Gene Information

Name : nrdE (LGG_01474)
Accession : YP_003171220.1
Strain : Lactobacillus rhamnosus GG
Genome accession: NC_013198
Putative virulence/resistance : Unknown
Product : ribonucleotide-diphosphate reductase subunit alpha
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0209
EC number : -
Position : 1478349 - 1480520 bp
Length : 2172 bp
Strand : +
Note : Catalyzes the rate-limiting step in dNTP synthesis

DNA sequence :
ATGTCACTAAAAACCATTAGTCCGGATGAGGTTACTTATTACGCACTTAACAACGAGATTAACATTCCCGTTAACGACCA
AATTCCGCTTAACAAAGATAAAGAAGCATTGCAGGCCTTTTTGACCGAAAATGTTGCACCCAATACCATGAAATTTGCTT
CATTACAGGAGCGCTTAAAGTATCTGGTTGAACATCACTATTATGAAGCCGACTTTTTAAAGAAATATCAACCAGCCTTT
TTGGAGAAGTTGAATCAGTTTCTCACTGCCCAGCATTTCCAATTTAAGTCGTTCATGGCTGCGTATAAATATTATGCTCA
GTACGCGTTAAAAACCGATGACGGAACGCAATATCTTGAAGATTACAAAGATCGCGTTTTCGCTAATGCCCTTTTCTTTG
CGGATGGTAACGAAGATTTGGCCGTTGACTTAGCCGATGAGATGATTCATCAGCGCTATCAGCCGGCTACCCCATCCTTC
CTGAATGCAGGTCGGGCGCGGCGTGGTGAACTGGTCTCTTGTTTCCTGTTGCAAATCACCGATGACATGAATTCAATTGG
CCGGGCAATCAACTCGGCTTTGGAACTTTCCCGTATCGGCGGCGGTGTCGGCTTGACACTGTCGAACCTGCGTGAAGCCG
GTGCACCGATCAAGGGCATTGACGGTGCTGCCAGTGGTGTCTTGCCGGTCATGAAGTTGCTGGAAGATTCATTCTCCTAC
AGTAACCAGCTGGGTCAGCGCCAAGGTGCCGGGGTTGTTTATTTGAACGTCTTCCATCCGGATATCATCAGCTTCCTAGG
CGCTAAGAAGGAAAATGCCGATGAAAAGTATCGGGTGAAAACGTTGAGCCTTGGTGTGATTGTGCCAGATAAATACTACG
AACTCATCAAGGCTAACGCTGACATGTACCTCTTCTCCCCTTATTCAGTCGAACGCGCGTATGGCAAGCCATTTTCTTAC
GTGGATATCACGAAGGAATACGACAAGATGGTAGCCAATCCTGATATTAAGAAATACAAGATTAAAGCGCGCGACTTGGA
AAACGAGATCTCCAAGTTGCAGCAAGAATCCGGCTATCCATACATCATTAATATCGATACAGCCAATCGTGCCAATCCGA
TCGAAGGTAAGATTATCATGAGCAACCTGTGTTCTGAGATTATGCAGGTTCAGGTTCCGTCTAAGCTCAATAATCGTCAG
GAGTACGAGGTCTTAGGGACAGATGTTTCATGCAACCTGGGGAGTACGAATATTCCTAACCTGATGCACAGCCGTGATTT
TGGTCATAGCGTCGAAGCCATGGTACGCGCGCTCACTTATGTCACGGATCACAGCAACATTGACGTTGTGCCGTCCGTGC
AGCACGGCAATCACCTTGCTCACAGCATTGGTCTTGGTGCGATGGGCCTGCATACCTATTTTGCCAAGAACCACATGTAT
TATGGTTCACCGGAAAGCCTGGATTTCACTAACATCTACTTCCTACTGCTTAATTACTACACGCTCAAAGCTTCCAATAA
GATCGCTAAGGAACGCGGCGAATCCTTCCACAACTTTGAAAATAGCAAGTACGCAGATGGCAGTTATTTTGACAAGTATC
TCAATCAAACTTGGGCGCCGAAGTACGATAAAGTTCGCGACTTGTTCAAAAACATTCACATTCCAACGCAGGCTGATTGG
CAGGCACTTAAAGAAGATGTGATGAAAAACGGTTTGTACCATCAAAACCGGATGGCAGTTGCACCTAATGGCTCAATTAG
CTATATCAACGACACCAGCGCTTCATTGCAGCCAATTGTCAACCGGATTGAGGATCGTCAGGAAAAGAAAATCGGTACCA
TTTATTACCCGGCACCGGGACTGTCCAATGATACGATGCCTTACTATCAAAGCGCCTATGACATTGATATGCGTAAAGTG
ATCGATGTTTATGCCGCTGCGCAACAACATGTTGACCAAGGAATGGCGATGACGTTGTTTATGCGCAGTACCATCCCAGC
CGGACTTTATCCGTGGAAAGATGGACGCACGAATAAAATGACTACCCGGGACTTGAACATCTTGCGGAATTACGCTCATT
ATAAGGGCATTAAGTCCATTTACTACATCCGGACTTATACCGATGACCAAGAAGAAATCGGCAGCAACGCTTGTGAAAGT
TGCTCAATTTGA

Protein sequence :
MSLKTISPDEVTYYALNNEINIPVNDQIPLNKDKEALQAFLTENVAPNTMKFASLQERLKYLVEHHYYEADFLKKYQPAF
LEKLNQFLTAQHFQFKSFMAAYKYYAQYALKTDDGTQYLEDYKDRVFANALFFADGNEDLAVDLADEMIHQRYQPATPSF
LNAGRARRGELVSCFLLQITDDMNSIGRAINSALELSRIGGGVGLTLSNLREAGAPIKGIDGAASGVLPVMKLLEDSFSY
SNQLGQRQGAGVVYLNVFHPDIISFLGAKKENADEKYRVKTLSLGVIVPDKYYELIKANADMYLFSPYSVERAYGKPFSY
VDITKEYDKMVANPDIKKYKIKARDLENEISKLQQESGYPYIINIDTANRANPIEGKIIMSNLCSEIMQVQVPSKLNNRQ
EYEVLGTDVSCNLGSTNIPNLMHSRDFGHSVEAMVRALTYVTDHSNIDVVPSVQHGNHLAHSIGLGAMGLHTYFAKNHMY
YGSPESLDFTNIYFLLLNYYTLKASNKIAKERGESFHNFENSKYADGSYFDKYLNQTWAPKYDKVRDLFKNIHIPTQADW
QALKEDVMKNGLYHQNRMAVAPNGSISYINDTSASLQPIVNRIEDRQEKKIGTIYYPAPGLSNDTMPYYQSAYDIDMRKV
IDVYAAAQQHVDQGMAMTLFMRSTIPAGLYPWKDGRTNKMTTRDLNILRNYAHYKGIKSIYYIRTYTDDQEEIGSNACES
CSI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cur_1481 YP_001800875.1 ribonucleotide-diphosphate reductase subunit alpha Not tested Not named Protein 1e-177 53