Gene Information

Name : CAP2UW1_3803 (CAP2UW1_3803)
Accession : YP_003168982.1
Strain : Candidatus Accumulibacter phosphatis UW-1
Genome accession: NC_013194
Putative virulence/resistance : Virulence
Product : flagellar protein export ATPase FliI
Function : -
COG functional category : N : Cell motility
COG ID : COG1157
EC number : 3.6.3.15
Position : 4348903 - 4350321 bp
Length : 1419 bp
Strand : +
Note : KEGG: dar:Daro_0770 ATPase FliI/YscN; TIGRFAM: ATPase, FliI/YscN family; flagellar protein export ATPase FliI; PFAM: H+transporting two-sector ATPase alpha/beta subunit central region; SMART: AAA ATPase

DNA sequence :
ATGAGTGAACCCGCCGCCAACCCGCATCTCGCCAATTGGCGCCACTTCCTCGATGGTTGCCGAGGCGCCGCCGGCCAGGT
GAATTCGCTGCTGCCGAGCGGCCACCTGACGCGCATCAACGGCCTCGTGATGGAGGCGTCCGGACTGAAACTGCCCCTCG
GCAGCTCATGCCGCATCACGCCGCTTGGCGGCTCGCCGATCGAAGCGGAAGTGGTCGGCTTCAACGGCGAGCGGCTGTTC
CTGATGCCGTCGGAAGATGTCTATGGCCTGTCGCCAGGGGCCCGCGTCGTCGCCCTCGAAACGCGCCACCCGCCACCGCA
GATCGGTCGTCTGCCGCCTGCACGGCGACGCTCGATCGACCGCGCCAAACTGGTGCCGGTCGGCGAATCCCTCCTTGGCC
GCGTCCTCGATGGGGCCGGCCGGCCGCTCGACAAGCTTGGTCCGTTGCATGCCAGGTCACTGCGCCCGCTGCAGAGCCGG
CCGGTCAACCCGATGTCGCGGGCGCCGATCGACAAGGCGCTGGACGTCGGGGTGCGTGCCATCAATGGCCTGCTCTGTGT
CGGACAGGGACAACGGATGGGCCTGTTTGCCGGATCGGGTGTCGGCAAGAGCGTACTGCTCGGCATGATGGCCCGCTACA
CGGAGGCGGAAATCATCGTCGTCGGCCTCATCGGCGAGCGCGGTCGTGAGGTCAAGGAGTTCATCGAGCAGATCCTTGGT
GAGGAAGGCCTGCGCCGATCCGTCGTCATCGCCGCACCGGCCGACGTCAGTCCCTTGATGCGGCTGCAGGGTGCGGCCTA
TGCGACGTGCATTGCCGAGTATTTCCGTGACCGGGGCCGGCATGTCCTGCTGATCATGGATTCGCTGACGCGCTACGCCA
TGGCGCAACGCGAGATAGCGCTCGCCATCGGCGAGCCGCCGGTCACCCGCGGCTACCCCCCATCGGTTTTCGCGCGCCTG
CCGCAATTGGTGGAGCGGGCGGGCAATGGCGCCGACGGCGGCGGCTCGATCACCGGCTTCTATACCGTTCTCGCCGAAGG
CGACGACCAGCAGGATCCGATCGCCGATGCCGCGCGAGCGATCCTTGACGGACACATCGTACTGTCGCGAACCCTGGCCG
ATGCCGGCCACTACCCGGCAATCGACATCGAGCAATCGATTTCACGGGCCATGGTCAACCTGGTCAGCCCCGGTCATCTG
GAACAGATTCGAAATTTCAAGCGACTGTTTTCGCGCTACCAGCGCTCACGCGATCTGATCAGCGTCGGCGCCTATGCCGC
GGGGTCCGACCCACAACTCGACCAGGCGATAGCCATCTATCCGCGCTTCGAGTCATTCCTGCAGCAGAGTCTGGCCCAAC
CCGCGGACTTCGCCAGCAGTCTGCGTGAGTTGCAGGCACTGTTTGGCGTCGCTGCCTGA

Protein sequence :
MSEPAANPHLANWRHFLDGCRGAAGQVNSLLPSGHLTRINGLVMEASGLKLPLGSSCRITPLGGSPIEAEVVGFNGERLF
LMPSEDVYGLSPGARVVALETRHPPPQIGRLPPARRRSIDRAKLVPVGESLLGRVLDGAGRPLDKLGPLHARSLRPLQSR
PVNPMSRAPIDKALDVGVRAINGLLCVGQGQRMGLFAGSGVGKSVLLGMMARYTEAEIIVVGLIGERGREVKEFIEQILG
EEGLRRSVVIAAPADVSPLMRLQGAAYATCIAEYFRDRGRHVLLIMDSLTRYAMAQREIALAIGEPPVTRGYPPSVFARL
PQLVERAGNGADGGGSITGFYTVLAEGDDQQDPIADAARAILDGHIVLSRTLADAGHYPAIDIEQSISRAMVNLVSPGHL
EQIRNFKRLFSRYQRSRDLISVGAYAAGSDPQLDQAIAIYPRFESFLQQSLAQPADFASSLRELQALFGVAA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 2e-73 49
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 2e-73 49
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 3e-83 47
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 3e-83 47
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 9e-86 47
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 7e-86 47
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 7e-86 47
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-83 47
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 1e-83 47
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 2e-82 47
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 8e-72 47
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 5e-72 47
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 1e-72 47
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 3e-72 47
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 1e-72 47
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-84 46
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 4e-85 46
lscN AAO18044.1 LscN Virulence TTSS locus Protein 1e-80 44
unnamed AAL06369.1 EscN Virulence LEE Protein 1e-73 44
spaI NP_457288.1 secretory apparatus ATP synthase (associated with virulence) Virulence SPI-1 Protein 1e-63 44
spaI NP_806497.1 ATP synthase SpaL Virulence SPI-1 Protein 1e-63 44
invC NP_461815.1 ATP synthase SpaL Virulence SPI-1 Protein 1e-63 44
invC YP_217813.1 ATP synthase SpaL Virulence SPI-1 Protein 1e-63 44
hrcN AAT96258.1 HrcN Virulence S-PAI Protein 8e-68 43
hrcN AAT96299.1 HrcN Virulence S-PAI Protein 5e-68 43
escN AAK26715.1 EscN Virulence LEE Protein 6e-73 43
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 2e-73 43
escN AAL57542.1 EscN Virulence LEE Protein 6e-73 43
escN CAC81862.1 EscN protein Virulence LEE II Protein 2e-73 43
escN AAC38383.1 EscN Virulence LEE Protein 1e-73 43
hrcN AAR25633.1 type III secretion cytoplasmic ATPase HrcN Not tested Not named Protein 7e-64 43
escN AAC31513.1 L0034 Virulence LEE Protein 9e-74 43
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 9e-74 43
escN YP_003223475.1 translocator EscN Virulence LEE Protein 2e-73 43
escN NP_290268.1 hypothetical protein Virulence LEE Protein 1e-73 43
ECs4568 NP_312595.1 EscN Virulence LEE Protein 1e-73 43
escN YP_003236088.1 translocator EscN Virulence LEE Protein 8e-74 43
escN CAI43874.1 EscN protein Virulence LEE Protein 1e-73 43
hrcN AAB06001.1 HrcN Virulence Hrp PAI Protein 7e-69 43
invC AAS66861.1 InvC Not tested SSR-2 Protein 8e-62 43
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 4e-66 42
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 2e-67 42
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 3e-63 42
ECs3730 NP_311757.1 ATP synthase SpaL Not tested LIM Protein 3e-60 42
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 6e-66 41
hrcN ABA47275.1 HrcN Virulence S-PAI Protein 2e-69 41
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 1e-64 41
hrcN ABQ88354.1 HrcN Virulence Hrp PAI Protein 7e-60 41
hrpJ4 AAA81942.1 HrpJ4 Virulence Hrp PAI Protein 7e-60 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
CAP2UW1_3803 YP_003168982.1 flagellar protein export ATPase FliI VFG2499 Protein 1e-150 68
CAP2UW1_3803 YP_003168982.1 flagellar protein export ATPase FliI VFG2331 Protein 2e-131 65
CAP2UW1_3803 YP_003168982.1 flagellar protein export ATPase FliI VFG1254 Protein 3e-126 60
CAP2UW1_3803 YP_003168982.1 flagellar protein export ATPase FliI VFG0515 Protein 2e-72 47
CAP2UW1_3803 YP_003168982.1 flagellar protein export ATPase FliI VFG0390 Protein 8e-82 45
CAP2UW1_3803 YP_003168982.1 flagellar protein export ATPase FliI VFG0192 Protein 7e-83 44
CAP2UW1_3803 YP_003168982.1 flagellar protein export ATPase FliI VFG0048 Protein 8e-84 44
CAP2UW1_3803 YP_003168982.1 flagellar protein export ATPase FliI VFG2144 Protein 5e-81 44
CAP2UW1_3803 YP_003168982.1 flagellar protein export ATPase FliI VFG0555 Protein 6e-64 44
CAP2UW1_3803 YP_003168982.1 flagellar protein export ATPase FliI VFG1778 Protein 1e-61 44
CAP2UW1_3803 YP_003168982.1 flagellar protein export ATPase FliI VFG0730 Protein 8e-74 43
CAP2UW1_3803 YP_003168982.1 flagellar protein export ATPase FliI VFG0812 Protein 5e-74 43