Gene Information

Name : Hmuk_0744 (Hmuk_0744)
Accession : YP_003176582.1
Strain : Halomicrobium mukohataei DSM 12286
Genome accession: NC_013202
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 710604 - 711989 bp
Length : 1386 bp
Strand : +
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGTTGAGCAGACAGTTCGTCCGTGAGAACGCCGAGATGGTCCGAGAGGCCATCGAGCAGAAGGGCGTCACGGGCGTCGA
CCTCGACGAGATCCTGCGGATCGACGCGGAGTGGCGCGAGCTGAAGGCGGAGGGCGACGACCTGCGCCACCAGCGCAACG
AGGTCTCCAGCGAGATCGGCGAGTACAAGCGCGAGGGCGAGGAGGAGAAGGCCCAGGACGCCATCGAGCGCTCGAGCGAG
CTGAAAGCGGAGCTCCAGCGCGTCGAGGACCGCGCCGACGAACTCGAAGCGAAGCTGGAGGCGCGCCTGCTGGAGATCCC
CAACGTCCCTCACGAGTCGGTGCCGGTCGGCGAGGGCGAGGACGACAACGTCGAGCGCTACCGCGAGGGGTTCGACGACC
TGCGGACCCTGCCCGAGGACGTGGTCCCTCACTACGAGCTGGGCGAGCGACTCGACATTCTGGACTTCGAGCGCGGCGCG
AAGGTTTCGGGCGGCGGCTTCCAGTTCGTCAAGGGCGAGGGCGCACGGCTGGAGTACGCGCTGATCCAGTTCATGCTCGA
CGTACACCGCGAGCAGGAGTACATCGACGTGTTCCCGCCGCTGCCGGTCAACAGCGAGTCGATGCGTGGGACCGGCCAGC
TGCCGAAGTTCGCCGAGGACGCCTACCGCATCGAAGCCCGACAGGACGACGAGTACGACGACGACGACCTGTGGCTGCTC
CCGACCGCGGAGGTGCCGGTGACCAACATGTACCGCGATGAGATCCTGCTGGACGACGACCTCCCGATCAAACACCAGGC
GTTCTCGCCGAACTTCCGGCGCGAGGCCGGCGAACACGGGACCGAGACCCGCGGGTACGTCCGCGTCCACCAGTTCAACA
AGGTCGAACTCGTGAACTTCGTCCGGCCGGAGAACAGCTACGAGCGTCTCGAAGGACTGCTCTCCGAGGCCGAGGAAGTG
CTCGACCGCCTGGACCTGCCCTACCGCGTGCTGGACATGTGTACCGGCGACATGGGGTTCACCCAGGCCAAGAAGTACGA
CATCGAGGTGTGGGCACCCGGCGACGACATGGACGACGGCCCCGAGGAGGGCGGGCGCTGGCTGGAGGTGTCCTCGATCT
CGAACTTCGAGGACTTTCAGGCCCGGCGCGCGGGCATCCACTACCGGCCCGAGCGCCACGAATCGGCGGAGTACCTCCAC
ACGCTCAACGGCAGCGGCGTCGCCGTCCCGCGGGTGATGGTCGCAATCATGGAGTACTACCAGAACGACGACGGCACGAT
CACCGTCCCCGAACCGCTCCGGCCGTACATGGGCGGTCAGGAAGTCATCGAAGGCCACGAGCCCGTCGGGGAGAGCGCCG
TCGGCGAAGGCGACGGCGACGACTGA

Protein sequence :
MLSRQFVRENAEMVREAIEQKGVTGVDLDEILRIDAEWRELKAEGDDLRHQRNEVSSEIGEYKREGEEEKAQDAIERSSE
LKAELQRVEDRADELEAKLEARLLEIPNVPHESVPVGEGEDDNVERYREGFDDLRTLPEDVVPHYELGERLDILDFERGA
KVSGGGFQFVKGEGARLEYALIQFMLDVHREQEYIDVFPPLPVNSESMRGTGQLPKFAEDAYRIEARQDDEYDDDDLWLL
PTAEVPVTNMYRDEILLDDDLPIKHQAFSPNFRREAGEHGTETRGYVRVHQFNKVELVNFVRPENSYERLEGLLSEAEEV
LDRLDLPYRVLDMCTGDMGFTQAKKYDIEVWAPGDDMDDGPEEGGRWLEVSSISNFEDFQARRAGIHYRPERHESAEYLH
TLNGSGVAVPRVMVAIMEYYQNDDGTITVPEPLRPYMGGQEVIEGHEPVGESAVGEGDGDD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 7e-78 49