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Name : polA (CD196_0986) Accession : YP_003214017.1 Strain : Clostridium difficile CD196 Genome accession: NC_013315 Putative virulence/resistance : Unknown Product : DNA polymerase I Function : - COG functional category : L : Replication, recombination and repair COG ID : COG0749 EC number : - Position : 1184734 - 1187382 bp Length : 2649 bp Strand : + Note : has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair DNA sequence : TTGGAAAAAAAATTAATTATAATAGATGGAAATTCAATAATAAACAGAGCCTTTTATGCTCTGCCAGAAATGAATAATAA AGAAGGGTTAAAGACCAATGCAATATATGGATTTACAACAATGCTATTTAAAATGATAGATATATATAAACCAACACATA TAAGTGTAGCCTTTGACAGAAAAGCACCTACATTTAGACATTTAGAATATAAAGAGTATAAGGCTGGAAGAAAGGGAATG CCAGATGAACTGGCAGAACAATTACAGCCATTAAAAGACCTTTTAGATAAATTCAAAATAAATAGATTGGAAATAGATGG GTATGAGGCAGACGACATTATAGGAACTGTTTCTAAAAAAGCAGAAAATAATGGGTATAAGGTATACATAGTAACTGGAG ACAAAGATGCTATTCAACTTGCTTCAGATAATACAACTACTCTTATAACAAAAAAAGGAGTTGGAGAAGTTGAAGAATAC AACTTTAATTCTGTAATTGAAAAATACGAGATGACTCCAGCACAATTTATTGATTTAAAAGGTCTTATGGGAGATAAGTC AGATAATATACCTGGAGTACCTGGAATCGGTGAAAAAACAGGTATAAAGCTTATAAAAGAGTTTTCTAGTATAGAGAATT TAATAGAGAATACAGATAAGCTTAAAGGTAGTGTAAAAAAGAAAATAGAGGAAAATAAAGAAATAGCTATTCAAAGTAAA AGACTTGCAACAATTATAAGAGATGTGCCAATAGAAGTGGATTTAGATAGTATGGTTTTTGGCGATTATGATAAAGATGA ACTTTTAGATAAATTTAGATACTTTGGATTTACAAGTCTCTTATCAAGATTAGTTGATTTGGTCGATTCAGATGACACAG AACACGTAGAAGAAAAAATAGAAATATTAAAATTAAAAGATACAGAAAAATTTATAGATGAAGTAAACAAAAAAGGACAA GTTATTTTAAAAACTGTTAGAGGACAAGGTAATATACTTGAAAAAAATATAATATATATTTTTATAAGTGTAGATGGAGA AAAAATATATTATGTAGATTCAAATGAAGTGTCAAAGTTAGATAGTATATTTTCAAATAATGAAATTAAAAAGTATGGAT ATAATTTAAAAGATGATTATATATCTTTAAAACCATATAATATAAACTTAGAAAATATGTATTTTGATATAACAATAGCT GAGTACTTAATAGATTCAACTTCATCTACCTCATATGATTGTAGTGCAATAGCTATGAAGTATTTATCAAAAAAGGTTAA ATCAAAAGAAGAATTATTAGGAAAGGGTGTTAAATCTAAAAACTATGAGGATTTAGAATTTGAGGATTTAGCAGAGTATA TGGGTCAAATAATATGCACAGTTAAAGAAACAATTCCTATGATGGAAAGAAGTCTAATGGATATGAGTATGGATGGTCTT TTTTATCATGTAGAGATGCCTTTAGTAGAAGTCTTAGGTCATATGGAGTATGAAGGTATAAAAGTAGACAAAAGTATATT GGATGAATTGAGTGTAGAGTTTAAAGAAATAATAGCTACACTAGAAAAGGAAATTTATGAATTATCAGGAGAGCCATTCA ATATAAATTCACCAAAACAATTGGGTGTTATATTATTTGAAAAATTAGAGCTTCCAATAATTAAAAAAACTAAAACTGGA TATTCAACTAATGCAGATGTTTTAGAAAAATTAAGAGATAAGCATCCAATAATAGATAAGATAACTGAGTATAGACAAAT AGTAAAGTTAAATTCTACTTACGTTGAAGGACTTTTAAATATAATAAATCCAGAAAGTAATAGAATACATTCATCATTTA ATCAAACTATAACGACTACAGGAAGAATTTCATCTACAGAACCAAATCTTCAAAATATACCTATAAAAATGGAAATGGGT AGAAAAATAAGAAAAGTGTTTATTGCAGATGATAACTGTAAGTTGGTTGATGCCGATTACTCACAAGTAGAGCTAAGAGT TCTTGCACATATGAGTCAGGATGAAAATATGATAGAAGCATTTAAACATCATGAAGATATTCATACCAAAACAGCTTCAC AAGTTTTTAATGTTCCTATGGAAGATGTTACTAGTGAATTGAGAGGTGCAGCTAAAGCTGTAAACTTTGGTATTATATAT GGTAAAAGTGACTTTGGTCTAGCTGATGATTTAAATATACCTGTTCCAAAGGCGAAAGAATATATCGAAAGTTATTTTGC TAAATACCATAAAATAAAAGAGTTTATGGACACAACAGTAGAAAAGGCTAGTGAGGATGGATATGCTGTAACAATTTTAA ACAGAAGAAGATATATACCAGAAATAAAGTCAAGCAATTTTATGGAAAGAAATAGAGGAAAGAGATTTGCAATGAATGCA CCAATACAAGGAAGTGCAGCAGATATAATAAAAATTGCTATGATAAATGTTCATAAAAAATTGGAAGAGAACAATTTGAA ATCAAAACTTATACTACAAGTTCACGACGAGTTGATAGTTGAAGCAATTGATGATGAAATAGATATAGTTAAGAAAATAG TAAAAGAAGAAATGGAAAATGCTGTAAATATGGATGTTCACTTAGATGTAGATTTAAATGTAGGTAGTTCTTGGTATGAG ACAAAGTAG Protein sequence : MEKKLIIIDGNSIINRAFYALPEMNNKEGLKTNAIYGFTTMLFKMIDIYKPTHISVAFDRKAPTFRHLEYKEYKAGRKGM PDELAEQLQPLKDLLDKFKINRLEIDGYEADDIIGTVSKKAENNGYKVYIVTGDKDAIQLASDNTTTLITKKGVGEVEEY NFNSVIEKYEMTPAQFIDLKGLMGDKSDNIPGVPGIGEKTGIKLIKEFSSIENLIENTDKLKGSVKKKIEENKEIAIQSK RLATIIRDVPIEVDLDSMVFGDYDKDELLDKFRYFGFTSLLSRLVDLVDSDDTEHVEEKIEILKLKDTEKFIDEVNKKGQ VILKTVRGQGNILEKNIIYIFISVDGEKIYYVDSNEVSKLDSIFSNNEIKKYGYNLKDDYISLKPYNINLENMYFDITIA EYLIDSTSSTSYDCSAIAMKYLSKKVKSKEELLGKGVKSKNYEDLEFEDLAEYMGQIICTVKETIPMMERSLMDMSMDGL FYHVEMPLVEVLGHMEYEGIKVDKSILDELSVEFKEIIATLEKEIYELSGEPFNINSPKQLGVILFEKLELPIIKKTKTG YSTNADVLEKLRDKHPIIDKITEYRQIVKLNSTYVEGLLNIINPESNRIHSSFNQTITTTGRISSTEPNLQNIPIKMEMG RKIRKVFIADDNCKLVDADYSQVELRVLAHMSQDENMIEAFKHHEDIHTKTASQVFNVPMEDVTSELRGAAKAVNFGIIY GKSDFGLADDLNIPVPKAKEYIESYFAKYHKIKEFMDTTVEKASEDGYAVTILNRRRYIPEIKSSNFMERNRGKRFAMNA PIQGSAADIIKIAMINVHKKLEENNLKSKLILQVHDELIVEAIDDEIDIVKKIVKEEMENAVNMDVHLDVDLNVGSSWYE TK |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| polA | YP_281523.1 | DNA polymerase I | Not tested | Not named | Protein | 7e-137 | 43 |
