Gene Information

Name : Dtox_0691 (Dtox_0691)
Accession : YP_003190228.1
Strain : Desulfotomaculum acetoxidans DSM 771
Genome accession: NC_013216
Putative virulence/resistance : Virulence
Product : FliI/YscN family ATPase
Function : -
COG functional category : N : Cell motility
COG ID : COG1157
EC number : 3.6.3.14
Position : 707105 - 708430 bp
Length : 1326 bp
Strand : +
Note : KEGG: bha:BH2455 flagellum-specific ATP synthase; TIGRFAM: ATPase, FliI/YscN family; PFAM: H+transporting two-sector ATPase alpha/beta subunit central region; H+transporting two-sector ATPase alpha/beta subunit domain protein; SMART: AAA ATPase

DNA sequence :
ATGAAGATGAGTGAGATCATTATTGATTTTGCACGTTGGAGCCGCAGGGTGCGGAAAAGCCGTGTAGCTGTTGTCAGCGG
TGAGGTAACCAGGGTGGTGGGGCTTACTGTTGAGGTTGTGGGTATAAAAGCCTCAATAGGGGAAGTTTGCCATGTTATTG
TGCCGGGGCGCAGCCGGCCTATTGTCGCTGAAGTAGTGGGTTTTATGCAGGGTGCGTCTATATTGATGCCGCTGGGTGAA
TTACAGGGTATACAGCCGGGCAACCAAGTTGTACCTACGGGACGGAACCTAACCGTTGAGGTTAGCGATGATATGCTTGG
TTCTGTATTGGATGGTCTGGGCAGACAGATTGGAGGCAAAACCGCGGGAGAGCAAAAGACTAAGTTTCCGGTTGATAATC
AACCTCCTAACCCGTTGACCAGACAGCGTATAGCTCAGGTGCTGCCGACAGGCGTGCGGGCTATCGATTCAGTGCTTACA
TGTGGTCAGGGACAGCGTATCGGCATTTTTGCCGGGAGCGGTGTAGGAAAGAGCACTTTGCTGGGCATGATTGCTAAGTA
TGGTAAAGCTGATGTGAACGTTATCGGTCTGATAGGGGAACGGGGACGGGAGGTTAAGGATTTTATTGAGACTGATCTGG
GGGAAGAAGGTTTAAGCCGTTCCGTGGTAGTGGCTGCTACCTCTGATCAACCGGCTTTAATCCGCCTGAAAGGTGCTATG
GTGGCAACAGCTTTGGCAGAGTATTTCAGAAACAAGGGCCTGAATGTGATGCTGCTGATGGATTCCGTAACCCGTTTTGC
TATGGCTCAGCGCGAGGTTGGTCTGGCTGTTGGAGAGCCTCCGGCTACTAAGGGATATACGCCTTCTGTTTTCGCACTGC
TGCCGAAGCTGCTGGAGAGATCGGGCATGTCGGTTGAGGGATCTATTACCGCCTTTTACACTGTGCTGGTTGACGGTGAC
GATATGAATGAGCCGATTGCGGACGCGGTGAGAGGAATATTGGACGGGCACATAGTTCTTACCAGACGGCTGGCAGCTAA
GAACCATTATCCTGCCATTGATGTTCTGTCCAGTGTAAGCCGGGTAATGTCCGATATTGTAAATCCGGAGCATTTATCCC
GGGCAGCCAGGCTTAGGGAACTATTGTCGACTTATTTACAGGCTGAAGATTTGATCAGTATAGGTGCCTATAACTTTGGA
GCAAATCCCAAGATTGACGATGCTATTCGACACTATGACAATATCATTGAATTTTTGCGACAGCACCCTGAAGAGCCGTA
TGAATTCTCCGAAACAATTGATTGGCTGCGCAGGTTGGGCGATTAG

Protein sequence :
MKMSEIIIDFARWSRRVRKSRVAVVSGEVTRVVGLTVEVVGIKASIGEVCHVIVPGRSRPIVAEVVGFMQGASILMPLGE
LQGIQPGNQVVPTGRNLTVEVSDDMLGSVLDGLGRQIGGKTAGEQKTKFPVDNQPPNPLTRQRIAQVLPTGVRAIDSVLT
CGQGQRIGIFAGSGVGKSTLLGMIAKYGKADVNVIGLIGERGREVKDFIETDLGEEGLSRSVVVAATSDQPALIRLKGAM
VATALAEYFRNKGLNVMLLMDSVTRFAMAQREVGLAVGEPPATKGYTPSVFALLPKLLERSGMSVEGSITAFYTVLVDGD
DMNEPIADAVRGILDGHIVLTRRLAAKNHYPAIDVLSSVSRVMSDIVNPEHLSRAARLRELLSTYLQAEDLISIGAYNFG
ANPKIDDAIRHYDNIIEFLRQHPEEPYEFSETIDWLRRLGD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lscN AAO18044.1 LscN Virulence TTSS locus Protein 2e-101 56
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 1e-90 54
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 3e-94 53
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-94 53
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-95 53
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 2e-94 53
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 6e-95 53
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 1e-95 53
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 1e-95 53
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 9e-92 52
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 9e-92 52
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 5e-85 52
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 8e-86 52
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 5e-85 52
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 1e-85 52
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 6e-86 52
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 4e-81 50
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 4e-81 50
hrcN AAB06001.1 HrcN Virulence Hrp PAI Protein 2e-80 50
escN AAC31513.1 L0034 Virulence LEE Protein 1e-80 50
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 1e-81 50
escN CAC81862.1 EscN protein Virulence LEE II Protein 9e-82 50
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 1e-80 50
unnamed AAL06369.1 EscN Virulence LEE Protein 2e-79 50
escN YP_003236088.1 translocator EscN Virulence LEE Protein 4e-80 50
escN NP_290268.1 hypothetical protein Virulence LEE Protein 2e-80 50
escN AAK26715.1 EscN Virulence LEE Protein 2e-81 50
ECs4568 NP_312595.1 EscN Virulence LEE Protein 2e-80 50
escN AAL57542.1 EscN Virulence LEE Protein 2e-81 50
escN AAC38383.1 EscN Virulence LEE Protein 2e-80 50
escN CAI43874.1 EscN protein Virulence LEE Protein 1e-81 49
escN YP_003223475.1 translocator EscN Virulence LEE Protein 1e-81 49
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 3e-79 48
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 8e-81 48
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 5e-81 48
hrcN AAR25633.1 type III secretion cytoplasmic ATPase HrcN Not tested Not named Protein 4e-74 48
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 3e-79 48
hrcN ABQ88354.1 HrcN Virulence Hrp PAI Protein 3e-74 46
hrpJ4 AAA81942.1 HrpJ4 Virulence Hrp PAI Protein 3e-74 46
hrcN AAT96258.1 HrcN Virulence S-PAI Protein 3e-76 46
hrcN AAT96299.1 HrcN Virulence S-PAI Protein 1e-76 46
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 1e-76 46
hrcN ABA47275.1 HrcN Virulence S-PAI Protein 2e-80 46
ysaN AAS66842.1 YsaN Not tested SSR-1 Protein 7e-71 44
ECs3730 NP_311757.1 ATP synthase SpaL Not tested LIM Protein 6e-69 44
spaI NP_806497.1 ATP synthase SpaL Virulence SPI-1 Protein 5e-66 43
invC NP_461815.1 ATP synthase SpaL Virulence SPI-1 Protein 5e-66 43
invC YP_217813.1 ATP synthase SpaL Virulence SPI-1 Protein 5e-66 43
spaI NP_457288.1 secretory apparatus ATP synthase (associated with virulence) Virulence SPI-1 Protein 5e-66 43
invC AAS66861.1 InvC Not tested SSR-2 Protein 2e-71 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Dtox_0691 YP_003190228.1 FliI/YscN family ATPase VFG2144 Protein 5e-99 56
Dtox_0691 YP_003190228.1 FliI/YscN family ATPase VFG0192 Protein 3e-101 55
Dtox_0691 YP_003190228.1 FliI/YscN family ATPase VFG0048 Protein 1e-100 55
Dtox_0691 YP_003190228.1 FliI/YscN family ATPase VFG0390 Protein 5e-97 54
Dtox_0691 YP_003190228.1 FliI/YscN family ATPase VFG1254 Protein 1e-95 53
Dtox_0691 YP_003190228.1 FliI/YscN family ATPase VFG0515 Protein 5e-86 52
Dtox_0691 YP_003190228.1 FliI/YscN family ATPase VFG2331 Protein 5e-86 52
Dtox_0691 YP_003190228.1 FliI/YscN family ATPase VFG2499 Protein 1e-86 52
Dtox_0691 YP_003190228.1 FliI/YscN family ATPase VFG0730 Protein 1e-80 50
Dtox_0691 YP_003190228.1 FliI/YscN family ATPase VFG0812 Protein 7e-81 50
Dtox_0691 YP_003190228.1 FliI/YscN family ATPase VFG1778 Protein 1e-71 45
Dtox_0691 YP_003190228.1 FliI/YscN family ATPase VFG1008 Protein 7e-68 44
Dtox_0691 YP_003190228.1 FliI/YscN family ATPase VFG2459 Protein 4e-75 44
Dtox_0691 YP_003190228.1 FliI/YscN family ATPase VFG0555 Protein 2e-66 43