Gene Information

Name : Namu_4066 (Namu_4066)
Accession : YP_003203345.1
Strain : Nakamurella multipartita DSM 44233
Genome accession: NC_013235
Putative virulence/resistance : Resistance
Product : ABC transporter
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG1136
EC number : -
Position : 4481046 - 4481927 bp
Length : 882 bp
Strand : -
Note : PFAM: ABC transporter; SMART: ATPase AAA; KEGG: mxa:MXAN_4199 macrolide efflux ABC transporter ATP-binding protein

DNA sequence :
ATGGATGCGGGCGCGACTGCCGACCGATGCCCGCGACGCCGCGTGATCCCTAGCGTCGCAGGCATGTTGATCGGACAGAG
CGCCCCCCGCCCCGCGGCCCGGGTGCAGCAGTTGACCAAGACCTACGGCTCCGGCGAAGGGATGGTGCACGCGCTGGCCG
GGGTCAGCGTGAGCATCCGCCGCGGCGAGTTCACCGCGATCATGGGCCCGTCCGGGTCCGGCAAGTCCACCCTGATGCAC
ATCATGGCCGGGCTGGACGCGCCGTCCTCCGGTCAGGCGTGGATCGGCGACACCAAGATCACCGGCCGCTCGGACACCGA
GCTGACCGTGCTGCGCCGGCGCCGCATCGGGTTCGTGTTCCAGGCCTTCAACCTGGTGCCCACGCTGGACGCGCTGGGCA
ACATCCTGCTGCCGTTCGACCTGGACGGTCGCCGCCCCACCGACGCCGAACGGACTCGGGTCGATCGGCTGATCTCCGCG
CTGGGCCTGTCCGGCCGGCTGCGCCACCGGCCGCACCAGCTCTCCGGCGGGCAGCAGCAGCGGGTGGCCATCGCCCGCGC
CCTGGCCACCGCGCCCGACCTGGTCTTCGCCGACGAGCCGACCGGCAACCTGGACTCGCGCAGCAGCCGTCAGGTGCTCG
GTCTGCTGGCCGTGGCCAGCCGGGAGGGTGGGCAGTCCATCGCCATGGTCACCCACGACCCGATCGCGGCCGCGTACGCG
GACCGGGTGCTGTTCCTCGGCGACGGCCGCATCGTGGCCGACAAGCCCCGGCAGACCGCCGAGCAGATCGCCGCGTTCCT
GCTGGCCGCGGAGCCGGCGCCCGAGACCGGGAGCGCGACCGGCGCGACGACGACGGCCGCGACCCAGCAGGTGCCGGCAT
GA

Protein sequence :
MDAGATADRCPRRRVIPSVAGMLIGQSAPRPAARVQQLTKTYGSGEGMVHALAGVSVSIRRGEFTAIMGPSGSGKSTLMH
IMAGLDAPSSGQAWIGDTKITGRSDTELTVLRRRRIGFVFQAFNLVPTLDALGNILLPFDLDGRRPTDAERTRVDRLISA
LGLSGRLRHRPHQLSGGQQQRVAIARALATAPDLVFADEPTGNLDSRSSRQVLGLLAVASREGGQSIAMVTHDPIAAAYA
DRVLFLGDGRIVADKPRQTAEQIAAFLLAAEPAPETGSATGATTTAATQQVPA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
Cp1002_1464 YP_005681730.1 ABC transporter ATP-binding protein Not tested PiCp 5 Protein 6e-34 46
CpI19_1473 YP_005685914.1 ABC transporter ATP-binding protein Not tested PiCp 5 Protein 1e-34 45
CpC231_1466 YP_005683828.1 ABC transporter ATP-binding protein Not tested PiCp 5 Protein 1e-34 45
cpfrc_01473 YP_003783873.1 hypothetical protein Not tested PiCp 5 Protein 1e-34 45

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Namu_4066 YP_003203345.1 ABC transporter CP001581.1.gene798.p Protein 5e-46 50
Namu_4066 YP_003203345.1 ABC transporter CP001581.1.gene598.p Protein 3e-51 47
Namu_4066 YP_003203345.1 ABC transporter NC_008702.1.4606598. Protein 3e-36 46
Namu_4066 YP_003203345.1 ABC transporter NC_012469.1.7685735. Protein 1e-33 41