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Name : leuS (Namu_5392) Accession : YP_003204644.1 Strain : Nakamurella multipartita DSM 44233 Genome accession: NC_013235 Putative virulence/resistance : Unknown Product : leucyl-tRNA synthetase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG0495 EC number : - Position : 6031008 - 6033944 bp Length : 2937 bp Strand : - Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl DNA sequence : ATGACCAGCCCGACGACCCAGACGGTGACGCCGGCCGCGGTGCCGACCGTGGCGAGCGAGGCCGCGCCACCGTTCCGCTA CACCGCCGCGCTGGCGGCCGACATCGAACAGCGGTGGCAGGACCGCTGGGAGGCCGAGGGCACCTTCCAGGCGCCCAACC CGGCCGGACCGCTGGCTCCGGCCGACGGTTCCCCGGTCCCCAAGGACAAGCTGTACCTGCTGGACATGTTCCCCTACCCC TCCGGGGCCGGCCTGCACGTCGGGCACCCGCTGGGGTACATCGGCACCGACGTGATCGGCCGGTTCATGCGGATGACCGG ACGCAACGTGCTGCACACCATCGGCTACGACGCCTTCGGCCTGCCGGCTGAGCAGTACGCGGTCCGGACCGGCACCCACC CGCGGACCACCACCGAGGCCAACATCACCCGCTACCGCGCGCAGCTGCGGCGGCTGGGCTTCGCGCACGATCAGCGGCGC AGCGTGGCCACCACCGATCCCGAGTTCTTCCGCTGGACCCAGTGGATCTTCACCCAGCTGTTCGAGGCCTGGTACGACGA GCAGGCCGGGCGGGCCCGGAGTATCGCCGACCTGATCCAGGAGTTCGCCGCCGGCACCCGGGCGACCCCGGACGGCCGGC CCTGGGCGCAGCTGTCGCACGTCGAGCAGCACCAGGTGCTGGCCGGCTACCGCTTGGCCTACATCGACGAGGCCCCGGTG AACTGGTGCCCGGGCCTGGGCACCGTGCTGTCCAATGAAGAGGTCACCGCCGACGGGCGCAGTGCGATCGGCAACTACCC GGTGTTCCGGCGCAGCCTGCGCCAGTGGATGATGCGGATCACCGCTTACGCCGACCGGCTGCTGGACGACCTGGACCGGT TGGACTGGCCGGAGTCGGTCAAGTCGATGCAGCGCAACTGGATCGGCCGCTCCTACGGGGCCACCGTCTCGTTCCCGGTT GCTTCGCGTGAAACGTCACGGGAAGGGTTGCCGGACAACGGATCCGGCTCCGATATGGCCGGCATCGAGGTCTATACGAC CCGTCCGGACACCCTGTTCGGAGCCACCTACATGGTGCTGGCGCCCGAGCATCCGCTGGTCGAGTCGATCACCGCGACCC GCTGGCCGCGGGGCACCGACCCGCGCTGGACCGGAGGGGCGGACACCCCGGCTCAGGCGATCGCCGAGTACCGGCTGGCC GCCTCGCGCAAGTCCGACCTGGACCGGCAGGAGAACAAGGACAAGACCGGCGTCTTCACCGGGGCCTACGCGACCAACCC GGCCACCGGGACCGATCTGCCCATCTTCATCGCCGACTACGTGCTGATGGGGTACGGCACCGGCGCGATCATGGCGGTGC CGGCCGAGGACACCCGGGACTTCGACTTCGCCACCGCCTTCGGCCTGCCGATCGTGCGCACCGTGCAGCCGCCGGCCGAT CACCCGGAGGATCAGGCCTACACCGGCGACGGCCCGACCATCAACAGCGCGAACGACGAGATCAGCCTGAACGGGCTGGA TGTGGTGGCGGCCAAGGCGGCCATCATCGACTGGCTGACCGCCAAGGGGGTCGGCCAGGCCCGCAAGCAGTACAAGCTGC GGGACTGGCTGTTCTCCCGGCAGCGGTACTGGGGCGAGCCGTTCCCGATCGTCTACGACGAGCACGGCGTGGCCATCTCC CTGCCCGACGAGCTGCTGCCGCTGACCCTGCCGGAGGTCTCGGACTACTCGCCGCAGTCGTTCGATCCCCAGGACGCCAC GTCCCAGCCGGTTCCGCCGCTGGCCCGGGCGACCGAGTGGGCCACCGTCGAGCTGGATCTGGGTGACGGGCCCAAGACCT ACACCCGCGAGCTGAACGTGATGCCGCAGTGGGCCGGGTCCTGCTGGTACGAGCTGCGCTACCTGGATCCCACCAACGAC AAGACCTTCTGCGATCCCGAGGTCGAGCGGTACTGGATGGGCAAGAATCCCGACCGGCCGAACGACCCGGGCGGGGTCGA CCTGTACGTCGGCGGCGTCGAGCACGCGGTGCTGCACCTGCTGTACTCCCGGTTCTGGCACAAGGTGCTGTTCGACCTGG GCCACGTCTCCAGCGAGGAGCCGTACCGCAAGCTGTTCAACCAGGGCTACATCCAGGCGTACGCGTACACCGACGAGCGC GGCCTGTACGTGCCGGCCGACGAGGTCACCGAGGTGGCGCCGGAGAAGTTCGAGTACCAGGGGCGGCCGGTCACCCGTGA GTACGGGAAGATGGGCAAATCCCTGAACAATGTCGTCACGCCGGACGAGATGTGCGAACGCTTCGGCGCCGACACGTTCC GGATGTACGAGATGGGCATGGGTCCGATGGACATGTCCCGGCCCTGGCAGACCCGGGACGTCGTCGGTTCCCAGCGCTAC CTGCAGCGGCTGTGGCGGTTGGTGGTCGACGAATCCACTGGGGACACCGTCGTCGCCGACGCCGAACCGGATCTGCAGAC CCAGCGGCTGCTGCATCGCACCATCGACGGGGTGCGCGCCGACTACGCGGCGATGGGCTACAACACGGCGATCGCCAAGC TGATCGTGCTGACCAACCACCTGACCAAGTCCGGGGCGCCGGTGCCGCGGACGGTGGCCGAGGCGCTGGTGCTGATGACG GCGCCGCTGGCCCCGCACATCGCCGAGGAGATGTGGGCGCGGCTGGGTCACTCCCGGTCGCTGGCTCACGGGCCGTTCCC GGAGGCCGACCCGGCCCTGCTGGTGGCCGAGCAGGTCGAGTACCCGATCCAGGTCAAGGGCAAGGTCCGGGGTCGGATCA CCATCGACGCCACGGCCGCCGTGTCCGCGATCGAGGCGGCCGCGCTGGCCGAGCCGCGGATCGTCGAACTGCTGGCCGGG GCGACGCCCCGCAAGGTGGTCGTCGTCCCCGGCAAGATGGTCTCGATCGTGCCGTAG Protein sequence : MTSPTTQTVTPAAVPTVASEAAPPFRYTAALAADIEQRWQDRWEAEGTFQAPNPAGPLAPADGSPVPKDKLYLLDMFPYP SGAGLHVGHPLGYIGTDVIGRFMRMTGRNVLHTIGYDAFGLPAEQYAVRTGTHPRTTTEANITRYRAQLRRLGFAHDQRR SVATTDPEFFRWTQWIFTQLFEAWYDEQAGRARSIADLIQEFAAGTRATPDGRPWAQLSHVEQHQVLAGYRLAYIDEAPV NWCPGLGTVLSNEEVTADGRSAIGNYPVFRRSLRQWMMRITAYADRLLDDLDRLDWPESVKSMQRNWIGRSYGATVSFPV ASRETSREGLPDNGSGSDMAGIEVYTTRPDTLFGATYMVLAPEHPLVESITATRWPRGTDPRWTGGADTPAQAIAEYRLA ASRKSDLDRQENKDKTGVFTGAYATNPATGTDLPIFIADYVLMGYGTGAIMAVPAEDTRDFDFATAFGLPIVRTVQPPAD HPEDQAYTGDGPTINSANDEISLNGLDVVAAKAAIIDWLTAKGVGQARKQYKLRDWLFSRQRYWGEPFPIVYDEHGVAIS LPDELLPLTLPEVSDYSPQSFDPQDATSQPVPPLARATEWATVELDLGDGPKTYTRELNVMPQWAGSCWYELRYLDPTND KTFCDPEVERYWMGKNPDRPNDPGGVDLYVGGVEHAVLHLLYSRFWHKVLFDLGHVSSEEPYRKLFNQGYIQAYAYTDER GLYVPADEVTEVAPEKFEYQGRPVTREYGKMGKSLNNVVTPDEMCERFGADTFRMYEMGMGPMDMSRPWQTRDVVGSQRY LQRLWRLVVDESTGDTVVADAEPDLQTQRLLHRTIDGVRADYAAMGYNTAIAKLIVLTNHLTKSGAPVPRTVAEALVLMT APLAPHIAEEMWARLGHSRSLAHGPFPEADPALLVAEQVEYPIQVKGKVRGRITIDATAAVSAIEAAALAEPRIVELLAG ATPRKVVVVPGKMVSIVP |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| leuS | YP_281511.2 | leucyl-tRNA synthetase | Not tested | Not named | Protein | 5e-131 | 45 |
