Gene Information

Name : hemC (Dtox_1251)
Accession : YP_003190756.1
Strain : Desulfotomaculum acetoxidans DSM 771
Genome accession: NC_013216
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 1268076 - 1269005 bp
Length : 930 bp
Strand : +
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
ATGAGAGAAATTGTAGTCGGAACCAGGGATAGTCAACTGGCTCTCTGGCAGGCTAACTGGGTTGTGGACAGATTGCGTGA
GCGTAACCCCGGTTATAGTTTTCGCATTCAGGGTATTAAAACCCATGGTGATAATATTCTTGATGTGGCCCTGGCCAAAA
TAGGCGATAAGGGTCTTTTTACTAAAGAGCTGGAAGTGGCGTTACTGAGTGATGAAATTGATTTAGCGGTTCATAGCATG
AAGGATCTGCCCACAGATCTTCCTGGCGGGCTTGCTGTAGGCGCAGTTTGTGAAAGGGAATATCCGGGTGACGTTTTGGT
ATCATCACAGGGTTATGTTCTGGATAAGTTGCCTGAAGGAGCTGTTATTGGTACCAGTAGTTTGAGACGTACAGCCCAAC
TGCTTCACTACAGGCAGGATTTAAGAATAGTTAATATCAGAGGCAACCTGAATACCCGTTTAAGAAAAATGGATGAAGAA
AAGCTGGATGGTGTTGTACTGGCTTATGCCGGGATTCAGAGACTTGGTTTGAAGGATAGAATCACAGAGCGGATTCCTAT
GGAAATATGTTTGCCCGCAGTGGGTCAGGGTTCCATAGGCATTGAAATTCGTCATTTAGATGAGGAAATTATGGATATTG
TGGAAACTATAGAGCACAGACCGTCTAGGATCGCTGTTAGTGCTGAAAGAAATTTTCTGAAAAGATTAGAAGGCGGCTGT
CAGGTGCCAATCGGGGCATATGGCCTGGTAATCGGTAATGAAATTAAATTCGAAGGTTTGATTGCCAGTTTAGATGGCAA
GCATCTGGTTCGTGATGTTATAGCCGGGCCTGTTAATGAAGCTGCCAAGATTGGAGTTAAGCTGGCGGAGAGCCTGTTGA
AAAAAGGCGGCAGGGAAATATTGCGGGCTGTACGACAGGAGAATTGTTAA

Protein sequence :
MREIVVGTRDSQLALWQANWVVDRLRERNPGYSFRIQGIKTHGDNILDVALAKIGDKGLFTKELEVALLSDEIDLAVHSM
KDLPTDLPGGLAVGAVCEREYPGDVLVSSQGYVLDKLPEGAVIGTSSLRRTAQLLHYRQDLRIVNIRGNLNTRLRKMDEE
KLDGVVLAYAGIQRLGLKDRITERIPMEICLPAVGQGSIGIEIRHLDEEIMDIVETIEHRPSRIAVSAERNFLKRLEGGC
QVPIGAYGLVIGNEIKFEGLIASLDGKHLVRDVIAGPVNEAAKIGVKLAESLLKKGGREILRAVRQENC

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 1e-63 47
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 1e-63 47