Gene Information

Name : Apar_1040 (Apar_1040)
Accession : YP_003180059.1
Strain : Atopobium parvulum DSM 20469
Genome accession: NC_013203
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 1174502 - 1175944 bp
Length : 1443 bp
Strand : +
Note : KEGG: bcy:Bcer98_3282 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta

DNA sequence : 
ATGGCTCGCAAAAAGACCAAAATTGTTTGTACTATGGGTCCTGCAACAGAAAGTGATGAGGTTCTTCGTGAACTCATCCT
TGCTGGCATGAACGTCGCACGTTTCAACTTCTCGCACGGTAGCCATGAGTATCACCGCACTATGATTGGTCGCGTTCGTT
CTATCTCTGATGAACTTGGTATTCCTATTGCTATCATGCTCGATACAAAAGGTCCTGAGGTTCGCACCGGTCTTCTCGAG
GATGGCAAAAAGGTCACTCTTACCACCGGTGAGTCCGTCATTGTTACCACTGATGATGACGTCATCGGCAACGCTCAGCG
TTTCTCACTTGACTACAAGAATCTTCCAAAAGAGGTTAAGAAGGGCTCTATCATCCTTATTGATGATGGCCTTATTGGTC
TTGAAGTTGATCACGTTGAGGGCACTGATATGCACTGCAAGATTATCAACGGCGGTGAGCTTGGAGAGAAGAAGGGTGTA
AACGTTCCTAACGTTAATATCGGTCTTCCTTCCGTTACTGAGCAAGACCGCGCAGACATCATGTTTGGCTGCGAGCTTGG
TATTGACGCAATTGCTGCTTCCTTCATCCGCGATGGCGCTGCAGTTGAAGAGATTCGTAACATCTGCCGTGAAATGGGCA
CTCCTAACGTACAGATCTTCCCTAAGATTGAGTCTGCTCTTGGCGTAAAGAACTTTGACGAGATTCTTGCAGCTTCTAAC
GGCATCATGGTTGCCCGCGGTGACCTTGGTGTTGAGGTTCCTGCAGCTGAGGTTCCTCACATCCAGAAAACCATCATCAA
GAAGTGCAACGATGCTTACAAGCCTGTCATCACCGCAACTCAGATGCTTGACTCCATGATTCGCAATCCTCGTCCAACCC
GTGCAGAGGTTACAGACGTTGCTAACGCAATTTATGATGGTACTGACTGCGTCATGCTTTCTGGTGAGTCTGCAGCTGGT
AAATATCCTGTTGAAGCAGTTAAGACTATGGCTTCCATCTGCAAGGAAACCGAGAAATACCTGCCAGTCAAGGATGTCTA
TCACCAGCGTGAGGGCCTTAAGAACGTCAATGGTGCTACTGGTTTTGCTGCCGTTGATATGGCAATTCGCGTTGATGCTA
AGTGCATCATTTGCCCAACACACTCTGGCCGCACTGCTCGCCTTGTTTCTAACTTCCGTCCAAAGCGTCCTCTGTATGCA
ATGTCTCCATCCGATGAGGCAGTTCGTCGTACCTGCTTCTATTGGGGTGTCTATGCATTCAAGACCTCTGAGCAGGGCAC
ACTTTCTAACACCATGTACAACGCTTTGAACGTTGCAAAGGAAGTTGGCGTTGTAGAGACTGGCGATATTGTTGTTCTGA
CCGCTGGCGATCCTCATACCAGCCCACGTCTTGGTGACTACACCACTTCAACTAATGTTGCTATGATTTGCCAGGTTCAG
TAA

Protein sequence : 
MARKKTKIVCTMGPATESDEVLRELILAGMNVARFNFSHGSHEYHRTMIGRVRSISDELGIPIAIMLDTKGPEVRTGLLE
DGKKVTLTTGESVIVTTDDDVIGNAQRFSLDYKNLPKEVKKGSIILIDDGLIGLEVDHVEGTDMHCKIINGGELGEKKGV
NVPNVNIGLPSVTEQDRADIMFGCELGIDAIAASFIRDGAAVEEIRNICREMGTPNVQIFPKIESALGVKNFDEILAASN
GIMVARGDLGVEVPAAEVPHIQKTIIKKCNDAYKPVITATQMLDSMIRNPRPTRAEVTDVANAIYDGTDCVMLSGESAAG
KYPVEAVKTMASICKETEKYLPVKDVYHQREGLKNVNGATGFAAVDMAIRVDAKCIICPTHSGRTARLVSNFRPKRPLYA
MSPSDEAVRRTCFYWGVYAFKTSEQGTLSNTMYNALNVAKEVGVVETGDIVVLTAGDPHTSPRLGDYTTSTNVAMICQVQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 7e-87 48
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 3e-87 48
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 3e-87 48
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 5e-86 48

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Apar_1040 YP_003180059.1 pyruvate kinase VFG0479 Protein 1e-87 48