Gene Information

Name : Namu_1766 (Namu_1766)
Accession : YP_003201145.1
Strain : Nakamurella multipartita DSM 44233
Genome accession: NC_013235
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 1933558 - 1934976 bp
Length : 1419 bp
Strand : -
Note : KEGG: gme:Gmet_0122 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: pyruvate kinase barrel; pyruvate kinase alpha/beta

DNA sequence : 
ATGACACGCCGCGCGAAGATCGTCTGCACCTTGGGTCCGGCCACCTCGTCGGAGGAGGCGATCGCCGCTCTGCTGGACGC
CGGGATGAACGTGGCCCGGATGAATTTCTCGCACGGTGATTACGCGGACCACGAAGTGATCTACCACCGGCTGCGGGATG
CGGCCAGGTCTTCCGGCAAGGCGTTGGCCATCATGGCCGACCTGCAGGGCCCCAAGATCCGCCTCGGCCGGTTCGCCGAC
GGCCCGCACGACTGGAACACCGGCGACACGGTGACCATCACGGTGCAGGATGTCGTCGGCTCCAAGGACCGGGTGTCCAC
CACCTACAAGGGCCTGGCCCGGGACGCCCGCCCGGGTGACCGTCTGCTGATCGACGACGGCAAGGTCGGCCTGGTCGTCA
CCGCCGTCGACGGCGACGACGTGACCTGCTCGGTCACCGAGGGCGGCCCCGTCTCCAACAAAAAGGGCATCTCGCTGCCC
GGCATGAACGTCTCGGTGCCGGCCATGTCCGAGAAGGACATCGCCGACCTGAAGTTCGCGCTGTCCCTGGGTGTCGACGT
GATCGCGCTGTCCTTCGTCCGCTCGCCGACCGACGTCGACCTGGTCCGCAACGTGATGGACGAGGTCGGGGCCGATCGCC
GCCCGGTCATCGCCAAGCTGGAAAAGCCCGAGGCCGTCGCCAATCTCGAAGCGATCGTGCGCGCGTTCGACGGAATCATG
GTCGCCCGCGGCGATCTGGGCGTCGAGCTGCCGCTGCAGCAGGTGCCGCTGGTCCAGAAGCGCGCCGTGCAGGTGGCCCG
GGAGAACGCCCGCCCGGTCATCGTCGCCACCCAGATGCTCGACTCGATGATCGAGCACTCTCGCCCGACCCGGGCCGAGG
CCTCGGACGTCGCCAACGCCATCCTGGACGGGGCCGACGCGGTCATGCTGTCCGGGGAGACCTCCGTCGGCAAGTACCCG
ATCATCGCCGTCAAGACCATGGCCCGGATCATCGAGGCCGTCGAGACCGAGTCGGTCGCCGCCCCCGCGCTGACCCACAC
CCCGCGAACCCGTGGTGGCGTGCTGTCTTTCGCGGCCCGCGACATCGCCGAGCGGATCGACGCCAAGGCTGTCATCGCGT
TCACCTTCACCGGTGACACCGTGCGCCGGATGGCCCGCCTGCACACCGGGCTGCCGGTCATCGCGTTCACCCCGAAGGAA
GAGGTGCGCAACCAGCTCGCGTTGACCTGGGGCGTGCGGACCTTCGTCACCCCGCCGGTGGACACCACCGACGAGATGGT
CGAGCAGGTCGACCAGGCCATGTTGGAGATCCCCGGGTTCGAGCCCGGCGACACCGTGGTCATCGTGGCCGGCGCGCCGC
CGAACACCTCCGGTTCCACCAAGCTCATTCGGGTGCACCGGCTGGGGCATCACGACTGA

Protein sequence : 
MTRRAKIVCTLGPATSSEEAIAALLDAGMNVARMNFSHGDYADHEVIYHRLRDAARSSGKALAIMADLQGPKIRLGRFAD
GPHDWNTGDTVTITVQDVVGSKDRVSTTYKGLARDARPGDRLLIDDGKVGLVVTAVDGDDVTCSVTEGGPVSNKKGISLP
GMNVSVPAMSEKDIADLKFALSLGVDVIALSFVRSPTDVDLVRNVMDEVGADRRPVIAKLEKPEAVANLEAIVRAFDGIM
VARGDLGVELPLQQVPLVQKRAVQVARENARPVIVATQMLDSMIEHSRPTRAEASDVANAILDGADAVMLSGETSVGKYP
IIAVKTMARIIEAVETESVAAPALTHTPRTRGGVLSFAARDIAERIDAKAVIAFTFTGDTVRRMARLHTGLPVIAFTPKE
EVRNQLALTWGVRTFVTPPVDTTDEMVEQVDQAMLEIPGFEPGDTVVIVAGAPPNTSGSTKLIRVHRLGHHD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 2e-77 41
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 2e-77 41
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 7e-78 41
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 7e-78 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Namu_1766 YP_003201145.1 pyruvate kinase VFG0479 Protein 3e-78 41