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Name : vanG (CD196_1549) Accession : YP_003214576.1 Strain : Clostridium difficile CD196 Genome accession: NC_013315 Putative virulence/resistance : Resistance Product : D-alanine:D-alanine ligase Function : - COG functional category : M : Cell wall/membrane/envelope biogenesis COG ID : COG1181 EC number : - Position : 1800622 - 1801722 bp Length : 1101 bp Strand : + Note : - DNA sequence : ATGAATAATAAAAAAATTGCAGTTATATTTGGTGGAAACTCAACAGAATATGATGTATCATTACAATCAGCTTTTGCAGT ACTTGAGAATTTGAATACGGAAAAATATGATATTATACCAATTGGAATTACAAGGGAGGGTAATTGGTATCATTATATTG GAGATTATAATAATATCCAGAATAACACTTGGTTTGAAAGGGATACTGATATAATTCCAGTTATTGTTTCGCAGAACCGT GTCAAAAATGGTATTATTGAATTTTTAATTCCTGATGCTGTTTCTCAGAATCATATTCCAAATAGTGCTATTGAATCATG TGAAAATGATATTAAATACACTAAACTTGATTTTGTATTTCCTGTATTGCATGGAAAAAATGGAGAAGATGGAACAGTGC AGGGGTTATTTGAATTGGCAGGTATACAGGTTATTGGATGTGGTACTCTTTCTTCAGCATTATGTATGGACAAAGACAAA TCACATAAACTTGTTCATTCAGAAGGTATTAAAGTACCAAAATCAATATTACTAAAATACTCAGATAAATTTAATGTGGC TGAACTGTCAAAAGACTTAACTTATCCATTATTTATAAAACCTGTGCGTGCAGGTTCATCATTTGGTATTAGTAAAATTT ATAAAAAAGAAGAGTTACAAGTAGCAGTAGACTTGGCTTTTGAACATGATAATGAAGTAATAATTGAGGAAAATATTGAT GGTTTTGAGGTAGGGTGTGCAGTTTTAGGAAACGATGACTTACTTGTTGGAAGAGTAGATGAAATAGAATTGTCAAAAGG ATTTTTTGATTATACAGAAAAATATACATTGAAAAGTTCAAAAATTCATATGCCAGCTAGAATTGATTTGGATTGTGAGA AAAGAATACAAGAGACAGCAAAAATTATTTATAGAACTCTTGGATGTTCTGGATTTGCTAGAGTAGATATGTTTTTAACT CCATCTGGTGAAATTATTTTTAATGAAGTCAATACAATTCCTGGCTTTACTTCTCATAGTCGTTATCCGAATATGATGAA AGGTATTGGACTGTCTTTTGAAGAAATATTGGATAAGATAATTGAGGTGTACATAAAATGA Protein sequence : MNNKKIAVIFGGNSTEYDVSLQSAFAVLENLNTEKYDIIPIGITREGNWYHYIGDYNNIQNNTWFERDTDIIPVIVSQNR VKNGIIEFLIPDAVSQNHIPNSAIESCENDIKYTKLDFVFPVLHGKNGEDGTVQGLFELAGIQVIGCGTLSSALCMDKDK SHKLVHSEGIKVPKSILLKYSDKFNVAELSKDLTYPLFIKPVRAGSSFGISKIYKKEELQVAVDLAFEHDNEVIIEENID GFEVGCAVLGNDDLLVGRVDEIELSKGFFDYTEKYTLKSSKIHMPARIDLDCEKRIQETAKIIYRTLGCSGFARVDMFLT PSGEIIFNEVNTIPGFTSHSRYPNMMKGIGLSFEEILDKIIEVYIK |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| vanB | YP_008394259.1 | Vancomycin B-type resistance protein vanB, D-alanine--D-lactate ligase | Not tested | Not named | Protein | 7e-60 | 43 |
| vanB | NP_815951.1 | D-alanine--D-lactate ligase | Not tested | Not named | Protein | 2e-60 | 43 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| vanG | YP_003214576.1 | D-alanine:D-alanine ligase | AF310956.2.orf5.gene | Protein | 4e-61 | 43 |
| vanG | YP_003214576.1 | D-alanine:D-alanine ligase | AY145441.gene.p01 | Protein | 4e-61 | 43 |
| vanG | YP_003214576.1 | D-alanine:D-alanine ligase | U00456.gene.p01 | Protein | 9e-61 | 43 |
| vanG | YP_003214576.1 | D-alanine:D-alanine ligase | U35369.1.gene6.p01 | Protein | 9e-61 | 43 |
| vanG | YP_003214576.1 | D-alanine:D-alanine ligase | AE016830.1.gene2250. | Protein | 9e-61 | 43 |
| vanG | YP_003214576.1 | D-alanine:D-alanine ligase | AF277571.gene.p01 | Protein | 2e-58 | 43 |
| vanG | YP_003214576.1 | D-alanine:D-alanine ligase | AF130997.1.orf4.gene | Protein | 7e-58 | 42 |
| vanG | YP_003214576.1 | D-alanine:D-alanine ligase | AY489045.gene.p01 | Protein | 3e-57 | 42 |
| vanG | YP_003214576.1 | D-alanine:D-alanine ligase | AF162694.gene.p01 | Protein | 2e-65 | 42 |
| vanG | YP_003214576.1 | D-alanine:D-alanine ligase | L29638.gene.p01 | Protein | 1e-60 | 41 |
