Gene Information

Name : aldB (DAMO_1526)
Accession : YP_003206417.1
Strain : Candidatus Methylomirabilis oxyfera
Genome accession: NC_013260
Putative virulence/resistance : Virulence
Product : aldehyde dehydrogenase
Function : -
COG functional category : -
COG ID : -
EC number : 1.2.1.-
Position : 1289657 - 1291177 bp
Length : 1521 bp
Strand : -
Note : Evidence 2b : Function of strongly homologous gene; Product type e : enzyme

DNA sequence :
ATGCGTTATATCGCCCCAAACCAACCGGATAGCAAAATCCACTTCAAACCACGTTATGGTAATTTTATCGGCGGCAACTG
GGTCGCTCCCGTTACAGGCCAGTACTTTGATAACCTAAGCCCTGTAACCGGGGAGAAATTCTGTGAAATACCTCGTTCTT
CGGCGGAAGACATAGATATGGCATTGGATGCGGCGCATGCCGCTAAAGACGCGTGGGGTAAAACTTCAGTCACCGCTAGA
TCAAATATCCTGTTAAAAATTGCTGACCATATCGAAGCGAATCTTGAAACATTAGCGATTGCCGAAACGTGGGACAACGG
TAAGCCCATCCGTGAAACATTGGCGGCGGACGTACCGTTGGCAGTAGACCACTTTCGCTATTTCGCCGGCTGTATTCGTG
CCCAGGAAGGCTCCATTGGCGAAATTGACGAACACACGGTGGCGTATCATTTTCACGAGCCGCTCGGTGTCGTTGGGCAG
ATCATTCCCTGGAATTTTCCGTTATTGATGGCGTGCTGGAAACTCGCCCCTGCCCTGGCGGCGGGTAACTGTGTGGTGAT
GAAGCCCGCCGAACAAACCCCTGCATCAATTTTGGTCATGATGGAATTAATCGGCGACTTATTACCGCCGGGCGTTGTCA
ATATCGTGAACGGCTATGGCGCGGAAGCGGGGCAGGCATTGGCCACCAGCAAGCGGATTGCAAAAATAGCGTTCACCGGT
TCCACGCCTGTAGGCTCGCATATCCTGAAATGCGCGGCGGAAAACATTATTCCTTCCACGGTTGAACTGGGCGGTAAATC
GCCCAATCTCTATTTCGAGGATGTCTTAGATCAAGAAGATGCGTTTGTCAGCAAATGCGTGGAAGGTGCGGTATTGGCCT
TTTTCAATCAAGGCGAAGTGTGTACCTGCCCCTCACGCTTGCTCATTCAAGAATCGATCTATGATGCGTTTATCGCCAAG
GTGATAGCGCGTGCCAAACAAATAACACGCGGCAATCCTTTGGATACCGAAACGATGGTCGGCGCACAAGCCTCCAAACA
GCAATTCGATAAAATTTTACGTTATATCGAAATCGGCAGAAATGAAGGCGCCGAAGTGTTAGTAGGTGGTGACATTGCTG
CCATAGGCGGTGGTTTGTCTGGCGGCTATTATATTGAGCCAACGATCATGAAAGGCAGCAATGACATGCGGATTTTTCAG
GAGGAGATTTTTGGGCCGGTTATTGCCGTCACTACTTTCAAAGATGAGGCAGACGCCTTGGCTATCGCCAATGACACCGA
ATTTGGTTTAGGGGCCGGGGTTTGGACACGCGACATGAACCGCGCCTATCGTATGGGGCGTGGTATCCAGGCCGGACGTG
TCTGGACAAACTGCTACCATCATTATCCCGCCCACGCTGCGTTTGGCGGCTACAAAAAATCAGGTGTCGGTCGTGAAACC
CATAAAATGATGCTGGATCATTATCAGCAAACCAAAAATCTGCTGGTCAGTTACGATATTAATCCATTGGGATTTTTCTA
G

Protein sequence :
MRYIAPNQPDSKIHFKPRYGNFIGGNWVAPVTGQYFDNLSPVTGEKFCEIPRSSAEDIDMALDAAHAAKDAWGKTSVTAR
SNILLKIADHIEANLETLAIAETWDNGKPIRETLAADVPLAVDHFRYFAGCIRAQEGSIGEIDEHTVAYHFHEPLGVVGQ
IIPWNFPLLMACWKLAPALAAGNCVVMKPAEQTPASILVMMELIGDLLPPGVVNIVNGYGAEAGQALATSKRIAKIAFTG
STPVGSHILKCAAENIIPSTVELGGKSPNLYFEDVLDQEDAFVSKCVEGAVLAFFNQGEVCTCPSRLLIQESIYDAFIAK
VIARAKQITRGNPLDTETMVGAQASKQQFDKILRYIEIGRNEGAEVLVGGDIAAIGGGLSGGYYIEPTIMKGSNDMRIFQ
EEIFGPVIAVTTFKDEADALAIANDTEFGLGAGVWTRDMNRAYRMGRGIQAGRVWTNCYHHYPAHAAFGGYKKSGVGRET
HKMMLDHYQQTKNLLVSYDINPLGFF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 2e-164 69
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 8e-173 68
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 8e-173 68
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 8e-173 68
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 4e-172 68

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
aldB YP_003206417.1 aldehyde dehydrogenase VFG0082 Protein 7e-165 69