Gene Information

Name : nrdF (LC705_01492)
Accession : YP_003174182.1
Strain : Lactobacillus rhamnosus Lc 705
Genome accession: NC_013199
Putative virulence/resistance : Unknown
Product : ribonucleotide-diphosphate reductase subunit beta
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0208
EC number : -
Position : 1493285 - 1494265 bp
Length : 981 bp
Strand : +
Note : B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE

DNA sequence :
ATGGTAAAACAGTATATTGCGATTAACTGGAATGCAATTGAAGATGAAGTAGATAAAGCCACTTGGGAAAAATTAACCGA
ACAGTTTTGGCTCGACACCCGAATCCCCTTGTCCAACGATTTGGACGATTGGCGTTCATTGAGTCCGGATGAACAATGGG
TCGTTGGCCACGTTTTCGGCGGGTTGACTTTACTGGATACCCTGCAAAGTCAAGACGGTATGGCAAGTTTACGCCAAAAC
ATCCGGACCCAACAGGAAACCGCGGTGCTTAATAATATTCAGTTTATGGAAAGTGTCCATGCGAAGAGTTATTCATCAAT
TTTCTCGACGCTGAACACGCCTGCCGAGATCGATGAAATCTTTGACTGGACCAATCACAATGAGCATTTGCAGTACAAGG
CCAACAAAATCAATGACATCTATCACAACGGCTCGGCACTACAAAAGAAAATTGCCAGTGTTTTCCTGGAAACGTTCCTG
TTTTATTCAGGCTTCTTTACCCCGCTTTATTACCTGGGCAACAACAAGCTGACGAATGTGGCCGAAATTATCAAGCTGAT
TATTCGGGATGAGAGTGTTCACGGAACCTATATCGGCTATAAATTCCAGTTAGGCTTCAATGAATTACCGGAAGCAGAGC
AACAACAACTGCAGGATTGGATGTACGATCTGTTATACGACCTCTATGAAAACGAAGAAAAGTATACGAACGATCTCTAC
GCTAAAACCAAATGGACCGATGAAGTTTTGACTTTCCTGCGTTATAACGCCAATAAGGCCCTGATGAATCTGGGACAGGA
AACCGCCTTTCCGGATACCGCCGATGACGTTAATCCGATTGTAATGAACGGCATTTCAACATCAACGGCTAACCATGATT
TCTTCTCACAGGTCGGTAATGGTTACCGGCTCGGTCAGGTCGAAGCAATGGAAGATGATGATTATTCATTCTCGACTGAA
GATAAAGGGCACAAGGATTAA

Protein sequence :
MVKQYIAINWNAIEDEVDKATWEKLTEQFWLDTRIPLSNDLDDWRSLSPDEQWVVGHVFGGLTLLDTLQSQDGMASLRQN
IRTQQETAVLNNIQFMESVHAKSYSSIFSTLNTPAEIDEIFDWTNHNEHLQYKANKINDIYHNGSALQKKIASVFLETFL
FYSGFFTPLYYLGNNKLTNVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEAEQQQLQDWMYDLLYDLYENEEKYTNDLY
AKTKWTDEVLTFLRYNANKALMNLGQETAFPDTADDVNPIVMNGISTSTANHDFFSQVGNGYRLGQVEAMEDDDYSFSTE
DKGHKD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cur_1479 YP_001800873.1 ribonucleoside-diphosphate reductase subunit beta Not tested Not named Protein 7e-69 47