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Name : guaA (LC705_01959) Accession : YP_003174649.1 Strain : Lactobacillus rhamnosus Lc 705 Genome accession: NC_013199 Putative virulence/resistance : Unknown Product : GMP synthase Function : - COG functional category : F : Nucleotide transport and metabolism COG ID : COG0519 EC number : - Position : 1977815 - 1979368 bp Length : 1554 bp Strand : - Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway DNA sequence : GTGGCAAATGACCAGAACAAGGATTACGACAAGATCATCGTCCTCGATTATGGTAGTCAGTATAATCAGTTAATCACCCG GCGTATCCGGGAATTTGGTATCTACTCTGAATTAAAGCCTCATACCATCACAGCGGCTGAAGTCAAGGAAATCGCGCCTA AGGGAATTATCTTCTCTGGTGGTCCGAACAGTGTCTATGACGAAGGTGCGCTCGGGGTTGATGAGGACATTTTCAAACTT GGCATTCCGATTCTAGGCGTGTGTTATGGTATGCAGCTGATGGCTCAACGACTCGGTGGTGATGTCGAACCGGCAGACAA CCGCGAATACGGCAAGGCCGACATCGAAGTCACCGATGCCAGCGCCAAACTCTTCCACGATCTGCCAAAAGACCAGACTG TCTGGATGAGTCACGGCGATTTAGTCACCCGCGTTCCGGATGGCTTCCGCACCACGGCCACCAGCGTCAACTGCCCAATC AGTGCGATGGACGACGATGACCGTAAATTCTACGGCATTCAGTTCCACGCCGAAGTGCAAAACACTCAATACGGCCACGA AATTCTGCACCATTTTGCCTTCGACGTCTGCCACGCCGAAGCCAACTGGAGCATGGACGACTTCATCACCAAACAAATCG CCAAAATCCGGGCCGAAGTCGGTGACAAGCGCGTCCTTCTTGGCCTCTCCGGCGGGGTTGACTCTTCCGTTGTCGGCGTT TTGCTACACAAAGCAATCGGCACCCAGCTAACCAGCATCTTCGTTGATCACGGCCTGCTGCGAAAAGGCGAAGCAGAACA AGTCATGGACAGCCTCAAAGGTAAATTTGGCCTCAACATCATCAAAGTTAACGCCAAAGACCGCTTCCTCAATGACCTAA AAGGCGTCACTGACCCAGAAAAGAAACGGAAAATCATCGGCCGCGACTTCATTGAGGTATTCAACGAAGAAGCTGCCAAA CTCAACGGCATCGAATTCCTCGCCCAAGGTACGCTATACACCGATGTGGTTGAATCCGGAACCGATACCGCGCAAACAAT CAAGTCCCACCATAACGTCGGCGGCCTACCAGAAGACCTCAAATTCAAACTAATCGAACCACTAAACAAACTCTTCAAAG ATGAAGTCCGCGAACTCGGCGAAAAACTGGGTATGCCACATTCACTCGTCTGGCGCCAACCATTCCCAGGCCCAGGCCTC GGCATCCGGGTTATCGGTGAGGTGACTGAAGATAAACTGGAGATCGTGCGCGACTCCGACTATATTTTACGGGAAGAAAT CGCTAAGCACGGGTTGGATAAGGATATTTGGCAATATTTTACGGTGTTGCCAGGCTTCCGTTCCGTGGGTGTAATGGGCG ACGGTCGCACCTACGACTACACCATCGGCATCCGCGCCATTACCTCAATCGACGGCATGACCGCCGACTTTGCCCGGATT GACTGGGATGTATTACAGGAGATCTCGAGTCGGATTGTTAATGAAGTGAAGCACGTTAATCGCGTTGTGTATGATATTAC TTCTAAGCCACCGGCAACGATTGAGTGGGAATAG Protein sequence : MANDQNKDYDKIIVLDYGSQYNQLITRRIREFGIYSELKPHTITAAEVKEIAPKGIIFSGGPNSVYDEGALGVDEDIFKL GIPILGVCYGMQLMAQRLGGDVEPADNREYGKADIEVTDASAKLFHDLPKDQTVWMSHGDLVTRVPDGFRTTATSVNCPI SAMDDDDRKFYGIQFHAEVQNTQYGHEILHHFAFDVCHAEANWSMDDFITKQIAKIRAEVGDKRVLLGLSGGVDSSVVGV LLHKAIGTQLTSIFVDHGLLRKGEAEQVMDSLKGKFGLNIIKVNAKDRFLNDLKGVTDPEKKRKIIGRDFIEVFNEEAAK LNGIEFLAQGTLYTDVVESGTDTAQTIKSHHNVGGLPEDLKFKLIEPLNKLFKDEVRELGEKLGMPHSLVWRQPFPGPGL GIRVIGEVTEDKLEIVRDSDYILREEIAKHGLDKDIWQYFTVLPGFRSVGVMGDGRTYDYTIGIRAITSIDGMTADFARI DWDVLQEISSRIVNEVKHVNRVVYDITSKPPATIEWE |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| SAMSHR1132_03620 | YP_005324884.1 | GMP synthase | Not tested | vSa¥á | Protein | 7e-170 | 67 |
| guaA | YP_001331415.1 | GMP synthase | Not tested | vSa¥á | Protein | 1e-169 | 67 |
| SAPIG0468 | YP_005733278.1 | GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) | Not tested | SAPI-S0385 | Protein | 8e-170 | 67 |
| guaA | NP_938969.1 | GMP synthase | Not tested | Not named | Protein | 3e-124 | 49 |
