Gene Information

Name : fhuC (CD196_2724)
Accession : YP_003215742.1
Strain : Clostridium difficile CD196
Genome accession: NC_013315
Putative virulence/resistance : Virulence
Product : ferrichrome ABC transporter ATP-binding protein
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG1120
EC number : -
Position : 3202334 - 3203116 bp
Length : 783 bp
Strand : -
Note : -

DNA sequence :

ATGAACTGTATAAATACTAAGAATCTAAATGTATCATATGGAAACACAGATATTATAAAAAATTTAAATTTAAATATACC
AAAAGGAAAAATAACTACCATCATAGGGGCTAATGGTTGTGGAAAATCGACAATACTTAAAACTATAGGTAGAATTATTA
GCCCTAATAGTGGGAAAATATATATAAATGGAGAGGACATCTACAAAAAGAAGTCTAAAGAAATAGCAAAGGATATGGCT
GTACTTCCACAAAGCCCTCAAGCTCCTAGTGGTCTTACCGTTTCAGAATTAATTTCTTATGGAAGATTTCCTCATAAAAG
TGGATTTGGTAATTCTAGTAAAGAAGACAGAGAGATTGTAAATTGGAGTTTAGAAGTTACTGGAATTGCAGAATTTAAGG
ATAGAAATATGGAAGATTTATCAGGAGGACAAAGACAAAGGGCATGGATAGCTATGGCTTTGGCACAAGAAACTGATATA
TTATTACTGGATGAGCCTACAACATATTTAGATTTGGCACATCAATTAGAGATACTAAAATTATTAGATGAACTAAATAA
AAAACAAGGAAGAACTATTGTCATGGTAATACATGAACTTAATAATGCAGCAAGATTTGCTGACCACATGATAGGTATTA
AGAAAGGTAAAATAGTTTGTGAAGGTGATGCATATGATGTTATGACGAAGGATAATCTAAAAGAATTATTTAATATTGAT
GCAGAAATAGCAACAGACCCAAGAACAAATAAACCAATTTGTATAACTTATGACATGGTGTAA

Protein sequence :

MNCINTKNLNVSYGNTDIIKNLNLNIPKGKITTIIGANGCGKSTILKTIGRIISPNSGKIYINGEDIYKKKSKEIAKDMA
VLPQSPQAPSGLTVSELISYGRFPHKSGFGNSSKEDREIVNWSLEVTGIAEFKDRNMEDLSGGQRQRAWIAMALAQETDI
LLLDEPTTYLDLAHQLEILKLLDELNKKQGRTIVMVIHELNNAARFADHMIGIKKGKIVCEGDAYDVMTKDNLKELFNID
AEIATDPRTNKPICITYDMV

• Homologs from PAI DB

Gene	GenBank Accn	Product	Virulance or Resistance	PAI or REI	Alignment Type	E-val	Identity
SPN23F_09560	YP_002510939.1	ferric siderophore ABC transporter ATP-binding protein	Virulence	PPI-1	Protein	2e-55	47
SP_1035	NP_345510.1	iron-compound ABC transporter ATP-binding protein	Not tested	PPI-1	Protein	2e-55	47
DIP0585	NP_938961.1	iron ABC transporter ATP-binding protein	Virulence	Not named	Protein	2e-56	45
fagC	YP_005680307.1	ATP binding cytoplasmic membrane protein	Not tested	PiCp 1	Protein	3e-52	45
fagC	YP_003782430.1	ABC transporter ATP-binding protein	Not tested	PiCp 1	Protein	3e-52	45
fagC	YP_005682397.1	ATP binding cytoplasmic membrane protein	Virulence	PiCp 1	Protein	3e-52	45
fagC	YP_005684488.1	ATP binding cytoplasmic membrane protein	Not tested	PiCp 1	Protein	3e-52	45
fecE	AAL08451.1	ATP-binding protein FecE	Virulence	SRL	Protein	4e-55	43
ciuD	YP_005681255.1	Iron ABC transporter ATP-binding protein	Virulence	PiCp 4	Protein	2e-53	43
ciuD	YP_005683346.1	Iron ABC transporter ATP-binding protein	Virulence	PiCp 4	Protein	2e-53	43
ciuD	YP_003783391.1	iron ABC transporter ATP-binding protein	Virulence	PiCp 4	Protein	2e-53	43
ciuD	YP_005685432.1	Iron ABC transporter ATP-binding protein	Virulence	PiCp 4	Protein	2e-53	43
iusE	YP_005143742.1	iron ABC transporter ATP-binding protein	Virulence	Not named	Protein	4e-55	42

• Homologs from CARD and BacMet (resistance genes)

Gene	GenBank Accn	Product	ID of source DB	Alignment Type	E-val	Identity
fhuC	YP_003215742.1	ferrichrome ABC transporter ATP-binding protein	BAC0164	Protein	3e-55	43

• Homologs from VFDB (virulence genes)

Gene	GenBank Accn	Product	ID of source DB	Alignment Type	E-val	Identity
fhuC	YP_003215742.1	ferrichrome ABC transporter ATP-binding protein	VFG1042	Protein	2e-55	43
fhuC	YP_003215742.1	ferrichrome ABC transporter ATP-binding protein	VFG0925	Protein	2e-55	43