Gene Information

Name : pyk (LGG_01375)
Accession : YP_003171121.1
Strain : Lactobacillus rhamnosus GG
Genome accession: NC_013198
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : -
Position : 1378301 - 1380067 bp
Length : 1767 bp
Strand : +
Note : -

DNA sequence :
ATGAAAAAAACCAAGATCGTCAGCACACTTGGACCTGCAAGTAACACCACTGATATCATCGTTAAGTTGATTGAAGCGGG
TGCCAACGTTTTCCGTTTCAACTTCTCACATGGTGATCACGAAGAGCATTTGGCACGGATGAACATGGTTCACGAAGCTG
AAAAGATCACGGGCAAAACCGTTGGTATCATGCTTGATACAAAGGGTGCCGAAATTCGGACGACTGTTGAGGATACCCCT
AATGGCAAGATTGAATTCCATACGGGCGATAAGGTTCGTATCTCCATGGATGCAAGCCTGAAGGGTACTAAGGAAAAGGT
TGCCGTTACTTATCCTGGTCTTTATGATGATACCCATGTTGGTGGCCACGTTTTGTTCGATGATGGCTTGATCGACATGA
AGATCACCGAAAAAGATGAGAAGAACCGCGAACTTGTCACCGTTGTTCAAAATGACGGTGTTCTTGGTGGCAAGAAAGGG
GTCAACGCACCTGGTGTTGCGATCAACTTGCCAGGTATCACAGAGAAGGATTCCAACGATATTCGTTTTGGTCTGGACAA
TGGCATTAACTTTATTGCTGCATCCTTCGTTCGTAAGCCTCAAGATGTTTTGGACATTCGTGAACTCCTTGAAGAAAAGA
ACGCACTTAATGTCCAAATCTTCCCTAAGATCGAATCTCAAGAAGGTATCGACAATATCGATGACATCTTGAAAGTGTCT
GACGGCTTGATGGTTGCTCGTGGCGACATGGGTGTTGAAATTCCGTTTGAACATGTTCCGATCGTTCAAAAGCGCTTGAT
CAAGAAGTGCAACGCTTTGGGCAAACCGGTTATTACCGCTACCCAGATGTTGGATTCCATGCAGGAAAACCCACGTCCTA
CTCGTGCCGAAGTTAATGACGTTGCTAACGCTGTTTTTGATGGCACCGATGCAACCATGCTTTCCGGTGAATCTGCTAAT
GGTGAATATCCAGTTGAATCTGTTGCTGCAATGGCACGGATTGATGAATACACCGAAGCAGCTATGCAGGATCAGGATGC
TTTTGCATTGAAGGAATACAGTAACAAGAACATTACCGAAGCAGTAGGTCAGAGTGTTGCACACACGGCTCGTAACCTTG
GTGTTAAGACCATTGTTGCTGCTACTGAATCTGGCTACACCGCACGGATGATCTCCAAGTATCGTCCTAAGGCTGATATT
CTTGCGATTACCTTCAGTGAAAAGACTCAGCGTGGTTTGATGGTCAACTGGGGTGTTTATCCTATTGTTGCCGACAAGCC
TGCCAACACTGATGCAATGTTTGACTTGGCTACCAAGAAGGCTCAAGATCTTGGCTTTGCTAAGGAAGGCGACTTGATTC
TGATTACAGCCGGTGTTCCAGTTGGCGAATCAGGTACGACTAATGTCATGAAGGTTCAACTGATCGGTTCCAAGCTGGTT
CAAGGCTCTGGTGTCGGTGATGAATCTACAATCGGTAAAGCTGTCATTGCAAGCAACGCTCAGGAAGCCGCTGCCAAGAT
GCAAAAAGGCGACATTCTGGTTGTTAAGACAACTGACAAAGATTACCTGCCAGCAATCGAAAAGGCCGCTGCCTTGGTTG
TTGAAACAGGCGGCTTGACCAGTCACGCTGCTGTTGTCGGCATCGCGATGGGTATTCCGGTTGTCGTTGGTGCTGAAAAT
GCTACCAGCGTTATCTCTGATGGTCAGATTATCACCGTTGATTCACGTCGCGGGATTGTCTACAAGGGTGCTACTAACGC
ACTTTAA

Protein sequence :
MKKTKIVSTLGPASNTTDIIVKLIEAGANVFRFNFSHGDHEEHLARMNMVHEAEKITGKTVGIMLDTKGAEIRTTVEDTP
NGKIEFHTGDKVRISMDASLKGTKEKVAVTYPGLYDDTHVGGHVLFDDGLIDMKITEKDEKNRELVTVVQNDGVLGGKKG
VNAPGVAINLPGITEKDSNDIRFGLDNGINFIAASFVRKPQDVLDIRELLEEKNALNVQIFPKIESQEGIDNIDDILKVS
DGLMVARGDMGVEIPFEHVPIVQKRLIKKCNALGKPVITATQMLDSMQENPRPTRAEVNDVANAVFDGTDATMLSGESAN
GEYPVESVAAMARIDEYTEAAMQDQDAFALKEYSNKNITEAVGQSVAHTARNLGVKTIVAATESGYTARMISKYRPKADI
LAITFSEKTQRGLMVNWGVYPIVADKPANTDAMFDLATKKAQDLGFAKEGDLILITAGVPVGESGTTNVMKVQLIGSKLV
QGSGVGDESTIGKAVIASNAQEAAAKMQKGDILVVKTTDKDYLPAIEKAAALVVETGGLTSHAAVVGIAMGIPVVVGAEN
ATSVISDGQIITVDSRRGIVYKGATNAL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 1e-90 48
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 2e-90 48
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 9e-91 48
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 9e-91 48

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pyk YP_003171121.1 pyruvate kinase VFG0479 Protein 4e-91 48