Gene Information

Name : Namu_0231 (Namu_0231)
Accession : YP_003199651.1
Strain : Nakamurella multipartita DSM 44233
Genome accession: NC_013235
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 259984 - 261246 bp
Length : 1263 bp
Strand : +
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
GTGATCGACCTGCGCATCGTTCGTGACGACCCCGACCGTGTCCGCGCCTCCCAGCACGCTCGTGGGGAGGATTCCGGGGC
GGTCGATCGGCTGCTGGCGGCCGACGCGGACCGCCGGGCCGCGGTCGCCCGGGCCGACTCGCTGCGCGCCGAGCAGAAGT
CCTACGGCCGGACGATCGGCCAGGCGAGCAAGGACGAGCGGCCGGCCCTGCTGGAGCGGGGCAAGGCGATGGCGGCCGAG
GTCAAGCTGGCCGAGGCGGCCGAGCAGGAGGCCAACGCCGCCCTGGCGGTGGCCCACCGGTCCATCGCCAACATCATCGA
GGGGGCCCCGCCCGGCGGCGAACAGGACTACCTGGTGGTCAAGGAGGTCGGCAGGCCGACCGAGTTCGACTTCACCCCGC
GGGACCACGTCGAGCTGGGCGAACGTCTCGGCGCGATCGACATCGAGCGGGGCACCAAGGTGTCCGGGGCCCGCTTCTAC
TTCCTGCGGGGGGTCGGCGCGCAGCTGCAGTGGGCGCTGCTGAACCTGGCGGTGAGCACCGCGATCGGGCACGACTTCGT
GCCGATGATCCCGCCGGTGCTGGTCAAACCGGAGGCGATGGAAGGCACCGGCTTCCTCGGGGCGCACGCCGACGAGATCT
ACCGGCTCGAGGCCGACGACATGTACCTGGTCGGCACCGCCGAGGTGCCCCTGGCCGGCTACCACGCCGGCGAGATCCTC
GACCTGTCCGCCGGTCCGCTGCGCTACGCCGGCTGGTCGTCGTGCTTCCGGCGGGAGGCCGGTTCCTACGGCAAGGACAC
CCGCGGCATCCTGCGCGTGCACCAGTTCGACAAGGTCGAGATGTTCGTGTTCTGCAAGCCGGAGGACGCGGCCGATCAGC
ACGCCCAGCTGCTCTCGTTCGAGGAGCAGATGCTGGCCCAGATGGAACTGCCGTACCGGGTGATCGACACGGCGGCCGGT
GATCTGGGCTCGTCCGCGGCGCGCAAGTTCGACTGCGAGGCCTGGGTGCCGACCCAGCAGACCTACCGTGAGCTGACCTC
GACCTCGAACTGCACGACGTTCCAGGCCCGGCGGCTCGGGGTGCGGTACCGGGACGAGGACGGCAAGCCGCAGGTCGCGG
CCACCCTCAACGGCACCTTGGCCACGACCCGGTGGTTGGTCGCGATCCTGGAGAACCACCAGCAGGCGGACGGTTCGGTG
CGGGTGCCCAAGGCCCTGCAGCCCGGGCTCGGCGGCCGCGAAGTGCTGGAGCCGATCGGGTAG

Protein sequence :
MIDLRIVRDDPDRVRASQHARGEDSGAVDRLLAADADRRAAVARADSLRAEQKSYGRTIGQASKDERPALLERGKAMAAE
VKLAEAAEQEANAALAVAHRSIANIIEGAPPGGEQDYLVVKEVGRPTEFDFTPRDHVELGERLGAIDIERGTKVSGARFY
FLRGVGAQLQWALLNLAVSTAIGHDFVPMIPPVLVKPEAMEGTGFLGAHADEIYRLEADDMYLVGTAEVPLAGYHAGEIL
DLSAGPLRYAGWSSCFRREAGSYGKDTRGILRVHQFDKVEMFVFCKPEDAADQHAQLLSFEEQMLAQMELPYRVIDTAAG
DLGSSAARKFDCEAWVPTQQTYRELTSTSNCTTFQARRLGVRYRDEDGKPQVAATLNGTLATTRWLVAILENHQQADGSV
RVPKALQPGLGGREVLEPIG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 3e-59 46