Gene Information

Name : topB (CTU_18110)
Accession : YP_003210174.1
Strain : Cronobacter turicensis z3032
Genome accession: NC_013282
Putative virulence/resistance : Unknown
Product : DNA topoisomerase III
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0550
EC number : 5.99.1.2
Position : 1890231 - 1892177 bp
Length : 1947 bp
Strand : +
Note : -

DNA sequence :
ATGCGGTTGTTTATTGCCGAAAAGCCCAGCCTGGGGCGCGCCATCGCCGACGTGTTGCCTAAGCCGCACCGCCGGGGCGA
CGGGTTTATTGAGTGCGGGAACGGCCAGGTGGTCACCTGGTGCGTCGGGCATCTGCTGGAGCAGGCGCAGCCGGACGCTT
ACGACAGCCGCTATGGCCGCTGGAATCTCGCCGACTTACCCATCGTGCCGGAAAAGTGGCAGCTTCAGCCGAAACCGTCG
GTCGCAAAGCAGCTCAATGTGATTAAAAAGCTGCTGCGCGAGGCGCAGGAGATAGTGCATGCGGGCGACCCGGATCGCGA
AGGGCAACTGCTGGTGGACGAAGTGCTCGACTACCTGCAACTGCCCGCGGAAAAGCGCCAGCAGGTGCGCCGCTGCCTGA
TTAACGATCTCAACCCGCAGGCGGTGGAGCGCGCTATCGACAAGCTGCGCGAGAACCGCGAGTTTGTCCCGCTCAGCACC
TCGGCGCTCGCCCGCGCCCGCGCCGACTGGCTTTACGGCATTAACATGACGCGCGCCTATACGCTGCTCGGGCAGAACGC
GGGCTATCAGGGCGTGCTCTCGGTAGGCCGCGTCCAGACGCCCGTGCTGGGGCTGGTGGTGCGGCGCGACGAAGAGATAG
AACACTTCGTCGCCAAAGATTTCTTTGAAGTCAAAGCGCACATCGTTACGCCCGCCCAGGAGCGCTTCACCGCGCTCTGG
CAGCCGAGCGAGGCCTGCGAGCCGTATCAGGATGAAGAGGGGCGGCTTCTGAACCGGGCCCTGGCGGAGCATGTCGTTAA
GCGTATCGAAGGGCAGCCTGCGCGTGTCACCAGCTACAACGACAAACGCGAAGGCGAAGCCGCGCCGCTGCCGTTCTCGC
TCTCGACGCTGCAAATCGAGGCCTCAAAACGCTTTAACCTGAGCGCGCAGGCAGTGCTGGATATCTGCCAGAAGCTGTAC
GAAACCCACAAACTCATTACGTATCCGCGCTCCGACTGCCGCTACCTGCCGGAGGAGCACTTCGCGGGCCGCCATGCGGT
GCTGAAGGCGATAGGCGTCCATGCGTCGGATCTGCTGCCGCAGCCCGCAGTCGATCCTGAGCGTCGCAACCGCTGCTGGG
ACGACAAAAAAGTGGACGCCCACCACGCCATCATCCCGACGGCGCGCAGCGCGCCCGCGTCGCTCTCTGACGGCGAAGCG
AAAATCTACGGGCTTATCGCCCGTCAGTACCTGATGCAGTTCTGTCAGGACGCGCAGTTTCGCAAATGCGTCATTGAGCT
TGACATCGCGGGCGGCAAATTCATCGCTAAAGCGCGCTTTCTGGCTGAGGCGGGCTGGCGCACGCTGCTCGGCGCGAAAG
AGCGCGACGAAGAGAACGACGGCACGCCGCTGCCGGTGGTCGCAAAGGGCGACGAGCTGCATTGCGAACGGGGTGAAGTG
GTCGAACGTCAGACCCAACCGCCGCGCCATTTCACCGACGCCACGCTCCTGTCGGCCATGACCGGTATCGCGCGCTTCGT
GCAGGATAAAGATCTGAAAAAAATCCTGCGCGCCACCGACGGGCTCGGCACGGAAGCGACCCGCGCAGGGATTATCGAGC
TGCTGTTTAAGCGCGGTTTTCTTGAAAAGCAGGGGCGCTATATCCACTCGACGCCCGCCGGAAAAGCGCTGATCCACGCG
CTGCCGGAGCTTGCCGCGCGCCCGGACATGACCGCGCAGTGGGAGTCGACGCTGACGCAAATCAGTGAGAAGCAGTGCCG
CTATCAGGATTTCATGCAGCCGCTGGTGCACACGCTCTACACGCTGATTGACCAGGCGCGTAGCGCCCCGGTGCGTCAGT
TCCGCGGTCTGGTGGCGCCCCAGCAGGCGCAAAAACGCCGCGCGGGCAAGGGCGGCAAAAAGCCTGCCGCCCGCAAACGC
AGCGGCGCGCAACCGGCGACGGAGTAA

Protein sequence :
MRLFIAEKPSLGRAIADVLPKPHRRGDGFIECGNGQVVTWCVGHLLEQAQPDAYDSRYGRWNLADLPIVPEKWQLQPKPS
VAKQLNVIKKLLREAQEIVHAGDPDREGQLLVDEVLDYLQLPAEKRQQVRRCLINDLNPQAVERAIDKLRENREFVPLST
SALARARADWLYGINMTRAYTLLGQNAGYQGVLSVGRVQTPVLGLVVRRDEEIEHFVAKDFFEVKAHIVTPAQERFTALW
QPSEACEPYQDEEGRLLNRALAEHVVKRIEGQPARVTSYNDKREGEAAPLPFSLSTLQIEASKRFNLSAQAVLDICQKLY
ETHKLITYPRSDCRYLPEEHFAGRHAVLKAIGVHASDLLPQPAVDPERRNRCWDDKKVDAHHAIIPTARSAPASLSDGEA
KIYGLIARQYLMQFCQDAQFRKCVIELDIAGGKFIAKARFLAEAGWRTLLGAKERDEENDGTPLPVVAKGDELHCERGEV
VERQTQPPRHFTDATLLSAMTGIARFVQDKDLKKILRATDGLGTEATRAGIIELLFKRGFLEKQGRYIHSTPAGKALIHA
LPELAARPDMTAQWESTLTQISEKQCRYQDFMQPLVHTLYTLIDQARSAPVRQFRGLVAPQQAQKRRAGKGGKKPAARKR
SGAQPATE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pph56 CAI36097.1 Topoisomerase IA Not tested PPHGI-1 Protein 2e-101 41
topB AAN62317.1 putative DNA topoisomerase III Not tested PAGI-3(SG) Protein 9e-103 41
topB AAN62194.1 putative DNA topoisomerase III Not tested PAGI-2(C) Protein 3e-103 41
topB1 YP_005176228.1 DNA topoisomerase III Not tested ICEPmu1 Protein 1e-111 41