Gene Information

Name : secA (LGG_00899)
Accession : YP_003170645.1
Strain : Lactobacillus rhamnosus GG
Genome accession: NC_013198
Putative virulence/resistance : Unknown
Product : preprotein translocase subunit SecA
Function : -
COG functional category : U : Intracellular trafficking, secretion and vesicular transport
COG ID : COG0653
EC number : -
Position : 901376 - 903739 bp
Length : 2364 bp
Strand : +
Note : functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis ap

DNA sequence :
ATGGCCAATATTCTTAGAAAATGGGTCGAAAGCGATAAGCGAGAAATCGGTCGCCTCGGCAAAATCGCTGATCAAGTTCA
GCGCTATGAAGATGAATATGCAGCATTATCAGATGATCAATTAAAAGCAAACACCCAAAAATTCAAGGATCGCCTTGCAG
CAGGGGCAACGTTAGACGATATTTTACCGGAAGCTTTTGCCACCGCGCGTGAAGGGGCTAAACGAGTTTTGGGGTTATTC
CCGTTTCGGGTTCAAATTATCGGCGGGATCGTTTTACATGAAGGCAATATTGCGGAAATGAAAACCGGTGAAGGTAAAAC
TTTGACGGCAACCATGCCCGTTTATTTGAATGCCTTGACTGGTAAAGGGGTCCACGTGGTTACCGTTAACGAGTACTTGT
CCACGCGTGATGCAACGGAAATGGGCGAGTTGTACAACTGGCTCGGTCTCAGCGTCGGGTTGAATCTTAACTCCAAGAAC
AGTGACGAAAAACGCGAAGCCTATAACTGCGATATCACCTATTCCACCAATAGTGAACTCGGTTTTGACTATTTGCGAGA
CAACATGGTGGTTTATAAGGAACAGATGGTACAACGGCCACTGAATTTTGCAATTGTTGATGAGGTTGATTCGATTCTCA
TTGATGAGGCCCGGACACCTTTGATTATTTCCGGTGGCGCAGAAAAGACAACCGGCCTTTATATTCGGGCGGACCGCTTC
GTTAAGACGCTTAAAGCCGATACTGATTACAAGATTGACTGGCCAACGAAGACCATTTCGCTCACTGAAAGCGGCATTCG
CAAAGCCGAAAAGAATTTTGGCTTGGATAACCTATACGATACCGAAAATACGGCTTTAACCCACCATATCGACCAAGCAT
TGCGGGCAAATTACATTATGCTTAAAGATATCGACTATATGGTGTCTAACGGCGAAGTGCTGATTGTCGATCAATTTACC
GGTCGGGCAATGGAAGGCCGGCGCTATTCCGATGGCCTGCATCAGGCAATTGAAGCCAAAGAAGGGGTCCAAATCCAGGA
TGAAAATAAGACGATGGCTAACATCACTTATCAAAACTTCTTCCGGATGTACACCAAGCTGGCAGGGATGACCGGAACCG
CTAAAACGGAGCAAGAAGAGTTCCGCGAAATCTATAATATGGAAGTTATTTCGGTTCCAACCAATAAACCGGTTATCCGG
GTTGATTCACCGGATGTTTTGTACCCGACTTTGGATGCTAAATTCAATGCGGTTGTTGACGATATCAAAAAACGTCATAA
AAAAGGGCAGCCGATTCTGGTTGGGACGGTTGCGATTGAGTCTAGCGAACGTTTGAGTAAGCAATTAGACGATGAAAAAA
TCCCGCACACGGTTTTGAATGCGAAGAACCACTTTAAAGAAGCGGAAATCATCATGAATGCCGGGCAACGAGGCGCTGTG
ACAATTGCGACCAACATGGCTGGTCGTGGGACGGATATTAAATTAGGCCCTGGTGTCACCGAGTTAGGCGGTTTGGCTGT
TATTGGGACCGAACGGCATGAGAGTCGCCGAATTGATAATCAATTACGTGGCCGTTCTGGTCGTCAAGGTGATCCGGGTT
CTACCCAATTTTACCTGAGTCTAGAAGATGACTTGATGAAACGGTTTGGCTCTGAGCGGATCAAAGCAATGCTGGATCGG
TTCAAGGTTGCCGATGACGATCAGGTCATTCAAAGTCGGATGATCTCACGGCAGGTTGAATCAGCGCAGAAGCGTGTCGA
AGGGAATAACTACGACACGCGTAAAAACACGTTGCAGTACGATGATGTGATGCGTGAACAGCGTGAAGTTATCTATAAGC
AGCGCCAGCAGATTATCAATGAAGACGAGACCCTGAAGCCCGTTTTGATGGCGATGATTAATCGAACCATCACCCGCATC
GTTCAAACGCATACCCAAGGCGATCAAAAGGATTGGAATCTTGATGCGTTGTATGCCTGGATCACCGCAAACATGGCCGA
TCCGGAGAAATTCAAGCGCAGCGAACTTGATGGCAAGTCGCAAGATGAGCTCATCGGTTTACTGGCGGATATGGCTGAAA
CTAACTTCCAGCATAAAAACAAGCAACTTGGCGATGACGCGCAGATGCTAGAATTCGAAAAAGTGGTCATCTTACGCGTT
GTTGACTCAGCTTGGACGGATCACATTGACGCCATGGATCAACTACGCCAGTCTATTGGTTTGCGTGGTTATGGGCAGAT
GAATCCGCTAGTCGAATATCAAGAAGAAGGCTACCGGATGTTTGAGGAAATGATTGCGTCAATTGATGATGATGTGACCC
GATTGTTCATGAAAGCCGAAATTCGGCAAAATATTCGCCGTTAA

Protein sequence :
MANILRKWVESDKREIGRLGKIADQVQRYEDEYAALSDDQLKANTQKFKDRLAAGATLDDILPEAFATAREGAKRVLGLF
PFRVQIIGGIVLHEGNIAEMKTGEGKTLTATMPVYLNALTGKGVHVVTVNEYLSTRDATEMGELYNWLGLSVGLNLNSKN
SDEKREAYNCDITYSTNSELGFDYLRDNMVVYKEQMVQRPLNFAIVDEVDSILIDEARTPLIISGGAEKTTGLYIRADRF
VKTLKADTDYKIDWPTKTISLTESGIRKAEKNFGLDNLYDTENTALTHHIDQALRANYIMLKDIDYMVSNGEVLIVDQFT
GRAMEGRRYSDGLHQAIEAKEGVQIQDENKTMANITYQNFFRMYTKLAGMTGTAKTEQEEFREIYNMEVISVPTNKPVIR
VDSPDVLYPTLDAKFNAVVDDIKKRHKKGQPILVGTVAIESSERLSKQLDDEKIPHTVLNAKNHFKEAEIIMNAGQRGAV
TIATNMAGRGTDIKLGPGVTELGGLAVIGTERHESRRIDNQLRGRSGRQGDPGSTQFYLSLEDDLMKRFGSERIKAMLDR
FKVADDDQVIQSRMISRQVESAQKRVEGNNYDTRKNTLQYDDVMREQREVIYKQRQQIINEDETLKPVLMAMINRTITRI
VQTHTQGDQKDWNLDALYAWITANMADPEKFKRSELDGKSQDELIGLLADMAETNFQHKNKQLGDDAQMLEFEKVVILRV
VDSAWTDHIDAMDQLRQSIGLRGYGQMNPLVEYQEEGYRMFEEMIASIDDDVTRLFMKAEIRQNIRR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
secA2 YP_006310687.1 preprotein translocase subunit SecA2 Not tested FWisland_3 Protein 2e-148 42