMIKDVVGIVKAYTTRVGEGPFVTEQINETGDKIREQGHEFGVTTGRPRRCGWFDAVIVKYAAR
VNGLTSISFMLLDVLTGFDKIKVCTSYKMGDKIITDFPASLDDLAKCEPVYEELDGWNEDITQIDNFDDLPENAKKYVAK
IEELVGVSVDMVSVGPNRAQTIIRRNIFA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
purA YP_281500.1 adenylosuccinate synthetase Not tested Not named Protein 1e-127 55