Gene Information

Name : Elen_1468 (Elen_1468)
Accession : YP_003181826.1
Strain : Eggerthella lenta DSM 2243
Genome accession: NC_013204
Putative virulence/resistance : Unknown
Product : bifunctional HTH-domain containing protein/aminotransferase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0436
EC number : -
Position : 1755641 - 1757245 bp
Length : 1605 bp
Strand : +
Note : in Corynebacterium glutamicum the aminotransferase can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor; this protein contains a helix-turn-helix domain at the N-terminus

DNA sequence :
ATGACCGAGAAGCAGGAAACGTTCGCCGAGCGTCTGGCCCGCGCGATGGCAGCCAAAGGCTACAAGCAGGCCGATCTCAT
CCGCATCGCGGGAGATCGCGGCATGAAGCTTGGGAAAAGCCAGGTCAGCCAATATGCGAACGGCAAAACGGTGCCCCGCA
GGCCCGTGGGGGAGGTGCTGGCCGACGTGCTGGGCGTGCCCGCCGCATGGCTGATGGAGGGCGCGGGGGAAATTGAACCT
GAAACCGTGTCCCGCGGCACCGCGGACGGCGTGAGCAGGCCGGCAAGCGCATCGCAGGGCGCAGGGGGAGCGGCCCCCGC
AGCCGGGGCGCACGCGGACGCCTCCGCGACGCCGATCATCGACCGTACCGAACCGAGGAGCGATACCATGCGCGAGATCA
AGAAGTCGACCAAGCTGGACAACGTACTGTACGACGTGCGCGGGCCGGTGGTGGAGGAAGCCGAGCGCATGGAGGAGGCC
GGCGCGCGCATCCTGAAGCTCAACATCGGCAACCCGGCGCCGTTCGACTTCCGCGCGCCTGAGGAGATGGTGTTCGACAT
GAGCCGCCAGCTGGCCGAATGCGAGGGCTACTCGTCGGCGAAGGGCCTGTTCTCGGCGCGCAAGGCCATCATGCAGTACG
CGCAGCTCAAGCACATTCAGGGCGTGGACATCGATGACGTGTACACCGGCAACGGCGTGAGCGAGCTCATCAATCTCAGC
ATGCTGGCGCTGCTGGACAACGGCGACGAGGTGCTGGTTCCTTCGCCCGACTACCCGCTGTGGACGGCGTGCGTCACGCT
TGCCGGCGGCACGCCGCTGCATTACGTGTGCGACGAGCAGGCGGAATGGTATCCCGATATGGACGACATCCGCAAGAAGA
TCACGAGCCGCACGAAGGCCCTCGTCATCATCAACCCGAACAACCCCACCGGCTCGCTCTACCCGCGCGAGGTGCTGCAG
GAGCTCGTCGACATCGCGCGCGAGCACGACCTCATCATCTTCTCGGACGAGATCTACGACCGCATCGTCATGGACGGTTT
GGAGCATATCTCCATCGCCTCGATGGCGCCCGACGTGTTCTGCGTCACGTTCAGCGGCCTGTCGAAGTCGCACATGGTGG
CGGGGTACCGCATCGGCTGGATGGTGCTTTCGGGAGACAAGGCGCGGGCGCGCGACTACATCCTGGGCGTCAACATGCTG
TGCAACATGCGCATGTGCTCGAACGTCCCCGCGCAGTCCATCGTGCAGACGGCTCTCGGCGGACACCAGAGCGTGCAGAG
CTACATCGTGCCGGGCGGGCGCGTGTACGAGCAGCGCGAGTACGTGTACAACGCGCTGAACGACATCCCCGGCGTGACCG
CGGTGAAGCCCAAGGCGGGCTTTTACATCTTCCCGAAGCTCGACGTGAAGAAGTTCAACATCACGGACGACGAGAAGTTC
GCGCTCGACCTGCTGCACGAGAAGCGCCTGCTCGTGGTGCACGGCGGCGGCTTCAACTGGAAGAAGCCCGACCACTTCCG
CGTGGTGTACCTGCCGCGCATCGAGGTGCTGGGCGACGCCATGCGCGACCTGGGCGACTTCTTGAGCCGCTACCGGCAAG
CGTGA

Protein sequence :
MTEKQETFAERLARAMAAKGYKQADLIRIAGDRGMKLGKSQVSQYANGKTVPRRPVGEVLADVLGVPAAWLMEGAGEIEP
ETVSRGTADGVSRPASASQGAGGAAPAAGAHADASATPIIDRTEPRSDTMREIKKSTKLDNVLYDVRGPVVEEAERMEEA
GARILKLNIGNPAPFDFRAPEEMVFDMSRQLAECEGYSSAKGLFSARKAIMQYAQLKHIQGVDIDDVYTGNGVSELINLS
MLALLDNGDEVLVPSPDYPLWTACVTLAGGTPLHYVCDEQAEWYPDMDDIRKKITSRTKALVIINPNNPTGSLYPREVLQ
ELVDIAREHDLIIFSDEIYDRIVMDGLEHISIASMAPDVFCVTFSGLSKSHMVAGYRIGWMVLSGDKARARDYILGVNML
CNMRMCSNVPAQSIVQTALGGHQSVQSYIVPGGRVYEQREYVYNALNDIPGVTAVKPKAGFYIFPKLDVKKFNITDDEKF
ALDLLHEKRLLVVHGGGFNWKKPDHFRVVYLPRIEVLGDAMRDLGDFLSRYRQA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
aspC YP_005682179.1 Aminotransferase AlaT Not tested PiCp 7 Protein 2e-110 55
aspC YP_005684271.1 Aminotransferase AlaT Not tested PiCp 7 Protein 2e-110 55
aspC YP_003784329.1 aspartate aminotransferase Not tested PiCp 7 Protein 2e-110 55
aspC YP_005686363.1 Aminotransferase AlaT Not tested PiCp 7 Protein 2e-110 55