Gene Information

Name : serS (LC705_01877)
Accession : YP_003174567.1
Strain : Lactobacillus rhamnosus Lc 705
Genome accession: NC_013199
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : -
Position : 1897641 - 1898924 bp
Length : 1284 bp
Strand : -
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGTTAGATCTCAAGTTGATTCGGCAAAAGCCGGAGTGGGCAAAAAAGAAGTTGGCTGCTCGCGCGATCAAGGGTGAGGA
AATCGATGAATTAATCGCCCTTGATGAGAAACGACGTAAGGTAACAGTTCAAACCGAGGAGTTAAAGGCAAAGCGTAATG
AAGTTTCCGGCCAGATCGCGGTGATGAAACGGAACAAAGAAAACGCTGACGAGCAAATCGCGGCTATGCGTGAAGTTGGT
CAAAAAATCAGCCAGTTAGATAAAGAATTAGCAGAACTGAATGAAAAAGTCACCTATATTCTGGTTCGGTTACCTAACTT
TCCGGCTGATGATGTCCCGATGTCACTAAATGAAGACGACTCGCGTGAAGAATATAAATGGGGCAACATTCCTCATTTCG
ATTTTCAACCGAAACATCACTGGGATATCGGCGAGAAACTAGGTATTTTGGACTTTGAACGGGCGGCCAAAGTATCAGGT
AGCCGCTTTGTCTACTATAAAGGTGCAGGTGCGCGACTAGAGCGAGCCGTTTATAACTTCTTCTTGGATGAACACCAAAA
AGAAGGCTATGAAGAAATTATTCCACCATATTTGGTTAACAACGATTCAATGTTTGGCACGGGTCAATTTCCTAAGTTTA
CTGATGCAACGTACACCATCACAAACGATGGGGAGCCATTAACCATGATTCCAACCGCAGAAGTGCCGCTGGTCAATTAT
TATCGCGGGGATATTATGGATGCTGCCAAATTGCCGGTTAACTTCACCGCACTGACACCAGCCTTTCGTTCCGAAGCAGG
AAGCGCAGGCCGGGATACTCGTGGATTAATCCGGATGCATCAATTTAACAAGGTCGAAATGGTCAAGTTTTGCAAACCCG
AAGATTCCTGGAAAGAATTAAAAAACTTGATTCACGATGCAGAGGACCTGTTACGCAAGTTGGGCCTTCCGCATCACGTC
ATCACCTTAGCCAGCAACGATGCCAGCTTTACGAGTGCTAAAACAAACGATCTTGAAGTGTGGTTCCCGGCACAGGATCG
CTATCGTGAAATTTCGAGTTGCAGTAATTGCACGGATTTCCAGGCACGTCGAGCACAAATCCGTTATCGCGATGATGATG
GCAAGCTGCAATTTGTTCATACACTCAACGGCTCAGGCCTTGCAGTGGGACGGACCGTCGCTGCCATTCTTGAAAATTAT
CAGCAAGCCGATGGAACGGTTAAGATTCCTGACGTTCTGGTTCCCTACATGCACGGCCAAACTGCAATCAAGCAGGAAGA
TTAA

Protein sequence :
MLDLKLIRQKPEWAKKKLAARAIKGEEIDELIALDEKRRKVTVQTEELKAKRNEVSGQIAVMKRNKENADEQIAAMREVG
QKISQLDKELAELNEKVTYILVRLPNFPADDVPMSLNEDDSREEYKWGNIPHFDFQPKHHWDIGEKLGILDFERAAKVSG
SRFVYYKGAGARLERAVYNFFLDEHQKEGYEEIIPPYLVNNDSMFGTGQFPKFTDATYTITNDGEPLTMIPTAEVPLVNY
YRGDIMDAAKLPVNFTALTPAFRSEAGSAGRDTRGLIRMHQFNKVEMVKFCKPEDSWKELKNLIHDAEDLLRKLGLPHHV
ITLASNDASFTSAKTNDLEVWFPAQDRYREISSCSNCTDFQARRAQIRYRDDDGKLQFVHTLNGSGLAVGRTVAAILENY
QQADGTVKIPDVLVPYMHGQTAIKQED

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 1e-127 61