Gene Information

Name : Elen_1917 (Elen_1917)
Accession : YP_003182270.1
Strain : Eggerthella lenta DSM 2243
Genome accession: NC_013204
Putative virulence/resistance : Virulence
Product : nucleotide sugar dehydrogenase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0677
EC number : -
Position : 2249012 - 2250328 bp
Length : 1317 bp
Strand : -
Note : TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP- glucose/GDP-mannose dehydrogenase dimerisation; UDP- glucose/GDP-mannose dehydrogenase; KEGG: ftn:FTN_1426 UDP-glucose/GDP-mannose dehydrogenase

DNA sequence :
GTGAGCGTGTACCAAGATTTGGTCGAGCGGAAGACGAAGCTATCCCTTATCGGACTGGGATATGTTGGCATGCCGATAGC
GGTTGAGTTCGCTAAGCATATCGAAGTTGTCGGATTCGATGTCAACGAAGAGAAAATCCGCTTGTACCGAAAGGGGGTCG
ATCCGACGAAAGAAGTAGGCGACGAGGCGATCAGCTCCACAGGCGTCGACTTCACGTCGAATCCCGAACGTTTACGGGAA
GCGCGTTTTCATATAGTTGCTGTTCCTACTCCGATCAATCAGGACAAGACCCCCGATCTGTCGCCGGTTGTTGGGGCGTC
GACCATGCTTGGCCGTCACCTTGAATGGGGTTCGATCGTGGTTTTCGAATCTACCGTCTATCCTGGGGTCACGGAGGACG
TATGCGTTCCTATCCTTGAGAGGGAATCCGGATTGCGGTGCGGCGTTGATTTCAAAGTGGGTTACAGTCCTGAGCGAATC
AACCCCGGGGACAAAGTCCATACCTTGACCACTATCCGAAAAATCGTTTCGGGCATGGATGATGAGTCCCTTGAAGAAAT
CAAACGCGTGTACGACATCGTGATAGAGGCAGGCACCTATCCGGTCTCCTCGATCAAAACAGCTGAAGCAATTAAGGTAG
TGGAGAACTCCCAGCGCGATATCAATATTGCCTTCATGAACGAGCTTGCCATGGTCTTCGACCGCATGGGTATCGATACG
AGCGAAGTCGTGGAGGGCATGAACACGAAGTGGAATGCGCTCGGCTTTAAACCAGGACTGGTTGGTGGGCATTGCATCGG
CGTTGATCCGTATTACTTTACCTACGAGGCCGAGAAGCTCGGTTACCACTCTCAGATCATTCTTTCGGGCAGAAGAGTGA
ACGATGCCATGGGAGGGTTTGTTGCCGAGACGGCCATCAGGGAGATGGTGCGAGTTGGGCTTGCTCCCAAGTCCTCGAAC
GTGGTCGTCTTGGGCATTACCTTCAAAGAGAACTGTCCCGATGTTCGAAATTCCAAGGTGTACGACATTGTCATGAGGCT
AAAGGAATATGGAGTCGAGCCGTCGGTGGTGGATCCTTGGGCTTCGGGAGACGAGGTGAAGCAGGTTTACGGCATGCAGC
TACGCGAGTCGGGTGATATTGCGAACGCAGATTGCCTGATTGTCGCGGTTGCCCATGATGAGTTCAAAGAGCTGGGCTTC
GAGCGTATTGATGCTTTCTTCGGAGACAAGCCCGACGAAAGCAAGGTGCTTTTGGATGTTAAAGGAATATTGGACGCGAA
GCGCTTCTCGTCTTATGGAAGCTTTTGGCGGCTATGA

Protein sequence :
MSVYQDLVERKTKLSLIGLGYVGMPIAVEFAKHIEVVGFDVNEEKIRLYRKGVDPTKEVGDEAISSTGVDFTSNPERLRE
ARFHIVAVPTPINQDKTPDLSPVVGASTMLGRHLEWGSIVVFESTVYPGVTEDVCVPILERESGLRCGVDFKVGYSPERI
NPGDKVHTLTTIRKIVSGMDDESLEEIKRVYDIVIEAGTYPVSSIKTAEAIKVVENSQRDINIAFMNELAMVFDRMGIDT
SEVVEGMNTKWNALGFKPGLVGGHCIGVDPYYFTYEAEKLGYHSQIILSGRRVNDAMGGFVAETAIREMVRVGLAPKSSN
VVVLGITFKENCPDVRNSKVYDIVMRLKEYGVEPSVVDPWASGDEVKQVYGMQLRESGDIANADCLIVAVAHDEFKELGF
ERIDAFFGDKPDESKVLLDVKGILDAKRFSSYGSFWRL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tviB NP_807945.1 VI polysaccharide biosynthesis UDP-glucose/GDP-mannose dehydrogenase Virulence SPI-7 Protein 1e-97 51
tviB NP_458740.1 Vi polysaccharide biosynthesis protein, UDP-glucose/GDP-mannose dehydrogenase Virulence SPI-7 Protein 1e-97 51
cap1L AAA64651.1 type 1 capsule synthesis gene Virulence SCCcap1 Protein 7e-103 49

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Elen_1917 YP_003182270.1 nucleotide sugar dehydrogenase VFG0431 Protein 5e-98 51