Gene Information

Name : Aaci_0392 (Aaci_0392)
Accession : YP_003183840.1
Strain : Alicyclobacillus acidocaldarius DSM 446
Genome accession: NC_013205
Putative virulence/resistance : Unknown
Product : GMP synthase large subunit
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 446952 - 448481 bp
Length : 1530 bp
Strand : +
Note : TIGRFAM: GMP synthase, large subunit; GMP synthase, small subunit; PFAM: glutamine amidotransferase class-I; GMP synthase domain protein; KEGG: glo:Glov_1901 GMP synthase

DNA sequence :
ATGCATGAACTTGTGGCCGTCCTCGACTTCGGAGGCCAGTACAACCAGCTGATTGCACGGCGCATCCGCGAGCTCGGCGT
GTACTCCGAGCTTCTGCCCCACACCACATCGGCCGAAGCGCTGAAGCAGCGCCCGCTCAAGGGCATCGTCTTCTCCGGCG
GCCCGAAGAGCGTGTTTGCGGAAGGCGCGCCAGACGTCGATCACGCCGTGTTCGATCTCGGCGTCCCCATTCTCGGCATT
TGTTACGGCATGCAGCTCATGGCGAAGCGGTACCACGCGGACGTGGCACGCGGCGCCGTGCGCGAATACGGGCGGGCGTC
CATCGAGGTGAAGCCGGGCGCTGAGCTGTTTCGCGGCCTGCCGGATCGCCAGGGCGTGTGGATGAGCCACAGCGACGTGG
TGACCAAGGTGCCCGAGGGCTTTCGCCTCGACGCGATCACCGACAACGGCGCCATCGCGGCCATGTCGAAGCCAGATGCG
CAGCTTTACGCCGTCCAATTTCACCCCGAGGTCCATCACAGCGATTACGGCACGGACCTTCTCCGCAACTTCCTATTCGA
CGTCTGCCGCTGCCGCGGGGATTGGACGATGCGCAACTTCATCGACGAGTCCATTGCCAGCATTCGCGAGCGAGTCGGCG
ACAAGCGCGTGCTCGTCGCCATCTCGGGCGGGGTCGATTCGTCGGTGGCGGCGGCGCTGGTGCATCGCGCCATTGGCCAT
CAGCTGACGGCCATGTTCGTCGATCACGGCCTCCTGCGCAAGGGCGAGAGCGACAGCGTCATGCAGAGCCTGCGGGACAA
GCTCGGCATCGACGTGGTGCGGGTGGACGCGAAGGAGCGGTTTCTGGGCCGCCTCGAGGGCGTAACCGATCCCGAGCGGA
AGCGGAAGATCATCGGCGAGGAATTCATCCGCGTGTTTGAGGAAGAGTCGGAGCGACTCGGCCCGTTCGACTACCTCGTG
CAGGGCACGCTCTACACCGACATCATCGAAAGCGGGACGCATACGGCGGCGACCATCAAGTCGCATCACAATGTGGGCGG
ACTGCCGGAAGACGTCCGGTTTGAGATCATCGAGCCGCTGCGCGATCTGTTCAAGGACGAGGTGCGCCGCCTCGGCGAAG
CGCTGGGCCTGGCGCCCGAGATCGTCTGGCGGCAGCCGTTCCCGGGGCCAGGGCTTGCCATCCGCATCATCGGCGAGGTG
ACGGAAGAGAAACTGCATCTCGTGCGCGAGTCGGACGCCATTTTGCGCGAGGAGATCGCGAAGGCGGGGCTGGAGCGCGA
GATCTGGCAGTACTTCACCGTGCTGACCGGCAACCGCACCGTGGGCGTGATGGGCGACGAGCGGACGTACGCCTACACGC
TCGCCGTCCGCGCGGTCCTGTCGCAGGAGGGCATGACGGCGGATTTCGCGCGTATTCCCTGGGACGTCCTGGCGGCCATT
TCGACGCGCATTGTCAACGAGGTCCCGGGCATCAACCGCGTCGTGTACGACATCACGTCCAAGCCGCCCGCGACCATCGA
GTGGGAGTGA

Protein sequence :
MHELVAVLDFGGQYNQLIARRIRELGVYSELLPHTTSAEALKQRPLKGIVFSGGPKSVFAEGAPDVDHAVFDLGVPILGI
CYGMQLMAKRYHADVARGAVREYGRASIEVKPGAELFRGLPDRQGVWMSHSDVVTKVPEGFRLDAITDNGAIAAMSKPDA
QLYAVQFHPEVHHSDYGTDLLRNFLFDVCRCRGDWTMRNFIDESIASIRERVGDKRVLVAISGGVDSSVAAALVHRAIGH
QLTAMFVDHGLLRKGESDSVMQSLRDKLGIDVVRVDAKERFLGRLEGVTDPERKRKIIGEEFIRVFEEESERLGPFDYLV
QGTLYTDIIESGTHTAATIKSHHNVGGLPEDVRFEIIEPLRDLFKDEVRRLGEALGLAPEIVWRQPFPGPGLAIRIIGEV
TEEKLHLVRESDAILREEIAKAGLEREIWQYFTVLTGNRTVGVMGDERTYAYTLAVRAVLSQEGMTADFARIPWDVLAAI
STRIVNEVPGINRVVYDITSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 3e-157 63
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 4e-157 62
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 4e-157 62
guaA NP_938969.1 GMP synthase Not tested Not named Protein 4e-120 51