Gene Information

Name : pdhD (LGG_01323)
Accession : YP_003171069.1
Strain : Lactobacillus rhamnosus GG
Genome accession: NC_013198
Putative virulence/resistance : Unknown
Product : dihydrolipoamide dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1249
EC number : -
Position : 1320182 - 1321585 bp
Length : 1404 bp
Strand : +
Note : E3 component of pyruvate complex; catalyzes the oxidation of dihydrolipoamide to lipoamide

DNA sequence :
ATGGTTGTAGGCGATTTTGCAATCGATTTGGACACCGTTGTGATTGGCTCTGGCTCAGGTGGTTACGTAGCTGCGATCCG
AGCAGCCGAAATGGGTCAGAAGGTAACTGTTATCGAGAATACCTTCATTGGCGGGGTTTGTTTGAATGTTGGCTGTATCC
CATCAAAAGCTTTGATCAATGCCGGTCACCGTTATCAAGATGCCTTGGAAGCAAGCACGTTTGGTATTAATGCCAAGGGC
GCGGATCTTGATTTCAAAAAAACCCAGGATTGGAAGCAAAACAAGGTTGTGCACACGTTAACCAGCGGTGTTGCGATGCT
TTTAAAAAAGCACAAAATCGAAACCATCATGGGGACGGCTTTCTTGAAAGATGATCATAGTCTGCGGGTTATGCAAAAAG
ACTCGGCTCAGACATACACCTTCAAGAATTTGATCATTGCAACCGGAAGCCGGCCAATTGAAATCAAAGGCTTCAAATTT
GGCAAACGGATTTTGGATTCAACCGGTGGCCTAAACTTACCGGAAGTACCAAAAGAATTCGTGGTGATTGGCGGTGGCTA
CATCGGATCCGAACTGGCGAGCGCCTATGCCAACTTAGGCGCACATGTCACAATTCTTGAAGGCACCAGCTCAATTTTGC
CAAACTTTGAAAAGGATATGGTTCAACTCGTCTTGAACTCCTTTAAAAAGCGCGGCGTTACAGTGATTACCAACGCGATG
GCGAAGGAAGCCGAAGATACCGGCAATGGCGTCAAGGTAACCTATACAGCGGACGGTAAAGAACAAACCATTGCCGCAGA
TTATGTGATGGTCACAGTCGGGCGGCGGCCAAATACCGATGATTTGGGCTTAGACATTGTTGGCATTGAAACAACGGATC
GCGGCTTGATCAAAGTCGATGCGCAAGGACGAACCAATAAGCCTAATATTTTTGCAATCGGTGACATTGTTCCCGGTGCT
GCATTAGCGCATAAAGCAAGTTACGAAGGTAAGATAGCGGCTGAGGCGATCAGTGGCAAGGCAAGCGCGGTTGACTATAA
AGCAATGCCGGCTGTTTGTTTCACGGATCCAGAACTGGCTACAACTGGCATGACGCTTGCTGAGGCCAAGGATAAAGGCA
TTAAAGCTAAAGCAAGCAAGTTTCCATTTGCGGCGAATGGCCGTGCTTTAAGTTTGGCGCAAACCGAGGGCTTCGTTCGT
CTGGTTACGGATGAAAACGGAACCGTCATCGGTGGTCAAGTTGCTGGTGCCGGTGCCAGTGATTTGATCTCAGAATTAAC
GGTCGCGGTTGAAGGTGGACTTAACGCTGAAGATTTGGCTTTGACCATCCATCCACATCCGACCTTAAGTGAAACCATTA
TGGATGATGCTGAAGTTGCATTAGGGTTGCCAATTAATATCTAG

Protein sequence :
MVVGDFAIDLDTVVIGSGSGGYVAAIRAAEMGQKVTVIENTFIGGVCLNVGCIPSKALINAGHRYQDALEASTFGINAKG
ADLDFKKTQDWKQNKVVHTLTSGVAMLLKKHKIETIMGTAFLKDDHSLRVMQKDSAQTYTFKNLIIATGSRPIEIKGFKF
GKRILDSTGGLNLPEVPKEFVVIGGGYIGSELASAYANLGAHVTILEGTSSILPNFEKDMVQLVLNSFKKRGVTVITNAM
AKEAEDTGNGVKVTYTADGKEQTIAADYVMVTVGRRPNTDDLGLDIVGIETTDRGLIKVDAQGRTNKPNIFAIGDIVPGA
ALAHKASYEGKIAAEAISGKASAVDYKAMPAVCFTDPELATTGMTLAEAKDKGIKAKASKFPFAANGRALSLAQTEGFVR
LVTDENGTVIGGQVAGAGASDLISELTVAVEGGLNAEDLALTIHPHPTLSETIMDDAEVALGLPINI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SE0077 NP_763632.1 dihydrolipoamide dehydrogenase component of pyruvate dehydrogenase E3 Not tested SCCpbp4 Protein 2e-103 48