Gene Information

Name : leuS (LGG_00848)
Accession : YP_003170594.1
Strain : Lactobacillus rhamnosus GG
Genome accession: NC_013198
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : -
Position : 856708 - 859119 bp
Length : 2412 bp
Strand : +
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGGCATACGATCATCATGAGATCGATAAGAAGTGGCAGCGTTATTGGGCCGAACATAACGAATTCAATACCACGACCGA
TCCGAAGAAACCGAATTATTATGCATTAGACATGTTCCCATATCCATCAGGCCAGGGCTTGCATGTTGGACATCCAGAAG
GCTACACCGCAACCGATATTGTGGCGCGGATGAAACGAATGCAAGGATTTAACGTTTTGCATCCGATGGGGTGGGATGCA
TTCGGTTTACCAGCTGAGCAATATGCCTTGAATACCGGTCACAATCCCCGGACTTTTACTAAGCAAAACATTGAAACGTT
TAAGCGTCAAATTAATAGCCTTGGTTTTTCATATGATTGGAACCGGGAAATTAATACGACCGATCCGAATTACTACAAAT
GGACACAATGGATTTTTGAACAACTGTATAAACATGGACTAGCGTATGAAGCTGAAGTTCCGGTTAACTGGAGCCCTGAT
TTGGGAACCGTAGTCGCTAACGAAGAAGTGATCGATGGTAAAACGGAGCGGGGCGGTTTTCCGGTTGTTCGTAAGCCGAT
GCGGCAATGGATGCTAAAGATCACAGCGTACGCCGATAAATTACTTGCAGACTTGGATGATTTGGATTGGCCTGAATCAA
TCAAGCAGATGCAACGAAACTGGATCGGCAAGTCAACCGGGGCGCAAATCACGTTTACGGTCACCGATACCCAGGAAAAG
TTTGACGTTTTCACAACGCGTCCGGACACCCTTTTTGGCGCAACTTATGTCGTCATGGCACCAGAGCACGACTTGGTTGA
AAAGATTACGACGCCGGAACAGCAGGCAGTTGTTGATGCTTATATTGAAGAAGCAGCACATAAGTCCGATCTTGACCGGA
CGGCGCTCGATAAGGAAAAAACCGGCGTCTGGACGGGTGCTTATGCGACCAACCCCGTCAATGGCGAGAAGTTGCCGATC
TGGATTTCAGATTATGTACTGGCAACTTATGGTACCGGGGCAATTATGGCGGTGCCGGCCCACGATGATCGCGACTATGC
TTTTGCTAAGAAGTTTGGCATCGAAATCAAACCGGTCATTGAAGGTGGCAACATTGACGAGGCAGCTTATACCGGCGATG
GCGTGCACATTAATTCCGGCTTTCTTGATGGCTTAAACGAACAGGATGCCATTGATCGGATGATCGCATGGCTGGAAGAT
AAAGGCATTGGCCAGGCAAAAGTTAACTATAAGTTGCGTGACTGGGTCTTTTCCCGGCAACGTTATTGGGGCGAACCGAT
TCCAGTGATTCATTGGGAAGATGGCGAGACAACCCTGGTACCAGAAGATGAATTGCCGCTGACTTTGCCGGAAGAAGTTG
ATATCAAGCCAAGCGGAACCGGTGAGAGCCCGCTCGCCAATTTGACAGACTGGGTCAATGTTGTGGACAAGAATGGCCGT
AAAGGTAAGCGGGAGACGAACACCATGCCGCAATGGGCCGGTTCTTCGTGGTACTTCCTGCGCTTTGTCGATCCACATAA
CAAAGAGGCCTTGGCTGATTATGACAAGCTCAAGCAGTGGATGCCAGTGGACCTTTATATCGGCGGGGCCGAACATGCCG
TGCTGCATCTGCTGTACGCGCGTTTTTGGAATCTGTTCCTTTATGATATCGGTGCGATTCCAAACAAGGAACCATTCCAG
CGCCTGTTTAACCAAGGCATGATCTTGGGTGATAATCATGAAAAGATGAGTAAGTCTAAGGGGAATGTTGTTAACCCCGA
TGACGTGGTGGACGAATACGGTGCCGATACTTTGCGCCTGTATGAAATGTTCATGGGACCGTTGGATGCCGGTATCGCTT
GGTCCACAGATGGTTTGGCGGGTGCCCGCAAGTTCTTGGATCGGGTATGGAGTGCCTTTATTGATGATGAAGGTAAACTG
CGCGATCGTATCACCACCATTAATGACGGTCGTTTGGATAAGGTCTACAACGAAACGGTTAAAAAAGTAACCGAGGACTA
TGAGGCGTTGCATTTTAACACGGCGATTGCCCAAATGATGGTCTTCATCAATTCGGCGCGCAAAGACGATGATTTGCCGC
TAGAATATGTTGAAGGCTTTGTCAAAATGCTCGCACCGATCGCACCGCACTTGATGGAAGAAATCTGGCAACGGCTGGGA
CATGATCACAGCTTAACCTATGCGCCGTGGCCAAGTTATGATGAAAGCAAGCTTAAAACCGACACCTACGACATGATGGT
GCAGGTCAATGGCAAACTTCGTGGTTCCATCACTGCGAGCGTTGACGAGACTGATGACGAGATCAAACAAGCTGCTTTAG
CCAATGAAAATGTCCAGAAGTATACGACAGGCAAGGATATTAAAAAAATCATTGTCGTACCACGTAAGATTATTAATATC
GTTGCTAAGTAA

Protein sequence :
MAYDHHEIDKKWQRYWAEHNEFNTTTDPKKPNYYALDMFPYPSGQGLHVGHPEGYTATDIVARMKRMQGFNVLHPMGWDA
FGLPAEQYALNTGHNPRTFTKQNIETFKRQINSLGFSYDWNREINTTDPNYYKWTQWIFEQLYKHGLAYEAEVPVNWSPD
LGTVVANEEVIDGKTERGGFPVVRKPMRQWMLKITAYADKLLADLDDLDWPESIKQMQRNWIGKSTGAQITFTVTDTQEK
FDVFTTRPDTLFGATYVVMAPEHDLVEKITTPEQQAVVDAYIEEAAHKSDLDRTALDKEKTGVWTGAYATNPVNGEKLPI
WISDYVLATYGTGAIMAVPAHDDRDYAFAKKFGIEIKPVIEGGNIDEAAYTGDGVHINSGFLDGLNEQDAIDRMIAWLED
KGIGQAKVNYKLRDWVFSRQRYWGEPIPVIHWEDGETTLVPEDELPLTLPEEVDIKPSGTGESPLANLTDWVNVVDKNGR
KGKRETNTMPQWAGSSWYFLRFVDPHNKEALADYDKLKQWMPVDLYIGGAEHAVLHLLYARFWNLFLYDIGAIPNKEPFQ
RLFNQGMILGDNHEKMSKSKGNVVNPDDVVDEYGADTLRLYEMFMGPLDAGIAWSTDGLAGARKFLDRVWSAFIDDEGKL
RDRITTINDGRLDKVYNETVKKVTEDYEALHFNTAIAQMMVFINSARKDDDLPLEYVEGFVKMLAPIAPHLMEEIWQRLG
HDHSLTYAPWPSYDESKLKTDTYDMMVQVNGKLRGSITASVDETDDEIKQAALANENVQKYTTGKDIKKIIVVPRKIINI
VAK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 0.0 65