Gene Information

Name : nrdE (LC705_01491)
Accession : YP_003174181.1
Strain : Lactobacillus rhamnosus Lc 705
Genome accession: NC_013199
Putative virulence/resistance : Unknown
Product : ribonucleotide-diphosphate reductase subunit alpha
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0209
EC number : -
Position : 1491062 - 1493233 bp
Length : 2172 bp
Strand : +
Note : Catalyzes the rate-limiting step in dNTP synthesis

DNA sequence :
ATGTCACTAAAAACCATTAGTCCGGATGAGGTTACTTATTACGCACTTAACAACGAGATTAACATTCCCGTTAACGACCA
AATTCCGCTTAACAAAGATAAAGAAGCATTGCAGGCCTTTTTGACCGAAAATGTTGCACCCAATACCATGAAATTTGCTT
CATTACAGGAGCGCTTAAAGTATCTGGTTGAACATCACTATTATGAAGCAGACTTTTTAAAGAAATATCAACCGGCCTTT
TTGGAGAAGTTGAATCAGTTTCTCACCGCGCAGCATTTCCAATTTAAGTCGTTCATGGCTGCGTATAAATATTATGCTCA
GTACGCGTTAAAAACCGATGACGGGACGCAATATCTTGAAGATTACAAAGATCGCGTTTTCGCTAATGCCCTTTTCTTTG
CGGATGGTAACGAAGATTTGGCCGTTGACTTAGCCGATGAGATGATTCATCAGCGCTATCAACCGGCTACCCCATCCTTC
CTGAATGCAGGTCGGGCGCGGCGTGGTGAACTGGTCTCTTGTTTCCTGCTGCAAATCACCGATGACATGAATTCAATTGG
TCGGGCAATCAACTCGGCTTTGGAACTTTCCCGTATCGGCGGCGGTGTCGGCTTGACGCTGTCGAACCTGCGTGAAGCCG
GTGCACCGATCAAGGGCATTGACGGTGCTGCCAGTGGTGTCTTGCCAGTCATGAAGTTGCTGGAAGATTCATTCTCCTAC
AGTAACCAGCTGGGTCAGCGCCAAGGTGCCGGGGTGGTTTATTTGAACGTCTTCCATCCGGATATCATCAGCTTCCTAGG
CGCTAAGAAGGAAAATGCCGATGAAAAGTATCGGGTGAAAACGTTGAGCCTTGGTGTGATTGTGCCAGACAAATACTACG
AACTCATCAAGGCTAACGCTGACATGTACCTCTTCTCCCCTTATTCAGTCGAACGCGCGTATGGCAAGCCATTTTCTTAC
GTGGATATCACGAAGGAATACGACAAGATGGTAGCCAATCCTGATATTAAGAAATACAAGATCAAAGCGCGCGACTTGGA
AAACGAGATCTCCAAGTTGCAGCAAGAATCCGGCTATCCGTACATCATTAATATCGATACGGCTAATCGCGCCAATCCGA
TCGAAGGTAGGATTATCATGAGTAACCTGTGCTCTGAAATTATGCAGGTGCAGGTTCCGTCTAAGCTCAATAATCGTCAG
GAGTACGAGGTCTTAGGGACAGATGTTTCTTGCAACTTGGGGAGTACGAATATTCCTAACTTGATGCACAGCCGTGATTT
TGGTCATAGCGTCGAAGCCATGGTACGCGCGCTCACCTATGTCACGGATCACAGCAACATTGACGTTGTGCCATCCGTGC
AGCATGGCAATCACCTTGCCCACAGTATTGGCCTTGGTGCGATGGGCCTGCACACCTATTTTGCCAAGAACCACATGTAC
TACGGTTCACCGGAAAGCCTTGATTTCACTAACATCTACTTCCTGCTGCTTAATTATTACACGCTCAAAGCTTCCAATAA
GATCGCTAAGGAACGCGGCGAATCCTTCCACAACTTTGAAAATAGCAAGTACGCAGATGGCAGTTATTTTGACAAGTATC
TCAATCAAACCTGGGCGCCGAAGTATGATAAGGTTCGCGACTTGTTCAAAAACATTCACATTCCAACGCAGGCTGACTGG
CAGGCACTCAAAGAAGATGTGATGAAAAACGGTTTGTACCATCAAAATCGGATGGCAGTTGCACCTAATGGCTCAATTAG
CTATATCAACGACACCAGCGCTTCATTACAGCCAATTGTCAACCGGATTGAGGATCGTCAGGAAAAGAAAATCGGTACCA
TTTATTATCCGGCACCAGGGCTTTCCAACGACACGATGCCTTACTATCAAAGCGCCTATGACATTGATATGCGCAAAGTC
ATTGATGTCTACGCAGCAGCCCAGCAACATGTTGACCAGGGGATGGCGATGACGTTGTTTATGCGTAGTACCATCCCAGC
TGGCCTTTATCCGTGGAAAGATGGTCGTACTGATAAAATGACCACCCGGGACTTGAATATCTTGCGGAATTACGCCCACT
ATAAAGGCATTAAGTCCATTTACTACATCCGGACTTATACCGATGACCAAGAAGAAATCGGCAGCAACGCTTGTGAAAGT
TGCTCAATTTGA

Protein sequence :
MSLKTISPDEVTYYALNNEINIPVNDQIPLNKDKEALQAFLTENVAPNTMKFASLQERLKYLVEHHYYEADFLKKYQPAF
LEKLNQFLTAQHFQFKSFMAAYKYYAQYALKTDDGTQYLEDYKDRVFANALFFADGNEDLAVDLADEMIHQRYQPATPSF
LNAGRARRGELVSCFLLQITDDMNSIGRAINSALELSRIGGGVGLTLSNLREAGAPIKGIDGAASGVLPVMKLLEDSFSY
SNQLGQRQGAGVVYLNVFHPDIISFLGAKKENADEKYRVKTLSLGVIVPDKYYELIKANADMYLFSPYSVERAYGKPFSY
VDITKEYDKMVANPDIKKYKIKARDLENEISKLQQESGYPYIINIDTANRANPIEGRIIMSNLCSEIMQVQVPSKLNNRQ
EYEVLGTDVSCNLGSTNIPNLMHSRDFGHSVEAMVRALTYVTDHSNIDVVPSVQHGNHLAHSIGLGAMGLHTYFAKNHMY
YGSPESLDFTNIYFLLLNYYTLKASNKIAKERGESFHNFENSKYADGSYFDKYLNQTWAPKYDKVRDLFKNIHIPTQADW
QALKEDVMKNGLYHQNRMAVAPNGSISYINDTSASLQPIVNRIEDRQEKKIGTIYYPAPGLSNDTMPYYQSAYDIDMRKV
IDVYAAAQQHVDQGMAMTLFMRSTIPAGLYPWKDGRTDKMTTRDLNILRNYAHYKGIKSIYYIRTYTDDQEEIGSNACES
CSI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cur_1481 YP_001800875.1 ribonucleotide-diphosphate reductase subunit alpha Not tested Not named Protein 7e-178 53