Gene Information

Name : Aaci_1392 (Aaci_1392)
Accession : YP_003184808.1
Strain : Alicyclobacillus acidocaldarius DSM 446
Genome accession: NC_013205
Putative virulence/resistance : Virulence
Product : FliI/YscN family ATPase
Function : -
COG functional category : N : Cell motility
COG ID : COG1157
EC number : 3.6.3.14
Position : 1447260 - 1448585 bp
Length : 1326 bp
Strand : +
Note : KEGG: xac:XAC0412 type III secretion system ATPase; TIGRFAM: ATPase, FliI/YscN family; PFAM: H+transporting two-sector ATPase alpha/beta subunit central region; H+transporting two-sector ATPase alpha/beta subunit domain protein; SMART: AAA ATPase

DNA sequence :
ATGGCGCGTGATCCGAGCTGGGTGGCCGAGGCGATTCGGGAGGTGGAGCGGAGGCACTTGGTACGCCGCGCGGGGCGCGT
CATGCGCGTCATTGGTCACATGCTCGAGGTTGCGGGGCCGACAGCCTCCCTTGGCGAATTGTGTGCACTGGGCCGGGATG
CGTCGGAAGGGCTGGGTGAGGTCATCGGATTTCACGAAGGGCGTCTCTATGTGGTTCCTCTGGGCCCGTTGCCGGAGGTA
TCCCCCGGAACGCCGGTTCGCTTTCTGGAGCGACAGTTTCGCATCCGCTGCGGGCCTGGCTTGGTCGGCCGGGTATTGAA
TGGACTCGGGGAGCCCATCGATGACCGAGGCCCCTTGGAAGGGCCGCTCGTGTGGCGGACCGTGGACGCGCCTGCCATCT
CGCCCCTTCGCCGGGGTCGCATCAGCTCACCCTACGCGACGGGCGTACGAGCCATCGACGCGCTGCTCACCATCGGCCGA
GGCCAGCGCGTCGGCCTGTTCGCGGGGAGCGGCGTGGGCAAAAGCACGTTGCTCAGCATGATGGCCCGCGGCGGTCGCGC
CGACGTGCACGTCATCGCGCTCGTCGGCGAGCGAGGGCGAGAGGTGAGGGAATTCTTAGAGGACGATCTCGGCGAAGAAG
GGATGAGGCGGAGCGTCGTGATCGTCGCCACCTCCGATGAGTCGGCGTACGTCCGAAGCAAGGCGGCCTTTGTGGCCACC
GCCATCGCCGAGCATTTTCGCGACGAAGGCATGCACGTGACGCTCATGATGGACTCGCTCACGCGTTTCGCGATGGCGGA
GCGCGAGGTGGGACTCGCCATGGGGGAGCCTCCGTCGTCCCGAGGGTACACGCCGAGCGTGTTCGCCAAGCTCCCTGTGC
TCCTCGAGCGCGCAGGCCCTGGACCCGTGGGCGCGATCACGGCCGTCTACACGGTCCTGGTCGAGGGCGACGATCTCAAC
GACCCCATCGCGGACGCCGTGCGAGGCATCCTGGATGGACATATCGTGCTTTCTCGCTCGCTCGCCAATCGAGGTCAGTT
TCCCGCCATCGACGTCCTCCAGAGTCTGTCGCGCCTGTTTCCGTCCATCGCGGACGAGGACCATCGCCGGGCGGCGGAGC
GCGTGCGGGAATGGATGGCGAGGTATGGCGAAATCGAGGACCTGTTCCGGATCGGCGCGTACCGGCAGGGAACGGATCCT
GCGGTGGATGAGGCCATCCAGCGCATGCCGGAGATCCTCGAGTTTCTCCGGCAAAAGAAGGGCGAAACGGTTGCATTCGA
AGAAGCCATCACGCAATTGTTGAACCTTGCGGGGGATCGGGAATGA

Protein sequence :
MARDPSWVAEAIREVERRHLVRRAGRVMRVIGHMLEVAGPTASLGELCALGRDASEGLGEVIGFHEGRLYVVPLGPLPEV
SPGTPVRFLERQFRIRCGPGLVGRVLNGLGEPIDDRGPLEGPLVWRTVDAPAISPLRRGRISSPYATGVRAIDALLTIGR
GQRVGLFAGSGVGKSTLLSMMARGGRADVHVIALVGERGREVREFLEDDLGEEGMRRSVVIVATSDESAYVRSKAAFVAT
AIAEHFRDEGMHVTLMMDSLTRFAMAEREVGLAMGEPPSSRGYTPSVFAKLPVLLERAGPGPVGAITAVYTVLVEGDDLN
DPIADAVRGILDGHIVLSRSLANRGQFPAIDVLQSLSRLFPSIADEDHRRAAERVREWMARYGEIEDLFRIGAYRQGTDP
AVDEAIQRMPEILEFLRQKKGETVAFEEAITQLLNLAGDRE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 3e-101 54
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 3e-100 53
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 5e-99 53
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 5e-99 53
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-99 53
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 8e-100 53
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 4e-100 53
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 1e-99 53
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 3e-100 53
lscN AAO18044.1 LscN Virulence TTSS locus Protein 2e-93 50
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 3e-86 48
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 3e-85 48
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 4e-85 48
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 4e-78 48
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 1e-79 48
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 8e-80 48
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 1e-76 47
hrcN AAR25633.1 type III secretion cytoplasmic ATPase HrcN Not tested Not named Protein 6e-74 47
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 3e-85 47
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 3e-85 47
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 3e-82 47
hrpJ4 AAA81942.1 HrpJ4 Virulence Hrp PAI Protein 7e-74 46
hrcN ABQ88354.1 HrcN Virulence Hrp PAI Protein 7e-74 46
hrcN AAB06001.1 HrcN Virulence Hrp PAI Protein 6e-79 46
escN AAC38383.1 EscN Virulence LEE Protein 4e-82 46
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 8e-82 46
escN AAC31513.1 L0034 Virulence LEE Protein 3e-82 46
escN YP_003236088.1 translocator EscN Virulence LEE Protein 4e-82 46
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 3e-82 46
escN NP_290268.1 hypothetical protein Virulence LEE Protein 4e-82 46
ECs4568 NP_312595.1 EscN Virulence LEE Protein 4e-82 46
escN CAI43874.1 EscN protein Virulence LEE Protein 1e-81 46
escN CAC81862.1 EscN protein Virulence LEE II Protein 7e-82 46
escN AAK26715.1 EscN Virulence LEE Protein 5e-82 46
escN AAL57542.1 EscN Virulence LEE Protein 5e-82 46
escN YP_003223475.1 translocator EscN Virulence LEE Protein 2e-81 46
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 7e-79 46
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 7e-79 46
hrcN AAT96299.1 HrcN Virulence S-PAI Protein 3e-80 45
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 2e-80 45
hrcN AAT96258.1 HrcN Virulence S-PAI Protein 2e-80 45
hrcN ABA47275.1 HrcN Virulence S-PAI Protein 2e-86 45
unnamed AAL06369.1 EscN Virulence LEE Protein 1e-80 45
ysaN AAS66842.1 YsaN Not tested SSR-1 Protein 1e-70 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Aaci_1392 YP_003184808.1 FliI/YscN family ATPase VFG2144 Protein 4e-102 54
Aaci_1392 YP_003184808.1 FliI/YscN family ATPase VFG0192 Protein 4e-99 54
Aaci_1392 YP_003184808.1 FliI/YscN family ATPase VFG0390 Protein 2e-92 50
Aaci_1392 YP_003184808.1 FliI/YscN family ATPase VFG0048 Protein 3e-96 49
Aaci_1392 YP_003184808.1 FliI/YscN family ATPase VFG1254 Protein 5e-94 49
Aaci_1392 YP_003184808.1 FliI/YscN family ATPase VFG2331 Protein 9e-84 48
Aaci_1392 YP_003184808.1 FliI/YscN family ATPase VFG0515 Protein 2e-85 48
Aaci_1392 YP_003184808.1 FliI/YscN family ATPase VFG2499 Protein 4e-84 48
Aaci_1392 YP_003184808.1 FliI/YscN family ATPase VFG0812 Protein 2e-82 46
Aaci_1392 YP_003184808.1 FliI/YscN family ATPase VFG0730 Protein 2e-82 46
Aaci_1392 YP_003184808.1 FliI/YscN family ATPase VFG2459 Protein 1e-70 43
Aaci_1392 YP_003184808.1 FliI/YscN family ATPase VFG1008 Protein 2e-69 42