Gene Information

Name : clpC (LC705_02503)
Accession : YP_003175193.1
Strain : Lactobacillus rhamnosus Lc 705
Genome accession: NC_013199
Putative virulence/resistance : Virulence
Product : ATP-dependent Clp protease ATP-binding subunit
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 2540749 - 2543256 bp
Length : 2508 bp
Strand : -
Note : -

DNA sequence :
ATGGACAACTTATTTACCCCTAGTGCTAAAAATGTGTTGCTTTTAGCCCAGGAACAAGCGAAGTACTTCCATCATCATGC
TGTTGGCACGGAACACTTGCTTATGGCTTTGGTTATGGAAAAGGATGGTATCGCTGGTAAGACGCTGCGTCAGTTAGGGG
TCACAGAAAATGATGTCCATGACGAGATCGAGCGCTTCACAGGATATGGAACTGTTGATGCCGCCAGTCAAGCTAGCGAT
AGTTATTTGCCATACTCACCAAAAGGCAAGGAAATTCTGGCATTTGCCGGGGACGAAGCAAAACGCTTAGGGGCGTTAAA
AATCGGCACCGAGCATATTCTGCTGGGACTATTGCGAGAAGACGATATTTTAGCTGCGCGGATTTTACAAAACTTAGGGC
TCAGTCTCTCGAAGACGCGTCAGATGGTCTTCAAGAAAATGGGCATTGCGGATACGGCGGCAAAGCGGCGGCCAATGGCA
CGTGGCGGCGCTCGCCAAGACGGTCAGGGGACACCAACGCTTGATGGCCTCGCCCGTGATCTAACCCAGATGGCGCGCGA
AAATCGGATGGATCCGGTGGTTGGTCGCGACAAAGAAGTTCGGCGCTTGATTCAAATCTTGGCTCGGCGCACTAAGAACA
ACCCGGTCTTGATTGGTGAACCCGGTGTCGGCAAAACGGCCATTGCAGAAGGCTTCGCTGAAAAAATTGTGGCTGGAAAA
GTGCCGGATGATATGCTGAACAAACGCTTGATGATGCTTGACATGGGTTCGTTGGTTGCAGGCACTAAGTATCGTGGTGA
GTTTGAAGATCGGCTGAAGAAAATTATTGATGAGATTTATAAAGATGGCAATGTCATTTTATTCATCGATGAATTGCACA
CATTGATCGGTGCTGGCGGTGCTGAAGGGGCAATTGACGCTTCAAATATCCTGAAACCGGCATTGGCACGTGGCGAGCTT
CAGCTAATCGGCGCCACGACTTTAGATGAATATCAAAAGTACATTGAAAAAGATGCGGCCTTGGAGCGGCGGTTTGCAAC
AATTCAAGTTGACGAACCGACTGAGGAAGAAGCCGAACAGATTCTGAAAGGTTTGCGTCCGCGTTACGAAGCACACCATG
GCGTTACGATTACCGATGAAGCGCTGCATGAAGCGGTTGTGTTGTCGTCACGTTACATTACAACGCGTTTTCTTCCGGAT
AAGGCTATTGACTTGGTCGATGAAAGTGCGGCTAAAGTTCGCCTTGATAAAGCTAACGTGGAGACCAAAGCTGATAAACT
TCAGGATGAATTAGCTAAACTGGTTGCCGACAAAGAAGATGCAATTGATCATCAAGACTTCGAAACGGCTGCTACAATCC
GGACTAAAGAAGCGGGCGTCAAGGCTAAACTTGCCGATACGCCTGAACCGGTGAATGAAAGTGGTGTTCGTACCGATATC
AAGGTCACGGGCGCAGACGTTGCCGAAGTTGTATCGCAATGGACCGGCGTGCCGGTCACGCAACTGCAGAAAAAGGAATC
TGAACGGTTGGTTAATCTCGAGAAGATTCTGCATCAGCGAGTTGTTGGCCAGGATGAAGCCGTTTCAGCAGTTGCACGGG
CAATTCGGCGTGCTCGTTCCGGGTTGAAGGATCCGACCAGACCGATTGGCTCCTTCATGTTCTTGGGACCAACCGGCGTC
GGCAAAACCGAATTAGCTAAAGCGTTGGCAGAAGCGATGTTTGGTTCCGAGGACGCCATGATTCGGGTCGATATGTCCGA
GTATATGGAGAAATTCAGTACGAGCCGGTTAATCGGCGCAGCGCCAGGCTATGTCGGTTATGACGAAGGCGGTCAATTGA
CGGAAAAGGTTCGCAACAAGCCATATTCGGTCGTTTTACTCGATGAAGTTGAAAAGGCGCATCCTGATGTCTTCAACATT
TTGTTACAAGTCTTGGATGATGGCTATTTAACCGATGCTAAGGGTCGGCGGGTCGATTTTCGGAATACCATTTTGATTAT
GACCAGCAATATCGGAGCAACTGCCATTCGCGATGATAAGACAGTTGGATTTGGTGCAAAAGATCCAACAGCCGACTTCA
ATGCCATGAAGAGTCGGATGTTGGCTGAACTGAAAAAGAGCTTCCGTCCAGAATTTCTTAATCGAATTGACGAAACTGTT
GTCTTCCATAGCTTGAACAAGGCTGAGTTGCATGAGATCGTCAAGATTATGACCAAAACCGTGCTTAGTCGTATCAAAGA
TCAAGGAATTGACGTTAAAATTACGCCAGCCGGGATTGATGCGATTGCCGCGGCTGGGTTTGATCCTGAATATGGTGCGC
GCCCGATCCGCCGTGCCTTGCAAACGGATGTTGAAGACCAACTCAGTGAGCTATTGCTGACGGGTCAGGCTAAAACCGGT
GATTTGATTCAAATCGGCGCTAAAAAAGGCAAGCTGACGTTTACAGTCAAGGAAAACAAAGGTAAGCATAAAGAAAACGG
CGCTTCTAAAGAACCTGTCAAGGCATGA

Protein sequence :
MDNLFTPSAKNVLLLAQEQAKYFHHHAVGTEHLLMALVMEKDGIAGKTLRQLGVTENDVHDEIERFTGYGTVDAASQASD
SYLPYSPKGKEILAFAGDEAKRLGALKIGTEHILLGLLREDDILAARILQNLGLSLSKTRQMVFKKMGIADTAAKRRPMA
RGGARQDGQGTPTLDGLARDLTQMARENRMDPVVGRDKEVRRLIQILARRTKNNPVLIGEPGVGKTAIAEGFAEKIVAGK
VPDDMLNKRLMMLDMGSLVAGTKYRGEFEDRLKKIIDEIYKDGNVILFIDELHTLIGAGGAEGAIDASNILKPALARGEL
QLIGATTLDEYQKYIEKDAALERRFATIQVDEPTEEEAEQILKGLRPRYEAHHGVTITDEALHEAVVLSSRYITTRFLPD
KAIDLVDESAAKVRLDKANVETKADKLQDELAKLVADKEDAIDHQDFETAATIRTKEAGVKAKLADTPEPVNESGVRTDI
KVTGADVAEVVSQWTGVPVTQLQKKESERLVNLEKILHQRVVGQDEAVSAVARAIRRARSGLKDPTRPIGSFMFLGPTGV
GKTELAKALAEAMFGSEDAMIRVDMSEYMEKFSTSRLIGAAPGYVGYDEGGQLTEKVRNKPYSVVLLDEVEKAHPDVFNI
LLQVLDDGYLTDAKGRRVDFRNTILIMTSNIGATAIRDDKTVGFGAKDPTADFNAMKSRMLAELKKSFRPEFLNRIDETV
VFHSLNKAELHEIVKIMTKTVLSRIKDQGIDVKITPAGIDAIAAAGFDPEYGARPIRRALQTDVEDQLSELLLTGQAKTG
DLIQIGAKKGKLTFTVKENKGKHKENGASKEPVKA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 50

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpC YP_003175193.1 ATP-dependent Clp protease ATP-binding subunit VFG0079 Protein 0.0 61
clpC YP_003175193.1 ATP-dependent Clp protease ATP-binding subunit VFG0080 Protein 1e-142 48