Gene Information

Name : Lebu_2052 (Lebu_2052)
Accession : YP_003164904.1
Strain : Leptotrichia buccalis DSM 1135
Genome accession: NC_013192
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1212
EC number : -
Position : 2178208 - 2178954 bp
Length : 747 bp
Strand : -
Note : CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS

DNA sequence :
ATGAAAATACTGGGAGTAATACCTGCAAGATATGCCTCCAGCAGATTTGAAGGAAAGCCTTTAAAAGAAATCGAAGGGCA
TCCAATGATTGAATGGGTTTACAAAAGGGCGAAAAATGCGGATATTGACGAACTTGTAGTAGCTACTGATGATAAAAGGA
TTTTTGATGCGGTAAAAAAATTTGGCGGGAATGTAGTTATGACTTCTGAAAACCACGAAAATGGAACTTCCAGAATAATA
GAAGTTATAAATAAGGATGAATATAAAAATTATGATTTTATAATAAATATTCAAGGGGACGAGCCTTTAATTGACATTGA
GTCAATTAACATTCTGGCAAATAATTATCGTAATGAAAAATCAGAAATTGTTACATTAAAACAGGAAATGAAATTACAAA
AGGATATTGAAAATCCAAATCATGTAAAAGTAATTACAGATTTTAACAATAATGCAATTTATTTCAGTCGTTCAGTAATT
CCATATGAAAGGAAGCCAGATAAAAATTTTAAATATTTCAAACATATTGGAATTTATGGATACACAGCTAAATTTTTGAA
TGAATTAAAAAATTTAAAAGAAGGAATTTTGGAAAAAATAGAATCGCTTGAGCAGCTTAGATTTATTGAAAATGGGTATA
AAATAAAAGTTCTTGAAACGGTATCAAATGTAATTGGAGTCGATACTGAAGAAGATTTGAAAGAAGTTATCGAATTTGTA
AAGAAAAAAGGAATAAAAATTGAATAA

Protein sequence :
MKILGVIPARYASSRFEGKPLKEIEGHPMIEWVYKRAKNADIDELVVATDDKRIFDAVKKFGGNVVMTSENHENGTSRII
EVINKDEYKNYDFIINIQGDEPLIDIESINILANNYRNEKSEIVTLKQEMKLQKDIENPNHVKVITDFNNNAIYFSRSVI
PYERKPDKNFKYFKHIGIYGYTAKFLNELKNLKEGILEKIESLEQLRFIENGYKIKVLETVSNVIGVDTEEDLKEVIEFV
KKKGIKIE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 2e-42 43
kpsU CAE85213.1 KpsU protein Virulence PAI V 536 Protein 3e-42 43
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 1e-42 43