Gene Information

Name : clpB (DAMO_1073)
Accession : YP_003205972.1
Strain : Candidatus Methylomirabilis oxyfera
Genome accession: NC_013260
Putative virulence/resistance : Virulence
Product : chaperone
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 904360 - 906957 bp
Length : 2598 bp
Strand : +
Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 12054807, 12220194; Product type f : factor

DNA sequence :
ATGGCCTTTATGCGATTCGATAAATTTACCTTTAAGGCGCAGGAGGCGATTCAGCAGGCCCAGAAGCTGGCTGAGCAGCT
GGAGCATCAGGCAATTGATGTTGAGCACCTGTTGTTAGCGCTTGTACAACAGGCGGAAGGGGTCGTCCAGCCGATTCTGG
GAAAGATGGGGACTGACCCCCGTCAGGTCGCCTCCAGACTCACAGAGGAACTGAAGCGACTTCCCAGGGTCTCCGGGCTT
CCACCAGGCCAGGTCCATATCACTCCACGTCTTGAAAAGGTGCTGAGCGCCGCGCTGTCTGAGGCGGAACGCTTGAAAGA
TGAGTACGTCAGCACCGAGCATCTGCTTCTGGCGATTGCCGACGCGGGCGGTGGCGCCGTCGGGAGGGTCCTGCGCGAGG
CTGGGATTACAAAAGACACTATTTACGCAGCTTTGCAGGAGGTTCGCGGCAGCCAGCGAGTCACCGATCAGGTTCCGGAG
GAAAAGTACCAGGCGTTGGAACGGTACGCCCGCGATCTCACCGATCTGGCCAGAAAAGGGAAGCTGGACCCGGTCATCGG
TCGAGACGATGAGATCCGTCGAGTGGTTCAGGTCCTGGCGCGCCGAACCAAAAACAACCCGGTTCTCATTGGTGAGCCCG
GCGTGGGGAAGACCGCCATCGTAGAAGGACTGGCGCAGCGAATCGTCAATGGCGACGTACCGGAGTCGTTGAAGAATAAG
CGTGTGCTGGCGCTGGATATTGGCGCACTGGTGGCCGGGAGTAAGTACCGCGGGGAGTTCGAAGACCGGCTGAAGGCGGT
CCTTCGGGAGGTGACCGAGCAGCAGGGTCAGATTGTTCTCTTCATCGATGAACTCCATACCCTTGTTGGAGCCGGCGCTG
CTGAAGGGGCCGTGGATGCCTCGAACATGCTCAAGCCGGCGCTGGCTCGAGGAGAGCTTCGGTGTGTGGGGGCTACGACA
CTGGACGAATACCACAAGCGGGTAGAGAAAGACGCAGCGCTAGAACGGCGCTTCCAACCGGTCCTGGTCGGCGAGCCGTC
GGTAGAAGATAGCATCTCGATTCTTCGCGGGCTGAAGGAACGGTACGAGGTGCACCACGGTGTAAGGATCAGGGACTCGG
CGCTGGTGGCGGCCGCCATCTTAAGCAACCGGTACATCACCGACCGGTTCTTGCCGGACAAAGCGATCGACCTGATCGAT
GAGGCGGCGTCTCGTCTGCGGATGGAGATCGACAGCATGCCGACGGAGCTGGACGAGCTCAGTCGGCGAATACGACAGAT
CGAGGTCGAATACCACGCTCTGAAGAAGGAGACCGATTCAGAGTCGCAGGAACGCCTCGCGCGTCTGGCCGACGAGCTCG
TGGAGATCCGGATCAAGGAGGAAGGTCTCAAGACCCGCTGGGAGCAGGAGAAGGGATTCATCCAGCGAATCAGGGGCCTC
AAGGAGCGGATCGAGGCGGCGAAGGTGCAGGAGCAGATGGCGGAGCGACAGGGCGATCTGGGAAAGGTCGCCGAACTCCG
CTATGGTGTGGTTACATTGCTGCAAAAGGAGTTGGAAAGCGAAAAGCGCGGGCTGGAACAGGTCCAGCAGGTTGGCGCCA
TGCTCAAGGAGGAGGTAGACGAGGAAGATGTCGCCCAAGTCGTCTCTAAGTGGACCGGGGTTCCGGTTGCCAGGATGCTG
GAAGGCGAAACCCAGAAGCTCCTGACCATGGAGGAGAAGCTCAGGGAGCGAGTGGTGGGGCAGTACGAGGCGATTGGCGC
AGTGAGTGACGCGATCCGGCGCGCCCGCTCCGGGCTTCAGGATCCGAACCGGCCGATCGGCTCCTTCATGTTCCTGGGGC
CGACGGGTGTTGGAAAGACCGAGCTGGCCCGGGCATTGGCCGCGTTCCTGTTCGACGACGAGCGGGCGATGATTCGCCTG
GACATGAGCGAGTACATGGAGAAGCATACCGTCTCTCGCCTCATCGGCGCGCCGCCTGGCTACGTCGGGTTCGAGGAGGG
GGGACAGCTCACTGAGGCGGTTCGGCGTCGCCCCTACTGCGTCCTGCTCCTGGACGAGATCGAAAAGGCCCACACCGATG
TCTTCAATATCCTGCTGCAGATTCTGGATGATGGACGGCTGACCGATGGGCAGGGGCGAACCGTGGACTTCAAAAACACG
ATCATCATCATGACCAGCAACCTGGGGAGTCAGGTCATTCAGGAGTTAGGCGGTCGCGATGATGAGGAGATGCGTCGGCG
AGTACTGGAGGCCGTAAGAACTCACTTTCGGCCGGAGTTCCTGAACCGAGTAGACGAGATACTGATTTTCCACACTCTCT
CGCTGGCTCAGATCAAAGCGATTGTGGAGATCCAGCTCAGGCGGGTGGGGAAGCGGCTTGTCGAGCGGAAGCTCGATCTT
GAGGTCACGGATGCGGCAAAGGACTTTCTGGCCAAAGAAGGATACGATCCGGTCTTTGGGGCGAGACCGCTCAGGCGAGC
CATCCAGCGAGCGCTGTTGGATCCCTTGGCGCGTCGTCTGTTGGAGCATGAGTTTGCCGAAGGCGACACCGTGAGGGTCG
ATGCGGCTCGCGGAGAACTGATCCTGAGTAAGGATTGA

Protein sequence :
MAFMRFDKFTFKAQEAIQQAQKLAEQLEHQAIDVEHLLLALVQQAEGVVQPILGKMGTDPRQVASRLTEELKRLPRVSGL
PPGQVHITPRLEKVLSAALSEAERLKDEYVSTEHLLLAIADAGGGAVGRVLREAGITKDTIYAALQEVRGSQRVTDQVPE
EKYQALERYARDLTDLARKGKLDPVIGRDDEIRRVVQVLARRTKNNPVLIGEPGVGKTAIVEGLAQRIVNGDVPESLKNK
RVLALDIGALVAGSKYRGEFEDRLKAVLREVTEQQGQIVLFIDELHTLVGAGAAEGAVDASNMLKPALARGELRCVGATT
LDEYHKRVEKDAALERRFQPVLVGEPSVEDSISILRGLKERYEVHHGVRIRDSALVAAAILSNRYITDRFLPDKAIDLID
EAASRLRMEIDSMPTELDELSRRIRQIEVEYHALKKETDSESQERLARLADELVEIRIKEEGLKTRWEQEKGFIQRIRGL
KERIEAAKVQEQMAERQGDLGKVAELRYGVVTLLQKELESEKRGLEQVQQVGAMLKEEVDEEDVAQVVSKWTGVPVARML
EGETQKLLTMEEKLRERVVGQYEAIGAVSDAIRRARSGLQDPNRPIGSFMFLGPTGVGKTELARALAAFLFDDERAMIRL
DMSEYMEKHTVSRLIGAPPGYVGFEEGGQLTEAVRRRPYCVLLLDEIEKAHTDVFNILLQILDDGRLTDGQGRTVDFKNT
IIIMTSNLGSQVIQELGGRDDEEMRRRVLEAVRTHFRPEFLNRVDEILIFHTLSLAQIKAIVEIQLRRVGKRLVERKLDL
EVTDAAKDFLAKEGYDPVFGARPLRRAIQRALLDPLARRLLEHEFAEGDTVRVDAARGELILSKD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 3e-147 50
aec27 AAQ96721.1 Aec27 Not tested AGI-1 Protein 5e-97 42
aec27 YP_851418.1 ATPase Not tested PAI II APEC-O1 Protein 7e-97 42
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 3e-103 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpB YP_003205972.1 chaperone VFG2076 Protein 1e-114 44
clpB YP_003205972.1 chaperone VFG2084 Protein 9e-100 41