Gene Information

Name : Dret_1072 (Dret_1072)
Accession : YP_003197938.1
Strain : Desulfohalobium retbaense DSM 5692
Genome accession: NC_013223
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1212
EC number : 2.7.7.38
Position : 1263283 - 1264017 bp
Length : 735 bp
Strand : -
Note : CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS

DNA sequence :
ATGCCGCCTCGTTGTATCGGAATCATCCCGGCCCGATACGCTTCCTCCCGCTTTCCGGGCAAACCCCTGGCCCCTGTCCT
GGGGCGCCCCATGTTCTGGCATGTCTATACCCGGGCCTGCCGTTGCCCTGAATTGTCCCAGGTCGTCCTGGCCACGGATG
ACGAGCGTATCGTGCACAGCGCTCAGAACGAAGGAGTTCCCGTGGTCATGACCCGTTCCGACCACCCCAGCGGGTCTGAT
CGAGTCCTGGAGGCGGCCGAACATTTGGGGCTTGACGAAGAAGACATCCTGGTGAACATCCAGGGTGATGAACCGGCCTT
GGACCCGTCCATGCTTTCCGATGTGGTCCGCCCTTTCACTCAATCGGCGGTCCGTGTCGGAACCCTGGTCCGAGCTATAG
CGGAAACAGAGGCCCGGGATCCCAACGTGGTCAAAGCCGTGACCGCCCCGGACGGGCGAGCGTTATACTTTTCCCGGGCA
CCGATTCCCTATCCCCGGGACAACGTGCCAGCGTATCTCGGTCATGTCGGCCTGTACGCCTACCGTCTGCTCAGCCTGAA
ACATTTCAGCTCCCTGGGGCCCAGCGCCCTGGAACAAAAAGAACACCTGGAACAACTCCGTTTTCTGGAAGCCGGCATTC
CGATCCATACGGTACAGACAGCCTGCCGCTGCCACGGCGTGGATTGCCCGGACGACATCAAGCGGGTGGAACGTATCTTG
AAGGAGAGTCAATAA

Protein sequence :
MPPRCIGIIPARYASSRFPGKPLAPVLGRPMFWHVYTRACRCPELSQVVLATDDERIVHSAQNEGVPVVMTRSDHPSGSD
RVLEAAEHLGLDEEDILVNIQGDEPALDPSMLSDVVRPFTQSAVRVGTLVRAIAETEARDPNVVKAVTAPDGRALYFSRA
PIPYPRDNVPAYLGHVGLYAYRLLSLKHFSSLGPSALEQKEHLEQLRFLEAGIPIHTVQTACRCHGVDCPDDIKRVERIL
KESQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 8e-41 44
kpsU CAE85213.1 KpsU protein Virulence PAI V 536 Protein 1e-40 44
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 6e-41 44