Gene Information

Name : serS (LGG_01893)
Accession : YP_003171639.1
Strain : Lactobacillus rhamnosus GG
Genome accession: NC_013198
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : -
Position : 1931359 - 1932642 bp
Length : 1284 bp
Strand : -
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGTTAGATCTCAAGTTGATTCGGCAAAAGCCGGAGTGGGCAAAAAAGAAGTTAGCTGCTCGCACGATCAAGGGTGAAGA
AATCGATGAATTAATCGCCCTTGATGAGAAACGACGTAAGGTAACAGTTCAAACCGAGGAGTTAAAGGCAAAGCGTAATG
AAGTTTCCGGCCAGATCGCGGTGATGAAACGGAACAAAGAAAACGCTGACGAGCAAATCACGGCTATGCGTGAAGTTGGT
CAAAAAATCAGCCAGTTAGATAAAGAATTAGCAGAACTGAATGAGAAAGTCACCTATATTCTGGTTCGGTTACCTAACTT
TCCGGCCGATGATGTCCCGATGTCACTAAATGAAGACGACTCGCGTGAAGAATATAAATGGGGCAACATTCCTCATTTTG
ATTTTCAACCGAAACATCATTGGGATATCGGCGAGAAACTAGGTATTTTGGACTTTGAACGGGCGGCCAAAGTATCAGGC
AGCCGCTTTGTCTACTATAAAGGTGCAGGTGCGCGACTAGAGCGAGCCGTTTATAACTTCTTCTTGGATGAACACCAAAA
AGAAGGTTATGAAGAAATTATTCCGCCATATTTGGTTAACAATGATTCAATGTTTGGCACAGGTCAATTTCCTAAGTTTA
CTGATGCAACGTACACCATCACAAACGATGGTGAGCCATTAACCATGATTCCAACCGCAGAAGTGCCGCTGGTCAATTAT
TATCGCGGGGATATTATCGATGCTGCTAAATTGCCAGTTAACTTCACCGCACTAACACCTGCCTTTCGTTCCGAAGCAGG
AAGCGCTGGTCGGGATACTCGTGGATTAATCCGGATGCATCAATTTAACAAGGTCGAAATGGTCAAGTTTTGCAAACCCG
AAGATTCCTGGCAAGAATTAAAGAATTTGATTCACGATGCAGAGGACTTGTTACGCAAGTTGGGCCTTCCATATCACGTC
ATCACCTTGGCCAGCAACGATGCCAGCTTTACGAGTGCTAAAACGAACGATCTTGAAGTGTGGTTCCCGGCGCAGAATCG
CTATCGTGAAATTTCGAGTTGCAGTAATTGCACGGATTTCCAGGCACGTCGAGCACAAATCCGTTATCGCGATGATGATG
GCAAGCTGCAATTTGTTCATACACTCAACGGTTCAGGCCTTGCAGTGGGACGGACTGTCGCTGCCATTCTTGAAAATTAT
CAGCAAGCTGATGGAACGGTTAAGATTCCTGACGTTCTGGTTCCCTACATGCACGGCCAAACTGCAATCAAGCAGGAAGA
TTAA

Protein sequence :
MLDLKLIRQKPEWAKKKLAARTIKGEEIDELIALDEKRRKVTVQTEELKAKRNEVSGQIAVMKRNKENADEQITAMREVG
QKISQLDKELAELNEKVTYILVRLPNFPADDVPMSLNEDDSREEYKWGNIPHFDFQPKHHWDIGEKLGILDFERAAKVSG
SRFVYYKGAGARLERAVYNFFLDEHQKEGYEEIIPPYLVNNDSMFGTGQFPKFTDATYTITNDGEPLTMIPTAEVPLVNY
YRGDIIDAAKLPVNFTALTPAFRSEAGSAGRDTRGLIRMHQFNKVEMVKFCKPEDSWQELKNLIHDAEDLLRKLGLPYHV
ITLASNDASFTSAKTNDLEVWFPAQNRYREISSCSNCTDFQARRAQIRYRDDDGKLQFVHTLNGSGLAVGRTVAAILENY
QQADGTVKIPDVLVPYMHGQTAIKQED

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 1e-128 61