Gene Information

Name : guaA (APA01_22710)
Accession : YP_003188765.1
Strain : Acetobacter pasteurianus IFO 3283
Genome accession: NC_013209
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 2467958 - 2469559 bp
Length : 1602 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGTCTGTTGATGCCACCCCGCCTGTTTCGTCTTCCAAGCTGGATGAATCCTTGCACCATGACCGTATTCTGATTCTGGA
TTTCGGAAGTCAGGTTACGCAGCTTATTGCCCGCCGTGTGCGCGAAAGTGGTGTGTATTGTGAAATCTGGCCATTTACGG
CAGATGCTGAACGGATTCGTCAGTTTTCACCCCGTGGTATTATTCTTTCTGGTGGCCCTGCCAGCGTAAACAACCCGGAT
GCCCCGCGTGTGCCGGATGTGGTGTTTGAAATGGCCGTGCCTGTGCTGGGTATCTGCTATGGTCAGCAGGCCATGTGCAA
GCAGTTGGGCGGGCAGGTTGAAAGCGGGGATCACCGTGAATTTGGCCGCGCTTTTGTTGATATTGTAGAAGATTGCGCAC
TGTTCCGTGGTGCATGGGCACGTGGTGGCCGTGAACAGGTATGGATGAGCCACGGTGACCGCGTAGTGGAGCTTCCCCCC
GGTTTCCGTACCGTTGCCGTGAGTGAAGGTGCACCGTTTGCTGTTATCGCAGATGAAGGTCGCCGCCTGTATGGTGTGCA
GTTCCACCCGGAAGTGGTGCACACGCCGCATGGGGCAGCACTGCTTAAGAACTTTACCCATAATGTTGCAGGCTGCTCCG
GCACATGGACGATGGCTGGTTTCCGTGAAATGGAAATTGCCCGGATTCGTGAACAAGTGGGTGATGGCAAGGTTATCTGC
GGCCTGTCCGGTGGTGTGGATTCTTCCGTAGCTGCTGTGTTGATTCATGAAGCCATTGGCGATCAGCTTACCTGTATTTT
TGTTGATCACGGTATGCTGCGTGCTGGCGAAGCCGATGATGTGATCAAAACATTCCGCGGCCAGTTTAACATCCAGCTCG
TGCATCGCGATGCTTCAGACATCTTCCTGAAAGAATTGGATGGCGTCACAGATCCGGAAATCAAGCGGAAAACTATTGGC
CGCTTATTTGTTGAAGTGTTTGAAGAAGAAGCCACAAAACTGGGTGGGGCGCAGTTCCTTGCGCAGGGCACGCTTTATCC
AGATGTGATCGAGAGTGTCAGCTTTACGGGTGGCCCTTCCGTTACCATCAAGTCTCACCACAATGTGGGTGGCTTGCCGG
ATCGGATGAACATGAAGCTGGTCGAACCGCTGCGCGAGCTCTTTAAGGATGAAGTCCGCGATCTGGGGCGTGAACTGGGG
ATTCCCGAAATTATTGTCGGGCGTCATCCGTTCCCAGGGCCGGGTCTGGCTATTCGTATTCCGGGCAATATCACGCGGGA
AAAACTGGATCTGCTTCGTAAGGTGGATTCCGTGTTTCTGGAAGAAATTCGGGCTGCTGGACTGTATGATGCCATCTGGC
AGGCCTTTGCCGTGTTGCTGCCAGTGCGCACCGTTGGTGTGATGGGTGATGGCCGCACGTATGATCAGGCCTGCGCCCTG
CGTGCTGTCACCAGTACAGATGGCATGACAGCAGATGTTTACCCGTTTGACATGGGCTTCCTGACCCGTGTTGCTGGGCG
TATCGTGAACGAAGTGCGTGGGATTAACCGCGTAACGTATGACATCACGTCCAAGCCACCGGGCACGATTGAGTGGGAAT
AA

Protein sequence :
MSVDATPPVSSSKLDESLHHDRILILDFGSQVTQLIARRVRESGVYCEIWPFTADAERIRQFSPRGIILSGGPASVNNPD
APRVPDVVFEMAVPVLGICYGQQAMCKQLGGQVESGDHREFGRAFVDIVEDCALFRGAWARGGREQVWMSHGDRVVELPP
GFRTVAVSEGAPFAVIADEGRRLYGVQFHPEVVHTPHGAALLKNFTHNVAGCSGTWTMAGFREMEIARIREQVGDGKVIC
GLSGGVDSSVAAVLIHEAIGDQLTCIFVDHGMLRAGEADDVIKTFRGQFNIQLVHRDASDIFLKELDGVTDPEIKRKTIG
RLFVEVFEEEATKLGGAQFLAQGTLYPDVIESVSFTGGPSVTIKSHHNVGGLPDRMNMKLVEPLRELFKDEVRDLGRELG
IPEIIVGRHPFPGPGLAIRIPGNITREKLDLLRKVDSVFLEEIRAAGLYDAIWQAFAVLLPVRTVGVMGDGRTYDQACAL
RAVTSTDGMTADVYPFDMGFLTRVAGRIVNEVRGINRVTYDITSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 9e-137 55
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 1e-136 54
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 1e-136 54
guaA NP_938969.1 GMP synthase Not tested Not named Protein 5e-118 51