Gene Information

Name : Jden_2248 (Jden_2248)
Accession : YP_003162186.1
Strain : Jonesia denitrificans DSM 20603
Genome accession: NC_013174
Putative virulence/resistance : Unknown
Product : N-6 DNA methylase
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG0286
EC number : -
Position : 2436676 - 2438241 bp
Length : 1566 bp
Strand : +
Note : PFAM: N-6 DNA methylase; KEGG: afr:AFE_2793 type I restriction-modification system, M subunit

DNA sequence :
ATGGCACGCGCCGCGAAGCCGAAACCGACGAAGACACTCGAGCAGACCCTCTGGGAAGCTGCAGACAAGCTGCGCGGCAA
CCAGGAGCCGAGCGAGTACAAGCATGTCGTGCTCGGCCTGGTGTTCCTCAAGTACATCTCCGATCGCTTCGAGGAGCGAC
GTGCGACGCTCGAGGCAGAGCTTGCTGCGGAGGGCATCAAGCCGGAGCGACTGCCGGACTTCCTCGAAGACCGCGACGAA
TACACCAGTCACAACGTGTTCTGGGTGCCGGAGCTGGCGCGCTGGGGCTACATCCAGTCGGTCGCGAAGCAGCCCGAGAT
CGGGCAACAGATCGACCAGGCGATGGATCTCATCGAGAAGGAGAACCCAACGCTAAGGGGTGTGCTGCCACGCAACTATG
GACGCGATGGCCTCGACAAGCGCCGTCTGGGCGAGCTGGTAGACCTGATCGGCTCCATCGGGTTCACCGAGACCGACGAC
CACGGTGCCGACGACGTGCTGGGCCGGGTGTACGAGTACTTCCTCGGTCAGTTCGCCGGCAAGGAGACCGGCAAAGACGC
CGGAGCGTTCTACACGCCGCGTTCGGTAGTCAAGACGCTGGTCGAGATGCTGGAGCCCTACCAGGGGCGCGTCTATGACC
CTGCGGCGGGTTCCGGCGGCATGTTTGTGCAGTCGGCTGAGTTCGTGAAAGCTCACGGCGGCAAGCGCACCGACATCTCC
GTCTACGGGCAGGAGTTCACGGACACGACCTGGAAGCTCTCCAAGATGAACCTCGCACTGCGAGGTATCGAAGCCGACAT
GGGGCCGCGTTCGGCTGACTCATTCACCGATGACCTGCACCCGGATCTGCGGGCCGACTTCGTGATTGCCAACCCTCCGT
TCAACGTCTCTGACTGGTGGGATGCGAAGCTCGAGGGCGACCCGCGCTGGCAGTACGGCACCCCGCCGCAGGGCAACGCG
AACTTTGCGTGGGTGCAGCACTTCATCTACCACTTGAGCCCGAAGGGCACGGCGGGGTTCGTGCTTGCGAACGGATCCCT
GTCGTCGAAGAGCGGTGGTGAGGGCGAGATGCGTCGCAAGCTTGTCGAGGCCGACCTGGTCGACTGCATCGTGGCGATGC
CCGACAAGCTGTTCTTCAACACCGGCATCCCCGTCGCGCTCTGGTTCGTCTCCAAGGCCCGGCACGGCAACGGGCACCGC
GAACGCCGCAGCGAGGTGCTCTTCATCGACGCCCGAAAGCTCGGCACGATGGAGTCACGCCGTCTGCGCGTGCTGACGGA
CGACGACATCGCGAAGATTGCCGATACCTACCACGCCTGGCGCAACCACGACGGAGGCTACGAGGACGTGCCGGGCTTCG
CGAAGGCCGCCTCACTAGAAGAGATTGCCAAGCACGACTACGTGCTCACCCCAGGCCGCTACGTCGGCGCTGCCGAGGCT
GAGGTTGACGACGAGCCGATCGACGAGAAGATCGAGCGATTGACGAAGGAGCTGTTCGCCGAGTTCGAGCGCGGGCGCGA
GCTGGAGGATGAAGTGCGACAGCGTTTGAGTGGGGTGCAGCCGTGA

Protein sequence :
MARAAKPKPTKTLEQTLWEAADKLRGNQEPSEYKHVVLGLVFLKYISDRFEERRATLEAELAAEGIKPERLPDFLEDRDE
YTSHNVFWVPELARWGYIQSVAKQPEIGQQIDQAMDLIEKENPTLRGVLPRNYGRDGLDKRRLGELVDLIGSIGFTETDD
HGADDVLGRVYEYFLGQFAGKETGKDAGAFYTPRSVVKTLVEMLEPYQGRVYDPAAGSGGMFVQSAEFVKAHGGKRTDIS
VYGQEFTDTTWKLSKMNLALRGIEADMGPRSADSFTDDLHPDLRADFVIANPPFNVSDWWDAKLEGDPRWQYGTPPQGNA
NFAWVQHFIYHLSPKGTAGFVLANGSLSSKSGGEGEMRRKLVEADLVDCIVAMPDKLFFNTGIPVALWFVSKARHGNGHR
ERRSEVLFIDARKLGTMESRRLRVLTDDDIAKIADTYHAWRNHDGGYEDVPGFAKAASLEEIAKHDYVLTPGRYVGAAEA
EVDDEPIDEKIERLTKELFAEFERGRELEDEVRQRLSGVQP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hsdM YP_251979.1 type I restriction-modification system DNA methylase Not tested SCCmec Protein 4e-141 55
hsdM BAH57701.1 type I restriction-modification system DNA methylase Not tested Type-VII SCCmec Protein 3e-141 55
hsdM BAD24842.1 HsdM protein Not tested Type-V SCCmec Protein 6e-140 54
api49 CAF28523.1 putative HsdM-like N-methyl transferase Not tested YAPI Protein 4e-118 50