Gene Information

Name : silR (Ctu_3p00670)
Accession : YP_003212811.1
Strain :
Genome accession: NC_013285
Putative virulence/resistance : Virulence
Product : DNA-binding transcriptional activator CusR
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG0745
EC number : -
Position : 47953 - 48657 bp
Length : 705 bp
Strand : +
Note : response regulator in two-component regulatory system with CusS; regulates the copper efflux system

DNA sequence : 
ATTAGCAGCCAGCCGGGGAGCAAGATGAAAATATTGATCGTCGAAGACGAAATTAAAACAGGTGAATATCTCAGCAAAGG
GCTTACAGAGGCAGGGTTCGTAGTGGATCACGCTGATAATGGTCTTACCGGATATCATCTCGCCATGACAGCCGAGTATG
ATTTAGTCATTCTGGATATCATGCTACCTGATGTGAACGGCTGGGATATCATCCGCATGCTGCGCACTGCCGGAAAGGGT
ATGCCGGTCTTACTGCTGACAGCCCTCGGCACGATCGAACATAGGGTCAAAGGACTGGAACTGGGTGCGGACGATTATCT
GGTTAAACCCTTTGCGTTTGCCGAACTGCTCGCCCGGGTGAGAACCCTTCTGAGGCGGGGAAACACGATGATCACGGAAA
GCCAGTTTAAGGTGGCTGACCTCTCGATTGATCTCGTATCCAGAAAAGTCAGTCGCGCCGGAAACCGCATTGTGCTCACC
AGTAAAGAGTTCAGCCTGCTGGAATTCTTCATTCGCCATCAGGGAGAGGTTCTTCCCCGCTCCCTGATTGCCTCTCAGGT
CTGGGACATGAATTTTGACAGCGACACTAATGCGATCGATGTCGCAGTAAAGCGACTCCGCGCTAAAATAGACAACGATT
ACGAGACAAAGCTGATCCAGACAGTCCGGGGCGTGGGCTACATGCTGGAGGTCCCGGATGCATAG

Protein sequence : 
MSSQPGSKMKILIVEDEIKTGEYLSKGLTEAGFVVDHADNGLTGYHLAMTAEYDLVILDIMLPDVNGWDIIRMLRTAGKG
MPVLLLTALGTIEHRVKGLELGADDYLVKPFAFAELLARVRTLLRRGNTMITESQFKVADLSIDLVSRKVSRAGNRIVLT
SKEFSLLEFFIRHQGEVLPRSLIASQVWDMNFDSDTNAIDVAVKRLRAKIDNDYETKLIQTVRGVGYMLEVPDA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
copR NP_460069.2 transcriptional regulatory protein YedW Not tested SPI-5 Protein 9e-56 54
copR AAC33719.1 regulatory protein CopR Not tested SPI-5 Protein 3e-55 53

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
silR YP_003212811.1 DNA-binding transcriptional activator CusR BAC0347 Protein 4e-95 93
silR YP_003212811.1 DNA-binding transcriptional activator CusR BAC0111 Protein 7e-96 88
silR YP_003212811.1 DNA-binding transcriptional activator CusR BAC0083 Protein 4e-71 62
silR YP_003212811.1 DNA-binding transcriptional activator CusR BAC0638 Protein 4e-65 62
silR YP_003212811.1 DNA-binding transcriptional activator CusR BAC0197 Protein 1e-65 60
silR YP_003212811.1 DNA-binding transcriptional activator CusR BAC0308 Protein 2e-62 58
silR YP_003212811.1 DNA-binding transcriptional activator CusR BAC0125 Protein 6e-64 56
silR YP_003212811.1 DNA-binding transcriptional activator CusR HE999704.1.gene1202. Protein 3e-36 41
silR YP_003212811.1 DNA-binding transcriptional activator CusR AE000516.2.gene3505. Protein 1e-27 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
silR YP_003212811.1 DNA-binding transcriptional activator CusR VFG0596 Protein 4e-56 54
silR YP_003212811.1 DNA-binding transcriptional activator CusR VFG1390 Protein 1e-42 43