Gene Information

Name : Elen_3068 (Elen_3068)
Accession : YP_003183400.1
Strain : Eggerthella lenta DSM 2243
Genome accession: NC_013204
Putative virulence/resistance : Virulence
Product : ATP-dependent chaperone ClpB
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 3566660 - 3569323 bp
Length : 2664 bp
Strand : -
Note : KEGG: sat:SYN_02525 ClpB protein; TIGRFAM: ATP-dependent chaperone ClpB; PFAM: ATPase AAA-2 domain protein; AAA ATPase central domain protein; ATPase associated with various cellular activities AAA_5; Clp domain protein; SMART: AAA ATPase

DNA sequence :
ATGAACATGGGTAACCTGAACAAGCTAGCCCTGACCGCTCAGGAAGCGCTGCAACAGACGATTGTCATCGCTTCCGAGAA
CGAGTCATCGCAGGCAGAGCCCATTCACATGTTGAAGGCTCTGCTGGAATCGAAAGAGAACAACCTGTCCGCTATCATCA
AGCGCATCGGTGCCGAGCCGTTCCAGCTGCAGGCCAACGTGGATGCCGAGATCCAGCGCATGCCGAAGGTCAGCGGGAAC
CCCGGCATGATGAGCGGCGTGCCTGGCCCGGCCCTGATGAACCTCATCGACAACGCCGTCAAGATCGCCGAGAAGCTGGG
CGACAGCTACGCCACCAGCGAGCATCTGCTGATCGCGCTGTCCGAGGAGAAGGGCGCCGCGGGCAAGATCCTCACTACGG
CCGGCGTCACGCGCAAGAGCATCGAGGCTGCCTACGAGGAGCTGCGCGGCGACACGCGCGTCACCGACCAGCAGAACAAA
GTGCAGTTCGAGGCGCTGGAGCAGTACGGCCAGAACCTCACGCAGAAGGCGCGCGAAGGCAAGCTCGACCCGGTCATCGG
CCGCGCCGAGGAGATCCGCCGCACCATCCAGGTGCTGTCGCGCCGCACGAAGAACAACCCCGTGCTCATCGGCGAGCCGG
GCACCGGCAAGACGGCCATCGTCGAGGGCCTGGCTCAGCGCATCGTGGCCGGCGACGTGCCCTCTTCGCTGAAGGACCGC
GACCTCGTGGCGCTCGACCTGGGCGCGATGGTGGCCGGCGCGAAGTATCGCGGCGAGTTCGAGGACCGCTTGAAGGCCGT
GCTGCGCGAGGTGAAGCAGAGCGAAGGACGCATCATCCTGTTCATCGACGAGCTGCACACCATCGTGGGCGCCGGCTCCA
CGGGCGACAGCTCCATGGACGCGGGCAACATGCTGAAGCCCGCGCTGGCCCGCGGCGAGCTGCATGCCATCGGCGCCACC
ACGCTGGACGAGTACCGCAAGTACATCGAGAAGGACGCCGCGCTCGAGCGCCGCTTCCAGCCCGTGCTGGTCACCGAGCC
CACGGTGGAGGACACCATCGCCATCCTGCGCGGTTTGAAGGAGAAGTACGAGATCCACCACGGCGTGCGCATCACCGACG
CCGCCATCGTGGCGGCGGCCGAGCTGTCGAACCGCTACATCTCCGACCGCTTCCTTCCCGACAAGGCCATCGACCTCATG
GACGAGGCCGCCAGCCGCCTGCGCATCGAGATCGACTCGATGCCCGAGGAGGTGGACGCCGCCGAGCGCAAGCTCACCCA
GATGCAGATCGAGGAGCAGGCGCTCATGAAGGAGAGCGACCAGGCCTCGCAAGAGCGCCTGGAAGCGCTGCGCCGCGAGA
TCGCCACGGCTCAGGAGGACCTCGACAAGCGCAAGGCCGAGTGGCAGAACGAGAAGGACGCCATCGAGCACGTGCAGAAC
CTCAAGAGCGACCTCGAGGGCGCGCAGCTTGAAGAGGAGCGCGCCACCCGCGAGGGCGACCTGGTGAAGGCCTCCGAGAT
CCGCTACGCGCGCATTCCCGCGCTGCAGCAGCAGCTGCATGCGGCCGAGGAAGAGCTGAACGTGAAGCAGCAGGACGGCG
CCATCCTCAAGGAGGAGGTGTCGGACGACGAGATCGCCGAGGTCGTTTCCACGTGGACGGGCATTCCCGTGCAGAAGATG
ATGCAGGGCGAGATGGCCAAGCTGGTCGACCTGGAGGACAAGCTGCACGAGCGCGTGGTGGGCCAGGACGAGGCCGTGTC
CTCGGTGGCCGGCGCCATCCGCCGCAACCGCGCCGGGTTGTCCGACCCGAACCGTCCCATCGGCTCGTTTTTGTTCCTGG
GACCCACGGGCGTGGGCAAGACCGAGCTGGCGAAGGCGCTGGCCGAGTACCTGTTCGACAGCGAGAAGGCCATGGTGCGC
ATCGACATGTCCGAGTACATGGAGAAGTTCTCGGTGCAGCGCCTGATCGGCGCGCCTCCGGGGTACGTGGGTTATGACGA
GGGCGGCCAGCTGACCGAGGCCGTGCGCCGCAAGCCTTATTCGGTGATCCTGCTCGACGAGATCGAGAAGGCGCACCCGG
ACGTGTTCAACATCCTGTTGCAGGTGCTGGACGACGGCCGCCTGACCGACGGCCAGGGCCGCGTGGTGTCGTTCAAGAAC
GCCATCATCATCATGACGTCGAACGTGGGATCGCAGTTCATCCGCGAGTTCGCCGAGCACGGCGACGAGAAGGCTATGAA
GCAGGCCATCGACGGCGCCCTGCGCGCGACGTTCCGCCCCGAGTTCATCAACCGCATCGATGACGTGGTGGTGTTCAACG
CGCTGAACATGACGAACATCGAGCCTATCGTCGATTTGCAGCTGGAAGAAGTGCGCGACCGTCTGGCCGACCGCCGCATC
ACGCTCGACGTGACGCCGGCGGCGATGGAGCACCTGTCCATCGACGGCTACGATCCCATCTTCGGAGCGCGTCCGTTGAA
GCGCCTCATCCAAAAGGAGATCGTCGACCGCATCGCCCAGAAGGTGGTGGAAGGCAAGCTGCGCGATCGCAGCCATGTGC
TGATCAGCATCGACCAGGACGGCAACTACGAATGCACCGTGGAAGAGCCCCTGGAGCTGGACGCCATGCCCCTCGACGAC
CTGCTGACCGAAGGCGATAAGTAA

Protein sequence :
MNMGNLNKLALTAQEALQQTIVIASENESSQAEPIHMLKALLESKENNLSAIIKRIGAEPFQLQANVDAEIQRMPKVSGN
PGMMSGVPGPALMNLIDNAVKIAEKLGDSYATSEHLLIALSEEKGAAGKILTTAGVTRKSIEAAYEELRGDTRVTDQQNK
VQFEALEQYGQNLTQKAREGKLDPVIGRAEEIRRTIQVLSRRTKNNPVLIGEPGTGKTAIVEGLAQRIVAGDVPSSLKDR
DLVALDLGAMVAGAKYRGEFEDRLKAVLREVKQSEGRIILFIDELHTIVGAGSTGDSSMDAGNMLKPALARGELHAIGAT
TLDEYRKYIEKDAALERRFQPVLVTEPTVEDTIAILRGLKEKYEIHHGVRITDAAIVAAAELSNRYISDRFLPDKAIDLM
DEAASRLRIEIDSMPEEVDAAERKLTQMQIEEQALMKESDQASQERLEALRREIATAQEDLDKRKAEWQNEKDAIEHVQN
LKSDLEGAQLEEERATREGDLVKASEIRYARIPALQQQLHAAEEELNVKQQDGAILKEEVSDDEIAEVVSTWTGIPVQKM
MQGEMAKLVDLEDKLHERVVGQDEAVSSVAGAIRRNRAGLSDPNRPIGSFLFLGPTGVGKTELAKALAEYLFDSEKAMVR
IDMSEYMEKFSVQRLIGAPPGYVGYDEGGQLTEAVRRKPYSVILLDEIEKAHPDVFNILLQVLDDGRLTDGQGRVVSFKN
AIIIMTSNVGSQFIREFAEHGDEKAMKQAIDGALRATFRPEFINRIDDVVVFNALNMTNIEPIVDLQLEEVRDRLADRRI
TLDVTPAAMEHLSIDGYDPIFGARPLKRLIQKEIVDRIAQKVVEGKLRDRSHVLISIDQDGNYECTVEEPLELDAMPLDD
LLTEGDK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 1e-113 42
aec27 YP_851418.1 ATPase Not tested PAI II APEC-O1 Protein 5e-110 42
aec27 AAQ96721.1 Aec27 Not tested AGI-1 Protein 4e-110 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Elen_3068 YP_003183400.1 ATP-dependent chaperone ClpB VFG0079 Protein 2e-164 47
Elen_3068 YP_003183400.1 ATP-dependent chaperone ClpB VFG2076 Protein 1e-120 43