Gene Information

Name : Hmuk_3233 (Hmuk_3233)
Accession : YP_003175693.1
Strain :
Genome accession: NC_013201
Putative virulence/resistance : Resistance
Product : ATPase P
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG2217
EC number : -
Position : 21507 - 23864 bp
Length : 2358 bp
Strand : +
Note : TIGRFAM: ATPase P; ATPase, P-type (transporting), HAD superfamily, subfamily IC; cadmium-translocating P-type ATPase; PFAM: E1-E2 ATPase-associated domain protein; Heavy metal transport/detoxification protein; Haloacid dehalogenase domain protein hydrolas

DNA sequence :
ATGACGAGCAAATCGGAGACGGCGGGAGAGGGTGGACAGGACCCCGGTGAGACGACCGTCCGGGTGACCGTCCCCGAGAT
GGACTGTCCGTCGTGTGCACAGAAAGTCGACAAGAGCCTCCAGCGCGTCGACGGCGTGCGTGAGACGACTCTCCAGCCGA
CGACCGGAACGGCGATCATGACCATCGATACGGGCGAGACGAGCGAGGCCGAAGTCCGCGGAGCCATCGAGAGCGCCGGC
TACGAGGTCAGCGGAGAGCCGGGCGACTCGTCCGGCGAGGGGATCGAGGTCGCTCCTCCGGCGGAGATCTGGCGGAGTTC
GCGGGCCGTCAAGACGTGGATCGGAGCTGCGTTCGTGACGCTCGGACTCCTCTTCGAGTTCGTCCTCGGGGGCCAGAACG
TCGCTCTCGGGAGCGTCTTCGAGCTCTCGCTTCATCTCGCCGACGGACTGTTCCTCGTCGCGATCGTCGTCAGTGGCTAC
CCGGTCGTCCGCGGAGGCTACTACTCGGCGAAAAACAGGAGCCTCGACATCGACCTCCTGATGGGGACGGCGATCATCGC
CGCGACGGGGATCGGGTACTTCGTGGAGGCCGCGACGCTCGCGGTCCTGTTCAGCATCGCAGAGCTCCTCGAAGACTACG
CGATGGACCGAGCGCGGGACTCGCTGCGTGAACTGATGGAACTGTCCCCCGACGAAGCGACAGTCCGTCGGAACGGAGAC
GAGGAGACCGTGCCCGCCGAGGACGTGGCCGTCGGCGAGACGGTCGTCGTCCGCCCGGGCGAGAAGATTCCACTCGACGG
CACGATCGTCGAGGGCACCAGCGCGGTCGACGAATCGCCGATCACCGGCGAGAGCGTCCCGGTCGACAAGAACGTCGGCG
ACGAGGTGTACGCCGGCAGCATCAACGCGGAGGGGTACTTCGAGTTCGAGGCCACGTCGTCGGCCTCGGAGTCGACGCTC
TCCCAGATCATCGAGATGGTCCAGGGCGCACAGGAAAAGAAGACCGAGAAAGAGCAGTTCGTCGACCGCTTTGCCGGCTA
CTACACGCCGACGGTCGTCGTGCTGGCGATACTGACGGCCGCGCTCCCGCCGCTGTTCATCGGTGGCGGCGCGACCGTCA
GTGTCGCCGGGATCGGCCACACGTTCGTCGGGAGCTGGCAGACATGGTTCGTCCGCGGGCTGACGCTGCTGGTCATCGCG
TGCCCGTGCGCGTTCGTCATCTCGACGCCCGTCTCGGTCGTCTCGGGCATCACGAGCGCCGCCAAGAACGGCGTCCTCAT
CAAGGGCGGCAACCACCTCGAAGCGATGGGCGGCGTCGACGCCGTCGCGCTGGACAAGACCGGGACGCTCACGAAAGGCG
AGCTCGCCGTCACCGACGTGGTTCCCCTCGGCGAGGCGAGCGAGACGGAGCTGCTCCGGTACGCCGCCGCCCTCGAACAG
CGCAGCGAGCACCCCATCGCCGAGGCGATCCGCGAGCGCGCCCGAGAATCGGCGGTCGGCGAGCTGCCCGTCGTCGAGGC
GTTCGAGAGCATCACCGGAAAGGGGCTCCGCGCGGAGAGCGACGGCGAGACGTACTACGCCGGCAAGCCCGCGCTGTTCG
AGGAACTGGGCTTCGATCTGTCACACGCCCACGCCCGTCCCGACGGCGGTACCGTCGTCGAGGCGACCGACGACGAGTGT
GACCGGGACGACTGTGCCGACCTCGAAGCCGGCGCGATATCGCAGTTCGAAGCGGAGGGGAAGACGGTCGTCCTCGTCGG
CACGGCCACCGAACTGCTCGGCGTCGTCGCCATCGCCGACGAGGTTCGCCCGGCAGCGTCACGAGCGATCGAGCGGCTAC
ACGAACTCGGCGTCGAACACGTCGTGATGCTCACCGGCGACAACGAGGGGACCGCCCGCGCGATCGCCGACCGCGTCGGG
GTCGACGAGTACCGCGCCGAACTGCTGCCCGACGAGAAGGTCGACGCCGTCGAGTCGTTACAGGCCAGCCACGGCGACGT
GGCCATGGTCGGTGACGGGATCAACGACGCGCCCGCGCTGGCGACCGCCGACGTCGCGGTCGCGATGGGAGCCGCGGGAA
CCGATACCGCCCTCGAAACGGCCGACATCGCGCTGATGGGCGACGACATCGGGAAGCTTCCGTACCTGTATGCGCTGTCT
AACGAAGCAAACAGCGTCATCCGACAGAACATCTGGGCGAGTCTGGGCGTGAAGGCGGTGCTGGCACTCGGTGTGCCCCT
GGGACTGGTCAGCGTCGCGCTGGCGGTCGTCGTCGGCGACATGGGAATGAGCCTCGGGGTCACCGGAAACGCCATGCGAC
TGTCCCGAGTCACACCGGATCGCTTCTTCGAGGAGTGA

Protein sequence :
MTSKSETAGEGGQDPGETTVRVTVPEMDCPSCAQKVDKSLQRVDGVRETTLQPTTGTAIMTIDTGETSEAEVRGAIESAG
YEVSGEPGDSSGEGIEVAPPAEIWRSSRAVKTWIGAAFVTLGLLFEFVLGGQNVALGSVFELSLHLADGLFLVAIVVSGY
PVVRGGYYSAKNRSLDIDLLMGTAIIAATGIGYFVEAATLAVLFSIAELLEDYAMDRARDSLRELMELSPDEATVRRNGD
EETVPAEDVAVGETVVVRPGEKIPLDGTIVEGTSAVDESPITGESVPVDKNVGDEVYAGSINAEGYFEFEATSSASESTL
SQIIEMVQGAQEKKTEKEQFVDRFAGYYTPTVVVLAILTAALPPLFIGGGATVSVAGIGHTFVGSWQTWFVRGLTLLVIA
CPCAFVISTPVSVVSGITSAAKNGVLIKGGNHLEAMGGVDAVALDKTGTLTKGELAVTDVVPLGEASETELLRYAAALEQ
RSEHPIAEAIRERARESAVGELPVVEAFESITGKGLRAESDGETYYAGKPALFEELGFDLSHAHARPDGGTVVEATDDEC
DRDDCADLEAGAISQFEAEGKTVVLVGTATELLGVVAIADEVRPAASRAIERLHELGVEHVVMLTGDNEGTARAIADRVG
VDEYRAELLPDEKVDAVESLQASHGDVAMVGDGINDAPALATADVAVAMGAAGTDTALETADIALMGDDIGKLPYLYALS
NEANSVIRQNIWASLGVKAVLALGVPLGLVSVALAVVVGDMGMSLGVTGNAMRLSRVTPDRFFEE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed BAB47609.1 cadmium resistance protein B Not tested Type-III SCCmec Protein 1e-113 41
cadA BAC57487.1 Probable cadmium-transporting ATPase (Cadmium efflux ATPase) Not tested Type-IIIinv SCCmec Protein 1e-113 41
SE0075 NP_763630.1 cadmium resistance protein B Not tested SCCpbp4 Protein 2e-109 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Hmuk_3233 YP_003175693.1 ATPase P BAC0298 Protein 1e-80 44