Gene Information

Name : secA (LC705_00948)
Accession : YP_003173638.1
Strain : Lactobacillus rhamnosus Lc 705
Genome accession: NC_013199
Putative virulence/resistance : Unknown
Product : preprotein translocase subunit SecA
Function : -
COG functional category : U : Intracellular trafficking, secretion and vesicular transport
COG ID : COG0653
EC number : -
Position : 937554 - 939917 bp
Length : 2364 bp
Strand : +
Note : functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis ap

DNA sequence :
ATGGCCAATATTCTTAGAAAATGGGTCGAAAGCGATAAGCGAGAAATCGGTCGCCTCGGCAAAATCGCTGATCAAGTTCA
GCGCTATGAAGATGAATATGCAGCATTATCAGATGATCAATTAAAAGCAAATACCCAAAAATTCAAGGATCGCCTTGCAG
CAGGGGCAACGTTAGACGATATTTTACCGGAAGCTTTTGCCACCGCGCGTGAAGGGGCTAAACGAGTTTTAGGGTTATTC
CCGTTTCGGGTTCAAATTATTGGCGGGATCGTTTTACATGAAGGCAATATTGCGGAAATGAAAACCGGTGAAGGTAAAAC
TTTGACGGCAACCATGCCCGTTTATTTGAATGCCTTGACTGGTAAAGGTGTCCACGTGGTTACCGTTAACGAGTACTTGT
CCACGCGTGATGCAACGGAAATGGGCGAGTTGTACAATTGGCTCGGTCTCAGCGTCGGGTTGAATCTTAACTCCAAGAAC
AGTGACGAAAAACGCGAAGCCTATAATTGCGATATCACTTATTCCACCAATAGTGAACTCGGCTTTGACTATTTGCGAGA
CAACATGGTGGTTTATAAGGAACAGATGGTACAACGGCCACTGAATTTTGCAATTGTTGATGAAGTTGATTCGATTCTCA
TTGATGAGGCCCGGACGCCTTTGATTATTTCCGGTGGCGCAGAAAAGACAACCGGCCTTTATATTCGGGCGGACCGCTTC
GTTAAGACGCTTAAAGCCGATACTGATTACAAGATTGACTGGCCAACGAAGACCATTTCGCTCACTGAAAGCGGCATTCG
CAAAGCCGAAAAGAATTTTGGCTTGGATAACCTATACGATACCGAAAATACGGCTTTAACCCACCATATCGACCAAGCAT
TGCGGGCAAATTACATTATGCTTAAAGATATCGACTATATGGTGTCTAACGGCGAAGTGCTGATTGTCGATCAATTTACC
GGTCGGGCAATGGAAGGCCGGCGCTATTCCGATGGCTTGCATCAGGCAATTGAAGCCAAAGAAGGGGTACAAATCCAGGA
TGAAAATAAGACGATGGCTAACATCACTTATCAAAACTTCTTCCGGATGTACACCAAGCTGGCAGGGATGACTGGGACCG
CTAAAACGGAGCAAGAAGAGTTCCGCGAAATCTATAATATGGAAGTTATTTCGGTTCCAACCAATAAACCGGTTATCCGG
GTTGACTCACCGGATGTTTTGTACCCGACTTTGGATGCTAAATTCAATGCGGTTGTTGACGATATCAAAAAACGCCATAA
AAAAGGACAGCCGATTCTGGTTGGGACGGTTGCGATTGAGTCGAGTGAACGCCTGAGTAAGCAATTAGATGATGAAAAGA
TCCCGCACACGGTTTTGAATGCGAAGAACCACTTTAAAGAAGCGGAAATCATCATGAATGCCGGGCAACGAGGCGCCGTG
ACAATTGCGACCAACATGGCTGGTCGTGGGACGGATATTAAATTAGGCCCTGGTGTCACCGAGTTAGGCGGTTTGGCTGT
TATTGGGACTGAGCGGCATGAGAGTCGCCGAATTGATAATCAATTACGTGGCCGTTCCGGTCGTCAAGGTGATCCGGGTT
CTACCCAATTTTACCTGAGTCTAGAAGATGACTTGATGAAACGGTTTGGCTCTGAGCGGATTAAAGCAATGCTGGATCGG
TTCAAGGTTGCCGATGACGATCAGGTCATTCAAAGTCGAATGATCTCACGGCAGGTTGAATCAGCGCAGAAGCGTGTCGA
AGGGAATAACTACGACACACGTAAAAACACGCTGCAGTATGATGATGTGATGCGTGAACAGCGTGAAGTCATCTATAAGC
AGCGTCAGCAGATTATCAATGAAGACGAGACCCTCAAGCCCGTTTTGATGGCGATGATTAATCGAACCATCACCCGCATC
GTTCAAACGCATACCCAAGGCGATCAAAAGGATTGGAATCTTGATGCGTTGTATGCTTGGATCACCGCAAACATGGCCGA
TCCGGAGAAATTCAAGCGCAGCGAACTTGATGGCAAGTCGCAAGATGAGCTCATCGGTTTACTGGCGGATATGGCTGAAA
ATAACTTCCAGCATAAAAACAAGCAACTTGGCGATGACGCGCAGATGCTAGAATTCGAAAAAGTGGTCATCTTACGCGTT
GTTGACTCAGCTTGGACGGATCACATTGACGCCATGGATCAACTACGCCAGTCTATTGGTTTGCGTGGTTATGGGCAGAT
GAATCCGCTAGTCGAATATCAAGAAGAAGGCTACCGGATGTTTGAGGAAATGATTGCGTCAATTGATGATGATGTGACCC
GACTGTTCATGAAAGCCGAAATTCGGCAAAATATTCGCCGTTAA

Protein sequence :
MANILRKWVESDKREIGRLGKIADQVQRYEDEYAALSDDQLKANTQKFKDRLAAGATLDDILPEAFATAREGAKRVLGLF
PFRVQIIGGIVLHEGNIAEMKTGEGKTLTATMPVYLNALTGKGVHVVTVNEYLSTRDATEMGELYNWLGLSVGLNLNSKN
SDEKREAYNCDITYSTNSELGFDYLRDNMVVYKEQMVQRPLNFAIVDEVDSILIDEARTPLIISGGAEKTTGLYIRADRF
VKTLKADTDYKIDWPTKTISLTESGIRKAEKNFGLDNLYDTENTALTHHIDQALRANYIMLKDIDYMVSNGEVLIVDQFT
GRAMEGRRYSDGLHQAIEAKEGVQIQDENKTMANITYQNFFRMYTKLAGMTGTAKTEQEEFREIYNMEVISVPTNKPVIR
VDSPDVLYPTLDAKFNAVVDDIKKRHKKGQPILVGTVAIESSERLSKQLDDEKIPHTVLNAKNHFKEAEIIMNAGQRGAV
TIATNMAGRGTDIKLGPGVTELGGLAVIGTERHESRRIDNQLRGRSGRQGDPGSTQFYLSLEDDLMKRFGSERIKAMLDR
FKVADDDQVIQSRMISRQVESAQKRVEGNNYDTRKNTLQYDDVMREQREVIYKQRQQIINEDETLKPVLMAMINRTITRI
VQTHTQGDQKDWNLDALYAWITANMADPEKFKRSELDGKSQDELIGLLADMAENNFQHKNKQLGDDAQMLEFEKVVILRV
VDSAWTDHIDAMDQLRQSIGLRGYGQMNPLVEYQEEGYRMFEEMIASIDDDVTRLFMKAEIRQNIRR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
secA2 YP_006310687.1 preprotein translocase subunit SecA2 Not tested FWisland_3 Protein 3e-148 42