Gene Information

Name : Aaci_0900 (Aaci_0900)
Accession : YP_003184329.1
Strain : Alicyclobacillus acidocaldarius DSM 446
Genome accession: NC_013205
Putative virulence/resistance : Resistance
Product : cystathionine gamma-synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 2.5.1.48
Position : 974362 - 975528 bp
Length : 1167 bp
Strand : +
Note : PFAM: Cys/Met metabolism pyridoxal-phosphate- dependent protein; KEGG: geo:Geob_1413 cystathionine gamma-synthase

DNA sequence :
TTGAAGATCGAATCGAAGCTGGCCCAGATTGGGAATCGCCAGGATCCCGGGACCGGAGCCGTGTCTGCTCCAATTTACCA
CTCGACGACATACGCTCATCCGGCGCTCGGCCAGAGCACTGGATTCGATTACACGCGGACGCTCAATCCGACCCGCAAGA
TTCTCGAGGACGCCATCGCGGATCTCGAAGGCGGCGTTCGCGGATTCGCGTTTTCCTCCGGCATGGCCGCGGTCCACGCC
GTCTTTTCCCTGTTTTCCCCGGGCGATCACGTCATCGTCTCGAGCGATCTGTACGGCGGCACGTATCGGGTGCTCGAGCA
CATCTTTCGCCCGCTTGGCATCGAGGCCACCTATGTGCACACGGGCCACCTCGAGGAGGTGGAGGCCGCCGCGCGGGACA
CCACGCGCGCGTTGTTCATCGAAACGCCCACCAATCCGACCATGCAAATCACCGACATCGCGGCGGCAAGCCTCTTCGCA
AGGAGGCGCGGCTGGCTCACCATCGTGGACAACACGTTCATGACGCCGTACTTCCAGCGGCCCATTGAGTTGGGCGCGGA
CATCGTGGTTCACTCGGCCACGAAGTTTCTGGGCGGACACAACGACGTGCTCGCCGGCCTCGTGGTGGCGAAATCGGACG
AGATCGCCGAGCGGCTGTACTTCGTCCAGAACTCCATCGGGGCCGTGCTCGGACCGCAGGACGCGTGGCTCCTCATGCGG
GGCATGAAGACGCTCGCCATACGCATGGAGCGGTGCGCGATGAACGCGAGCGCCATCGCAGCGTGGCTCGACGCGCGCGA
CGACATCGTGAAGGTTTACTATCCCGGCCTCGATACGCATCCGGGGAAGTCCATCTGCTCGAAGCAGGCGTCTGGCTTCG
GGGGCATGGTGTCGTTCGAGGTGCTGGACGCGCGGATGGTGCCGTTCATCCTCGAGCATTTGAAGCTCGTCACGTTCGCG
GAGAGTCTCGGCGGCGTCGAGACGCTCATCACCTATCCCTCCCGGCAGACCCACGCCGACATTCCGGAGGAGATCCGAGA
GAAGGTGGGCGTCACGGACAGGCTGCTGCGGCTGTCGGTGGGCATCGAGCATATTGGGGATCTCATCGACGATCTGAGCC
AAGCGCTCGATCACGCCGCGGAGCAGGTGCTCTCCCGCAGGCGGTGA

Protein sequence :
MKIESKLAQIGNRQDPGTGAVSAPIYHSTTYAHPALGQSTGFDYTRTLNPTRKILEDAIADLEGGVRGFAFSSGMAAVHA
VFSLFSPGDHVIVSSDLYGGTYRVLEHIFRPLGIEATYVHTGHLEEVEAAARDTTRALFIETPTNPTMQITDIAAASLFA
RRRGWLTIVDNTFMTPYFQRPIELGADIVVHSATKFLGGHNDVLAGLVVAKSDEIAERLYFVQNSIGAVLGPQDAWLLMR
GMKTLAIRMERCAMNASAIAAWLDARDDIVKVYYPGLDTHPGKSICSKQASGFGGMVSFEVLDARMVPFILEHLKLVTFA
ESLGGVETLITYPSRQTHADIPEEIREKVGVTDRLLRLSVGIEHIGDLIDDLSQALDHAAEQVLSRRR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 6e-88 49
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 4e-89 49
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 2e-64 43

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Aaci_0900 YP_003184329.1 cystathionine gamma-synthase BAC0207 Protein 3e-60 41