Gene Information

Name : Dtox_0815 (Dtox_0815)
Accession : YP_003190346.1
Strain : Desulfotomaculum acetoxidans DSM 771
Genome accession: NC_013216
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : -
Position : 830229 - 831980 bp
Length : 1752 bp
Strand : +
Note : TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; PEP-utilising protein mobile region; Pyruvate kinase alpha/beta; KEGG: bha:BH3163 pyruvate kinase

DNA sequence :
GTGCGCCGAACAAAGATCGTTTGTACTATAGGACCAGCCTGCGAGGATGTGGAAATATTAAAAAAAATGATGCAGGCAGG
TATGAATGTAGCCAGACTTAATTTTTCTCACGGTACCTATGAAGAGCACGAAAAGAGAATTAAACTGGTGCGACAGGCTG
CCATTGAGGGAGGGTATAATATAGCCCTGCTTTTAGACACCAAGGGACCGGAAATTAGAATTGGCAAGTTCAAAGAGGAA
CCTGTTACTTTAAAAGAGGGTAAAAAGCTTGTTTTGACTACTGAAGAAATACTGGGAGACAGTGAACATATACATATTAC
TTATTCAGGATTGCCGGCAGATGTTGAGCCGGGCAACACTATTTTGATTGCGGACGGTTTAATAGAATTAAAGGTTCTTA
GCACTTCCAAGAAGGAAATTACCTGTGAGATAGTCAACGGCGGTCAACTCACCGGTCAAAAAGGGGTCAACGTACCGGGG
GTAAAGGTAAACCTGTCAGCTATGACAGAGCAGGATATTTCCGATTTGAAATTTGGCATCAAACAAAATATGGATTTTAT
TGCTGCTTCTTTTGTGCGCAAGACCTCTGATGTGCTGGCTATACGTGAGGTATTGGAGGAAGCGGGAGCTGATCTGGATA
TTATCGCTAAGATAGAAAATCGGGAAGGTGTGGATAATGTTTCTGATATCATCAAGGTTGCCGATGGTATTATGGTAGCC
AGAGGTGATTTGGGAGTAGAGATACCTGCCGAAGAGGTTCCTTTGCTGCAAAAGAGAATTATCGAAAAGTGTAACAGGCT
TGGAAAGCCGGTGATTACCGCTACCCAAATGCTGGAGTCCATGATACAAAATCCCCGTCCAACCAGAGCTGAAGCCAGTG
ATGTGGCCAATGCCATTTTTGACGGGACAGATGCCATCATGCTGTCGGGGGAAACCGCTATTGGCAAACACCCTGTGGAA
GCCGTCAAAACTATGGCCAGGATAGCGGAATGCTCGGAACAGTCACTTAATTATGAAGAAATTTTAAGTAAAAAAAGACA
GGTGCAGACCCGTACCGTAACGGATTCGATAAGTTATGCCACCTGTGCAATGGCCCAGGATTTGGGGGCAGCGGCCATTA
TAACGGCCACACAGACCGGTTATACCTCCATTATGGTTTCTAAATATCGTCCCAAGGCACCGGTTATAGCGGTAACGCCT
GTAGAGAGCATATCCAGAAAAATGGCTTTGGTCTGGGGGGTTAAATCAATCTTGACCGTGCCAACGAAAACCACTGATGA
GATGATTTCAACAGCGGTTAATTTTACGCTGGCTGCCGGTTTAATTAAGTCAGGTGATCTGCTGGTAATTACCGCCGGTG
TTCCGGTAGGTATACACGGCACGACTAATTTAATCAGAGTTCACACTGTGGGAGATATCCTGGCCAGGGGCACCGGTATA
GGTGCGCGTGCTGTTACCGGTAAAGTGAGAATTGTGCGTACGGTAAAGGATGCCCAGGAAAATGTTCAGCAGGGCGATAT
TCTGGTGGCCGAGTCGACTGATAGGGATTATATGCCGGCTATACAGAAGGCGGGAGCTATAATTACTGAAGTAGGAGGTT
TAACTTCACACGCTGCTATTGTTGGCCTGCAGTTTGGCATACCGGTGATTGTCGGAGTTGACGGGGCGGTAGGTATTCTG
CCTGAAGGGCAGATTGTTACGGTAGACGGGCGCAGAGGCCTGATCTATAGCGGTGAGGCCAGGGTATTATAA

Protein sequence :
MRRTKIVCTIGPACEDVEILKKMMQAGMNVARLNFSHGTYEEHEKRIKLVRQAAIEGGYNIALLLDTKGPEIRIGKFKEE
PVTLKEGKKLVLTTEEILGDSEHIHITYSGLPADVEPGNTILIADGLIELKVLSTSKKEITCEIVNGGQLTGQKGVNVPG
VKVNLSAMTEQDISDLKFGIKQNMDFIAASFVRKTSDVLAIREVLEEAGADLDIIAKIENREGVDNVSDIIKVADGIMVA
RGDLGVEIPAEEVPLLQKRIIEKCNRLGKPVITATQMLESMIQNPRPTRAEASDVANAIFDGTDAIMLSGETAIGKHPVE
AVKTMARIAECSEQSLNYEEILSKKRQVQTRTVTDSISYATCAMAQDLGAAAIITATQTGYTSIMVSKYRPKAPVIAVTP
VESISRKMALVWGVKSILTVPTKTTDEMISTAVNFTLAAGLIKSGDLLVITAGVPVGIHGTTNLIRVHTVGDILARGTGI
GARAVTGKVRIVRTVKDAQENVQQGDILVAESTDRDYMPAIQKAGAIITEVGGLTSHAAIVGLQFGIPVIVGVDGAVGIL
PEGQIVTVDGRRGLIYSGEARVL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 6e-94 49
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 3e-94 49
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 3e-94 49
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 1e-93 49

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Dtox_0815 YP_003190346.1 pyruvate kinase VFG0479 Protein 1e-94 49