Gene Information

Name : Lebu_0874 (Lebu_0874)
Accession : YP_003163773.1
Strain : Leptotrichia buccalis DSM 1135
Genome accession: NC_013192
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : -
Position : 955370 - 956797 bp
Length : 1428 bp
Strand : +
Note : catalyzes the formation of phosphoenolpyruvate from pyruvate

DNA sequence :
ATGAAAATTAAAATGACTAAAGTTGTTTGTACCATCGGTCCAAAAACTGAAAGTATTGAAATGTTGACAAAATTAGTAGA
AAGTGGAATGAACGTAATGAGATTGAACTTTTCTCATGGTGATTTTGAAGAACATGGACAAAGAATTAAAAATATTAGAG
AAGTAATGAAAAAAACAGGTAAAGAAATAGGGATTTTATTAGATACTAAAGGGCCTGAAATTAGAACTGGAAAATTAGAA
GGTGGAAAAGATGTATTATTAGAAACTGGTAAAAAAGTAACTATTACTACTGATTATTCTTTCGTTGGAAATGCTGAAAA
ATTTGCAGTTTCTTATCCTGGAATTGTTGATGACTTATATGAAGGAACAACAGTTTTATTAGATGATGGTTTAGTTGGAT
TAAAAGTTGAGAGCGTAGACAAAGCAGCTGGAGAAGTTCACTGTGTTATCACAAATACTGGAGAATTAGGAGAAACTAAA
GGTGTAAACTTGCCAGATGTTTCAGTTGGATTGCCTGCATTAGCTGAAAAAGATATTGCTGACTTGAAATTTGGTTGTGA
ACAAGGTGTTGACTTTGTAGCAGCTTCATTCATAAGAAAAGCATCTGACGTTGCTGAAGTAAGAAAAGTATTAGATGATA
ATGGTGGAAAAAATATTCAAATTATTCCTAAAATTGAAAGCCAAGAAGGTGTTGACAACTTCGATGAAATCTTGGAATTA
AGTGATGGAATCATGGTAGCAAGAGGAGATTTAGGAGTAGAAGTTCCTGCAGAAGAAGTTCCTTTCATGCAAAAAATGAT
GATTAGAAAATGTAACAAAGCTGGAAAACCAGTTATTACAGCTACACAAATGTTAGATTCAATGATTAGAAACCCAAGAC
CTACAAGAGCAGAAGCAGGAGACGTTGCTAATGCTATTTTAGATGGAACAGATGCAGTTATGTTATCAGGAGAATCAGCA
AAAGGTAAATATCCAGTAGAAGCTGTTAAGATGATGGCTACTATTTCAAAAAGAACAGATGAATTTAAAAAATTCAAAAC
AGTTGAAACTCCAGGAGGATCAGATATTTCTGTTACAGAAGCAATTTCAAGCGGTGCAGTAAGTACTTCTCATGCATTGG
ATGCTAAATTAATTGTATGTTGGACAAAAACTGGTAGAGCACCAAGAATGATTAGAAAATATGGACCAACTATACCAATT
ATTGCTTTGACAGACAATGACCAAACTGCAAGACAATTGGCATTAGTAAGAGGAGTTAGAGCTTACGTAGCAAAAGGATT
GGATAAAACAGATGATTTCTTCGCAAAAGCAAGAGAAATTGCAGCTAACCATGAAGAAGCGAACAAAGGTGATTTAGTAG
TAATGGTAACTGGAATCTCTAAAGAAGGAACAACTAACACATTCAGAGTAGAAAGAGTTGGAGAATAA

Protein sequence :
MKIKMTKVVCTIGPKTESIEMLTKLVESGMNVMRLNFSHGDFEEHGQRIKNIREVMKKTGKEIGILLDTKGPEIRTGKLE
GGKDVLLETGKKVTITTDYSFVGNAEKFAVSYPGIVDDLYEGTTVLLDDGLVGLKVESVDKAAGEVHCVITNTGELGETK
GVNLPDVSVGLPALAEKDIADLKFGCEQGVDFVAASFIRKASDVAEVRKVLDDNGGKNIQIIPKIESQEGVDNFDEILEL
SDGIMVARGDLGVEVPAEEVPFMQKMMIRKCNKAGKPVITATQMLDSMIRNPRPTRAEAGDVANAILDGTDAVMLSGESA
KGKYPVEAVKMMATISKRTDEFKKFKTVETPGGSDISVTEAISSGAVSTSHALDAKLIVCWTKTGRAPRMIRKYGPTIPI
IALTDNDQTARQLALVRGVRAYVAKGLDKTDDFFAKAREIAANHEEANKGDLVVMVTGISKEGTTNTFRVERVGE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 2e-126 64
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 7e-127 64
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 7e-127 64
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 4e-126 64

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Lebu_0874 YP_003163773.1 pyruvate kinase VFG0479 Protein 3e-127 64