Gene Information

Name : CAP2UW1_4292 (CAP2UW1_4292)
Accession : YP_003169457.1
Strain : Candidatus Accumulibacter phosphatis UW-1
Genome accession: NC_013194
Putative virulence/resistance : Virulence
Product : N-6 DNA methylase
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG0286
EC number : -
Position : 4886047 - 4888356 bp
Length : 2310 bp
Strand : +
Note : PFAM: N-6 DNA methylase; KEGG: glo:Glov_2201 N-6 DNA methylase

DNA sequence :
ATGGACCAGGCGACCCACAACAAGATCGTCTCCTTCATCTGGGGCATCGCTGACGACGTCCTGCGCGATCTCTTCAAGCG
CGGCAAGTACCCGGACGTGATCCTGCCGATGTGCGTCATCCGGCGCATGGATGCGGTCCTCGAACCGACCAAGCAGAGCG
TGCTCGACACGCGCAGGATGCTCGACGCGGCGGGCATCACCGAGCAGCGCGCCGCGCTCTGCGATGCCGCCGGCCAAGCC
TTCTACAACACCTCGCGTTTCACCCTGCGCGACCTCAAGTCGCGCGGCAGCCAGCAGCGGCTGCTGGCCGACTTCGAGGA
CTATCTCAACGGTTTCTCGGCCAACGTCCAGGACATCCTCGACAACTTCAAATTCCGCAACCAGTTGCAGACGCTGTCCA
GGGCCGACGCCATCGGCACGCTGATCAACAAGTTCCTCGACCCCGACATCGACCTCTCGCCGGCCGGCATCGACAACCAT
TCGATGGGCACCGTCTTCGAGGAACTGGTGCGCAAGTTCAACGAGGAGAACAACGAAGAAGCGGGTGAGCACTGGACGCC
GCGCGACGCGGTGCGCCTGATGGCGAACTTGGTGTTCCGCCCGATCGAGTCCGCGATCCGGTCCGGCACCTACCTGCTTT
ACGACTGCGCCTGCGGCACCGGCGGCATGCTCACCGTCGCCGAGGAGACGCTGACGGCGATCGCCGCCGGGCGCGGCCAG
CAGGTCAGGTGCCTGCTCTACGGCCAGGAGATCAACCCCGAGACCTACGCCGTCTGCAAGGCCGACATGCTGCTCAAGGG
CGAAGGCGAGAGCGCCGACCACATCGTCGGTGGCGCCGAGTGGTCCACGCTGGCGCACGACGCCTTCCCCGCCCGCGAGT
TCGACTTCATGCTCGCCAACCCGCCCTACGGCAAGAGCTGGAAGAAGGATCTGGAAGCCATGGGCGGCAAGGACGGCATG
CGCGACCCGCGCTTCAAGGTCATGCACCAGGGCGAGGAGCTTTCGCTGGTCACGCGTTCGAGCGACGGGCAAATGCTCTT
CCTCGCCAACATGGCGTCCAAGATGAACGGTCAGTCGGCCCTCGGCAGCCGCATCGCTGAGGTGCACAACGGCAGTTCGC
TGTTCACCGGCGACGCCGGCCAGGGCGAGAGCAACATCCGCCGCTGGCTGATCGAGAACGACTGGCTCGAAGCCATCGTC
GCGCTGCCGCTCAACCTCTTCTACAACACCGGCATCGCCACCTACATCTGGGTGCTCTCCAACCGGAAACCCGCCCACCG
CCAGGGCCGGGTGCAGCTCATCGACGCCAGCCAGTGGTTCAAGCCGCTGCGCAAGAACCTCGGCAAGAAGAACTGCGAAC
TCTCGCCCGAGGACATCGAGCGCATCAGCCGCAGCTTCCTCGACTTCGCGGAAACGCCCGAGTCGAAGATCTTCCCGAAT
GCCGCCTTCGGCTACTGGAAGGTCACCGTCGAGCGCCCGTTGCGCCTGTACAGCCAGCTTTCGCTCAAGGCCATCGAAAC
GCTGCGCTTCAACTCCGGCGACGAGGACCTGCGCGCCACGCTCTACGAGGAGTTCGGCGACGACCTGTTCACCCGTTTCT
CCGCGGTTTCCGCTGCACTTGAGAAACGCCTCGCCGACTGGGGCAGCAGCGACGACTCCGAAGGCGAAGACGACGAGGGC
GGCGGCACGAAGAAGGGTCTGCCCGAACGGCAGAAGAAGAAGCTGCTCGACGCCAGAACCTGGGAACGCGACGGCCGCCT
GGTGGACGTGGCTACCCGGCTGCGCGTGCTGCTCGGCGAGGCGCTCTTCGACGATCACAACGCCTTCCGCGACCGCGTGG
ATACGGCACTGAAGGCGGCCGGGATCAAACTCGCCGCCGCCGATCTGAAGCAGATCCTGAAGGTCGTGAGCTGGCGCGAC
GAGAGCGCACCGCCGGTCATCGCCAGGGTGCACAAGCCCGGCAAGCTCAGGGCCGAGCCGCTGCGCGGTTTCTACGAGGC
GACCGTGGACGGCAGGTCCTCCATCGTCGAGTACGAACCCGACGCCGACCTGCGCGATACCGAGCAGGTGCCGCTGCTCG
AAGACGGCGGCATCGCGGCCTTCATTCGCCGCGAGGTGCTGCCGTACACGCCAGACGCATGGATCAAGGAAGACGCCACC
AAGATCGGCTACGAGATCAGCTTCACGCGCCACTTCTACAAGCCGCAGCCGCTGCGCACGCTCGAAGAGATCAGCGCCGA
CATCCTGGCCATCGAGAAGGAAGCTGAGGGCTTGCTGGACGGCCTCCTGATCGGCGGGAAACGCGCATGA

Protein sequence :
MDQATHNKIVSFIWGIADDVLRDLFKRGKYPDVILPMCVIRRMDAVLEPTKQSVLDTRRMLDAAGITEQRAALCDAAGQA
FYNTSRFTLRDLKSRGSQQRLLADFEDYLNGFSANVQDILDNFKFRNQLQTLSRADAIGTLINKFLDPDIDLSPAGIDNH
SMGTVFEELVRKFNEENNEEAGEHWTPRDAVRLMANLVFRPIESAIRSGTYLLYDCACGTGGMLTVAEETLTAIAAGRGQ
QVRCLLYGQEINPETYAVCKADMLLKGEGESADHIVGGAEWSTLAHDAFPAREFDFMLANPPYGKSWKKDLEAMGGKDGM
RDPRFKVMHQGEELSLVTRSSDGQMLFLANMASKMNGQSALGSRIAEVHNGSSLFTGDAGQGESNIRRWLIENDWLEAIV
ALPLNLFYNTGIATYIWVLSNRKPAHRQGRVQLIDASQWFKPLRKNLGKKNCELSPEDIERISRSFLDFAETPESKIFPN
AAFGYWKVTVERPLRLYSQLSLKAIETLRFNSGDEDLRATLYEEFGDDLFTRFSAVSAALEKRLADWGSSDDSEGEDDEG
GGTKKGLPERQKKKLLDARTWERDGRLVDVATRLRVLLGEALFDDHNAFRDRVDTALKAAGIKLAAADLKQILKVVSWRD
ESAPPVIARVHKPGKLRAEPLRGFYEATVDGRSSIVEYEPDADLRDTEQVPLLEDGGIAAFIRREVLPYTPDAWIKEDAT
KIGYEISFTRHFYKPQPLRTLEEISADILAIEKEAEGLLDGLLIGGKRA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC1769 NP_231404.1 DNA methylase HsdM Not tested VPI-2 Protein 3e-154 45
VC0395_A1367 YP_001217310.1 DNA methylase HsdM Not tested VPI-2 Protein 3e-154 45
VPI2_0017c ACA01834.1 DNA methylase HsdM Not tested VPI-2 Protein 2e-153 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
CAP2UW1_4292 YP_003169457.1 N-6 DNA methylase VFG1102 Protein 1e-154 45