Gene Information

Name : guaA (RB2501_12502)
Accession : YP_003195495.1
Strain : Robiginitalea biformata HTCC2501
Genome accession: NC_013222
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 1991367 - 1992896 bp
Length : 1530 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGCAAAATAACGTTCTCATCCTGGATTTCGGTTCCCAGTACACCCAGCTGATCGCAAGGCGGGTCCGCGAACTGAATAT
ATTCTGCGAAATCAAACCCTACAACAACCTGCCCGGCGACCTCGACGGCTACAAAGCGGTGATCCTTTCCGGCTCCCCCT
TTTCCACCCGGTCGGACGACGCCCCCCACCCGGACCTGAGCCGGATCAAAGGCCATAAACCCATCCTGGCCATCTGCTAT
GGCGCCCAGTACATTGCCCATTTTAACGGGGGAAATGTGGCCCCGTCGAAAACGCGGGAGTACGGCCGGGCTAAACTTGC
CCACGTGGCCCAGGACCCTTTCCTGAAGGATGTCCCGGTGGGTAGCCAGGTATGGATGAGCCACAGCGATACGATTCAGC
AACTGCCGGACGGGGCGGTGCTTCTGGCCAGTACCCACGACGTGCCGAATGCCGCATTCAAGATGCCGGACGAACGGATC
TACGGGATCCAGTTCCACCCTGAAGTCTACCACACCACGGCCGGAAGCCTGATCCTGAGGAATTTCCTGGTGGATATCGC
CGGCCTGGAACAAACCTGGACGCCCGCAGCCTTTGTGGAGACCACCGTGGCGGAACTCAAGGAGAAGATCGGGACCGAAA
AAGTTATTCTCGGCCTTTCCGGGGGTGTCGATTCCACGGTGGCGGCCATGTTGCTCCACCGCGCCATTGGGAAACACCTG
CACTGCATCTTTGTGAACAACGGGCTGCTGCGCAAGAATGAATTTGAAGAAGTGCTTCACCAGTATAAGGATATGGGGTT
GAACATTAAGGGCGTTGACGCTTCGGCACGCTTTTTGGATGCCCTGGAAGGGGAATCGGACCCCGAGAAGAAACGAAAGA
TCATCGGCCGGGTGTTTATCGAGGTGTTTGACGACGAAGCCCACCTGGTGGAAGATGCAAAATGGTTGGGGCAGGGAACT
ATCTATCCGGATGTTATCGAGTCGGTATCGGCTACCGGGGGGCCCTCTGCAACCATCAAGAGTCACCACAATGTGGGTGG
CCTGCCGGACTTTATGAAGCTGAAGGTGGTAGAACCACTGAAGATGCTTTTTAAGGATGAGGTGCGACGCGTGGGCGCCA
GCCTGGATATCCCGGCTGAGCGTTTGGGGAGGCACCCCTTCCCGGGTCCGGGACTGGCAATCCGCATCCTTGGGGACATT
ACCCGGGAAAAGGTCGCCATCCTCCAGGAAGTGGACCATATATTTATCAACGGACTCCGCGAATGGGGCCTGTACGACAA
GATCTGGCAGGCGGGGGCCATGCTCCTCCCGGTCAACAGCGTGGGGGTGATGGGGGACGAAAGGACTTATGAAAAATGCG
TAGCTTTACGGGCAGTGGAAAGTACGGATGGAATGACGGCCGACTGGGTCAACCTGCCGTACGAATTTCTGCAGAAGACC
TCAAATGACATTATCAATAAGGTGCCCGGGGTGAATCGGGTGGTTTACGACATCAGTTCCAAGCCCCCGGCTACCATAGA
ATGGGAATAA

Protein sequence :
MQNNVLILDFGSQYTQLIARRVRELNIFCEIKPYNNLPGDLDGYKAVILSGSPFSTRSDDAPHPDLSRIKGHKPILAICY
GAQYIAHFNGGNVAPSKTREYGRAKLAHVAQDPFLKDVPVGSQVWMSHSDTIQQLPDGAVLLASTHDVPNAAFKMPDERI
YGIQFHPEVYHTTAGSLILRNFLVDIAGLEQTWTPAAFVETTVAELKEKIGTEKVILGLSGGVDSTVAAMLLHRAIGKHL
HCIFVNNGLLRKNEFEEVLHQYKDMGLNIKGVDASARFLDALEGESDPEKKRKIIGRVFIEVFDDEAHLVEDAKWLGQGT
IYPDVIESVSATGGPSATIKSHHNVGGLPDFMKLKVVEPLKMLFKDEVRRVGASLDIPAERLGRHPFPGPGLAIRILGDI
TREKVAILQEVDHIFINGLREWGLYDKIWQAGAMLLPVNSVGVMGDERTYEKCVALRAVESTDGMTADWVNLPYEFLQKT
SNDIINKVPGVNRVVYDISSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 2e-105 47
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 1e-105 47
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 1e-105 47
guaA NP_938969.1 GMP synthase Not tested Not named Protein 2e-107 47