Gene Information

Name : Dtox_4349 (Dtox_4349)
Accession : YP_003193635.1
Strain : Desulfotomaculum acetoxidans DSM 771
Genome accession: NC_013216
Putative virulence/resistance : Unknown
Product : replicative DNA helicase
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0305
EC number : -
Position : 4526496 - 4527821 bp
Length : 1326 bp
Strand : -
Note : TIGRFAM: replicative DNA helicase; PFAM: DnaB domain protein helicase domain protein; KEGG: bha:BH4029 replicative DNA helicase

DNA sequence :
ATGTTAGATAAAATACCGCCTCAGAACATGGAAGCTGAGCAATCCGTAATTGGTTCTGTTTTTTTAGACAAAGAAGCGAT
ATATAAGGTAATGCGCATTATAAGTCCAGATGATTTTTACAGTGAGAGCCATAAGTTAATTTATGAAGTTATTTTAGATT
TGAACGATAATTCAGCTGCAATTGACTTATTAACTGTAACAGAAAGCTTGCGCCAGAGAGGCCATTTGGATAAAATTGGC
GGAGTGACCTATATTGCCTCTTTGCCCGGTATGGTGCCTACTTCTGCAAATGTAGAGTACTATGCCAAAATTGTAGAAGA
GAAATCACTTCTCAGAACTTTAATCAGCCTGGCCTCCAGAATAGCCAATATGAGCTATGAAGGCAGTGAGAATGCACAGC
GGTTGATGGATGAAGCCGAGCGAATGATTTTGGAATTGAGCAGCAGGAGATCTGCTTCCGCATTTACACCGATTAAAGAG
ATTTTATTAAAGATTCTTGAGTATATCGACTATTTAAGTGAAAATAAAGGTGCTGTAACAGGTGTTTCCACAGGTTTTGT
CGATCTTGACTCTATTTGCAGCGGTTTTCAAAAAGGCGATTTAATGATTCTGGCGGCTCGCCCAAGTATGGGTAAAACCA
GCCTTGGTCTAAATGTAGCTCAACACGCTGCCCTGCACCGCAAAATTCCGGTGGCCTTTTTCAGTCTGGAAATGTCTAAA
GAACAGCTGGTTCAGAGAATGCTGTGTGCCGAAGCCATGGTGGATCAACATAAATTGCGCATAGGTAATTTAAAAGAAGA
AGATTGGGAAAAAATAAACAATACTGCGGCCAAGCTGTCTGGAATACCCGTTTTTATTGATGACACTCCTGCTATATCCA
TAAGAGAATTGAGAGCTAAAGCCAGACGTTTACAAGCTGAACACGGCTTAGGGCTGGTGGTAATAGATTATCTGCAGTTG
ATGCAGGCGGGAAAGAAAACAGATAACCGGCAGCAGGAAATTGCGGAAATTTCCCGTTCACTAAAGAGTTTAGCAAAAGA
GATGAAGGTTCCGGTTTTGGCTCTGGCTCAACTTAGCCGTTCTGTGGAGCAGCGGCAGGATAAGAAGCCTTTACTTTCTG
ATCTCAGAGAAAGCGGCAGTTTAGAACAAGATGCCGATATGGTTATGTTTATCTACCGGGATGAGTACTATAATGCCGAA
AGTGAAAAGAAGGGAATTGCTGAGATAATAGTGGCCAAACAGAGAAACGGGCCGACCGGTATTGTTGAACTGGGTTTTTT
AAAGGAATATACTAGATTTGTTAATTTGGCCAAGCGAGCTGACTAA

Protein sequence :
MLDKIPPQNMEAEQSVIGSVFLDKEAIYKVMRIISPDDFYSESHKLIYEVILDLNDNSAAIDLLTVTESLRQRGHLDKIG
GVTYIASLPGMVPTSANVEYYAKIVEEKSLLRTLISLASRIANMSYEGSENAQRLMDEAERMILELSSRRSASAFTPIKE
ILLKILEYIDYLSENKGAVTGVSTGFVDLDSICSGFQKGDLMILAARPSMGKTSLGLNVAQHAALHRKIPVAFFSLEMSK
EQLVQRMLCAEAMVDQHKLRIGNLKEEDWEKINNTAAKLSGIPVFIDDTPAISIRELRAKARRLQAEHGLGLVVIDYLQL
MQAGKKTDNRQQEIAEISRSLKSLAKEMKVPVLALAQLSRSVEQRQDKKPLLSDLRESGSLEQDADMVMFIYRDEYYNAE
SEKKGIAEIIVAKQRNGPTGIVELGFLKEYTRFVNLAKRAD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed ABR13456.1 replicative DNA helicase Not tested PAGI-5 Protein 3e-74 43
PMI2640 YP_002152342.1 DNA helicase Not tested Not named Protein 6e-73 43
t4227 NP_807829.1 DNA helicase Not tested SPI-7 Protein 7e-72 42
STY4522 NP_458617.1 DNA helicase Not tested SPI-7 Protein 7e-72 42
dnaB2 YP_001007676.1 putative DNA helicase Not tested YAPI Protein 7e-76 41
dnaB2 YP_001402701.1 replicative DNA helicase Not tested YAPI Protein 5e-77 41
api2 CAF28476.1 putative DNA binding protein with DNA-dependent ATPase activity Not tested YAPI Protein 1e-77 41
dnaB CAI36044.1 replicative DNA helicase DnaB Not tested PPHGI-1 Protein 2e-63 41