Gene Information

Name : hemC (CAP2UW1_0791)
Accession : YP_003166065.1
Strain : Candidatus Accumulibacter phosphatis UW-1
Genome accession: NC_013194
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 916830 - 917777 bp
Length : 948 bp
Strand : +
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
TTGAACTCTGCAAACCAAGCCCCGCCGCGCCTGGTCATCGCCTCGCGTGAATCGCGTCTTGCCATGTGGCAGGCTCAGCA
CGTCAGCGGTCGCCTTACGGAGTTGTACCCACAGACGGCCGTCGACATCCTCGGCATGACGACGCGGGGCGATCAGATCC
TCGATCGTCCGCTTGCTGCGATCGGCGGCAAAGGCTTGTTCATCAAGGAACTCGAGGTGGCCATGCAACAGGGCCGCGCT
GATCTCGCGGTGCATTCGATGAAGGACCTGCCGATGGAGATGCCCGAGGGTTTTGCCTTGGCCGCCATCTCCGTGCGTGA
GAATCCGTGCGATGCTTTCGTCTCGAACCGGTTTGGCGGGCTCGCCGAACTGCCGGCCAATGCCGTGGTCGGTACGTCCA
GCCTGCGGCGCGAAGCCATGCTGCGCGCGGGCTATCCGCAACTCGAGATCAGGAGCTTGCGCGGCAATCTCGATACGCGT
CTGCGGAAGCTCGATGCCGGAGACTACGATGCGATCATCCTCGCCGCCGCCGGTCTGATCCGGCTGGGGCTGACCGACAG
GATCAAGGCCGTGCTGACGCCCGAGCAGTCCCTGCCGGCACCCGGGCAAGGTGTGCTGGGTATCGAGGTCCTCTCGGCGC
GCGTCGACCTGTTGACTCTGGTGGCACCCCTCAACGATGTCGCCACAGCTCACTGCGTGCGTGCCGAGCGTGCTTTCTCG
CGTGCTCTCGGCGGCAGCTGCCAGATTCCTCTGGCCGCGCATGCCGTACTCGACAGCGGTGCCTTGTGGCTGCGCGGCTG
GATTGCGACGCCGGACGGCCGCCACAGCCTGAGTGGCGAACTGCGCGGACTGCCGGAAGACGACGAGTCGATCGGTTGCC
GGCTCGCTCAGGCGCTCCATGAACGCGGTGCCGATGCGATTCTTCGGGAACTGGCAACTGGCCAATGA

Protein sequence :
MNSANQAPPRLVIASRESRLAMWQAQHVSGRLTELYPQTAVDILGMTTRGDQILDRPLAAIGGKGLFIKELEVAMQQGRA
DLAVHSMKDLPMEMPEGFALAAISVRENPCDAFVSNRFGGLAELPANAVVGTSSLRREAMLRAGYPQLEIRSLRGNLDTR
LRKLDAGDYDAIILAAAGLIRLGLTDRIKAVLTPEQSLPAPGQGVLGIEVLSARVDLLTLVAPLNDVATAHCVRAERAFS
RALGGSCQIPLAAHAVLDSGALWLRGWIATPDGRHSLSGELRGLPEDDESIGCRLAQALHERGADAILRELATGQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 5e-60 53
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 5e-60 53