Gene Information

Name : Apar_0100 (Apar_0100)
Accession : YP_003179127.1
Strain : Atopobium parvulum DSM 20469
Genome accession: NC_013203
Putative virulence/resistance : Virulence
Product : ATP-dependent chaperone ClpB
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 108428 - 111010 bp
Length : 2583 bp
Strand : +
Note : KEGG: ank:AnaeK_0413 ATP-dependent chaperone ClpB; TIGRFAM: ATP-dependent chaperone ClpB; PFAM: ATPase AAA-2 domain protein; AAA ATPase central domain protein; Torsin; ATPase associated with various cellular activities AAA_5; Clp domain protein; SMART: AA

DNA sequence :
ATGAGACTAGATAAATGGGCTGTAACCGCCCAGGAAGCACTGCAGGCAGCTCTTGGTATTGCTGGCGACGCAGAGGCTTC
TGAGGTTACACCAACGCACCTGCTCAAGGCGTTGTTGGACAGCAACGAGCGCAACCTGCGTTCTATTTTGGAGAAGATTG
GCGCAGATCCTGACAGCATTGCTACGCAGGTAGACCAGGCAATCTCCAAGGCTCCAAAGGTAAGTGGAGCACAGATTGGC
ATTGGCAACGACCTTCTCAAGGTTATTAACGAGGCCGAGAAGCTTGCCACCAAGCTGGGAGATTCTTACGTTACCTCTGA
GCATTTGCTCACAGCGTTAGCAAACGATAACACTGACGCAGGTAGGATTCTTCGCGACGCCGGCATTACAGCCAAGCGTG
TAGAAGAGGTGTACAACGATCTTCGCGGTGATGAGCGTGTAACCTCGCAGGATGCAAAGCCACAGTTTGAGGCGTTGGAG
CAGTATGGTCGCAATGTGACCGATCTTGCTCGTCAGGGAAAGCTTGATCCAGTTATTGGCCGCGTCGAAGAAATTCGTCG
CACCATTCAGGTTCTGAGCCGCCGCACCAAGAACAATCCTGTTCTCATTGGCGAGCCTGGTGTTGGTAAGACCGCAATCG
TGGAAGGCCTGGCAGAACGCATTGTTTCTGGCGACGTTCCAAGTACCCTGCGCGATAAAGAGCTTGTTGAGCTTGACATG
TCTGCCCTGGTAGCGGGTGCAAAGTACCGTGGTGAGTTTGAGGACCGCCTGAAGAGCGTGGTAAAAGAGGTGGCCAAGTC
TAACGGCCAGATTATTCTCTTCATTGACGAGCTCCACACCATCGTAGGCGCTGGTGCTTCCGAGGGCTCCATGGACGCTG
GCAACATCTTGAAGCCAGCACTTGCCCGTGGAGAGCTCCGTGCAATTGGTGCCACTACGCTGGATGAATACCGCAAGTAC
ATCGAGAAGGACGCTGCTCTTGCACGTCGTTTCCAGACCGTACTTGTCTCTGAGCCTACTGTTGAAGATACCATTTCTAT
CTTGCGTGGCCTTAAGGAGAAGTACGAGCAGCACCACCGCGTCCGTATTACGGACTCCGCTTTGGTTGCAGCAGCAGACC
TTTCTAACCGCTACATTTCTGACCGATTCTTGCCAGATAAGGCGATTGACTTGGTAGATGAGGCAGCGTCAAGACTTCGC
ATGGAGCTTGATTCTATGCCAGCAGAGATTGATGCGGTTGATCGTCAGCTTACTCAGATGCAGATTGAGGAGCAGGCTCT
GATGAAGGAGGAGGACGCTGCTTCCAAGGAGCGCCTGGAGAACCTTCGCGCAGAGATTGCTACGACGCAGGAGAAGCTGG
ATGGCATGAAGGCCAACTGGCAGAACGAGCGCGGCGCAATTGACCTGGTACAGGACTTGAAATCCCAGATTGAGGAAGCA
AAGACGCAGATGGAGCGTGTGACTCGCGAGGGTAATTTAGCGCAGGCATCTGAGCTTCGTTACAGCACTATTCCAGAGCT
TGAACGTAAATACGATGAGGCAGAAAAGGCCCTTCTCGCCAAGCAGGAAGACGGCGGAATCCTCAAGGAAGAGGTCACCA
CGGACGAGATTGCCGAGGTAGTTTCTTCGTGGACCGGCGTGCCTGTGTCCAAGATGATGCAGGGCGAGATGGACAAGCTC
AAGAACCTTGAGGACCAGCTTCACCTGCGCGTTATTGGTCAGGACGATGCTGTTTCCGCAGTTGCTGCAGCGGTCCGTCG
TTCTCGCGCGGGTCTGGCAGATCCAAACAAGCCTCTGGGCAGCTTCTTCTTCCTGGGCCCAACCGGTGTGGGCAAGACCG
AGCTGGCAAAGGCGCTGGCAGAGCTGCTGTTTGACGACGAGCGCTCGCTGATCCGCATTGATATGTCTGAGTACATGGAG
AAGTTCTCGGTCCAGCGACTCATTGGCGCACCTCCAGGATACGTGGGTTATGACGAGGGTGGCCAGCTCACCGAGGCAGT
TCGTAGGCATCCATACTCCGTCATCTTGCTGGACGAGATGGAGAAGGCCCATCCTGATGTCTTCAACATCTTGCTGCAGG
TACTGGACGATGGTCGACTAACGGACGGTCAAGGTAGGGTAGTCAGCTTCAAGAACACCATCATTATCATGACCAGTAAT
GTTGGTTCGCAGTTCATTGCCGGTGCTGGCGAAGAGGGTCTTACTGAAGAGTCCAGAAAGCAAGTTATGGAGGCGCTACG
TAGCTCCTTCCGCCCTGAGTTCTTGAACCGTATCGACGACGTGGTTGTCTTCCAGCCTTTGGGTCTTGAAGATATTGAGC
GCATCGTTGATATTCAGCTCAAGGATGTTCGTAGTAGACTTGCTAACGAGCGCATGACGCTGGAGCTTTCTGAGGCTGCA
AAGCAGTCACTGGCTCTTGATGGTCTGGATCCTGTTTATGGTGCTCGTCCTTTGAAGCGACTGATTCAGCGTCGCGTTGT
TGACCAGGTAGCAAACTTGATTATTGCAGGTGAGCTGTCTGAGGGCGATACTGTTCTGATTGATACTGACGAGAACGGCA
ATTTGGTTGCTCGTAAGAAGTAA

Protein sequence :
MRLDKWAVTAQEALQAALGIAGDAEASEVTPTHLLKALLDSNERNLRSILEKIGADPDSIATQVDQAISKAPKVSGAQIG
IGNDLLKVINEAEKLATKLGDSYVTSEHLLTALANDNTDAGRILRDAGITAKRVEEVYNDLRGDERVTSQDAKPQFEALE
QYGRNVTDLARQGKLDPVIGRVEEIRRTIQVLSRRTKNNPVLIGEPGVGKTAIVEGLAERIVSGDVPSTLRDKELVELDM
SALVAGAKYRGEFEDRLKSVVKEVAKSNGQIILFIDELHTIVGAGASEGSMDAGNILKPALARGELRAIGATTLDEYRKY
IEKDAALARRFQTVLVSEPTVEDTISILRGLKEKYEQHHRVRITDSALVAAADLSNRYISDRFLPDKAIDLVDEAASRLR
MELDSMPAEIDAVDRQLTQMQIEEQALMKEEDAASKERLENLRAEIATTQEKLDGMKANWQNERGAIDLVQDLKSQIEEA
KTQMERVTREGNLAQASELRYSTIPELERKYDEAEKALLAKQEDGGILKEEVTTDEIAEVVSSWTGVPVSKMMQGEMDKL
KNLEDQLHLRVIGQDDAVSAVAAAVRRSRAGLADPNKPLGSFFFLGPTGVGKTELAKALAELLFDDERSLIRIDMSEYME
KFSVQRLIGAPPGYVGYDEGGQLTEAVRRHPYSVILLDEMEKAHPDVFNILLQVLDDGRLTDGQGRVVSFKNTIIIMTSN
VGSQFIAGAGEEGLTEESRKQVMEALRSSFRPEFLNRIDDVVVFQPLGLEDIERIVDIQLKDVRSRLANERMTLELSEAA
KQSLALDGLDPVYGARPLKRLIQRRVVDQVANLIIAGELSEGDTVLIDTDENGNLVARKK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 2e-107 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Apar_0100 YP_003179127.1 ATP-dependent chaperone ClpB VFG2076 Protein 6e-117 45
Apar_0100 YP_003179127.1 ATP-dependent chaperone ClpB VFG0079 Protein 2e-138 43
Apar_0100 YP_003179127.1 ATP-dependent chaperone ClpB VFG2084 Protein 6e-110 43