Gene Information

Name : Jden_1221 (Jden_1221)
Accession : YP_003161180.1
Strain : Jonesia denitrificans DSM 20603
Genome accession: NC_013174
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 1304219 - 1305637 bp
Length : 1419 bp
Strand : +
Note : KEGG: mxa:MXAN_6299 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta

DNA sequence : 
ATGCGCAAAGCAAAGATCGTTTGCACCATCGGACCCGCAACTTCTTCCCCGGAAAACATGCTTCGGCTTGTGAACGCCGG
CATGGATGTGGCACGTATTAACCGTAGCCACGGTGGGTACGAAGAACACGAGGCTGTTTACCGGAACATCCGGGCAGCAG
CTGAAGAGGCCGGGCGTAACGTCGCGGTTCTCGTTGACCTGCAAGGACCAAAGATTCGTCTGGGCAAGTTCGAGGAAGAC
CGCAAGTACTTCCTTGAGGTGGGCGACATTTTCACGATCACCACTGACGACATCCTTGGCAACCAGGAGATCTGCTCCAC
CACCCACAAGGGTCTTCCTCAGGATGCACGTGTTGGTGACCCTATCCTCATCGATGACGGTAAAGTCACCGTCCGGGTCA
TTGAGGTTGAGGGCAACAAAGTTGTCACCAAGTGTGAAGTTCCTGGCCCGCTGTCCAACAACAAGGGTTTGAACCTTCCT
GGTGTGGCTGTTTCTGTACCAGCCATGTCAGACAAGGACGAAGATGACCTTCGTTGGGCGATCCGCTTGGGTGCTGACAT
CATCGCTTTGTCATTTGTGCGCAGTGCACGTGACTACGATGACGTGCGCAAGGTCATGGAAGAAGAAGGACGTATCCTTC
CTGTTGTGGCGAAGGTTGAAAAGCCACAGGCCGTTGACAACCTCGCTGAGATTGTTGATGCGTTTGACGCCATCATGGTT
GCCCGCGGTGACCTTGGTGTGGAACTTCCTTTGGAACAGGTTCCACTCGTCCAAAAGCGTGCTGTTGAGCTTGCCCGCCG
GGCAGCAAAGCCTGTCATTGTGGCCACCCAGGTCCTTGAGTCAATGATTAGCTCACCTCGCCCCACCCGTGCAGAAGCCT
CTGACTGTGCAAACGCCATCCTTGATGGTGCTGACGCTGTGATGCTCTCGGGCGAAACATCAGTGGGTGACTTCCCCATT
GAGGCCGTTGAGACCATGGCGAAGATCGTGGAGGCCACCGAAGAACTTGGCCGTGAACGAATCGCGCCCTTGGGGTCAAC
CCCACACACCCGTGGTGGAGCTATCACTCGGGCGGCCGCTGAAATCGGCGAAACCCTTGGTGTGAAGTACATTGTGACCT
TTACTCAGTCAGGTGACTCCGCACGTCGTTTCGCACGACTGCGCTCACCATTGCAGCACCTTGCATTCACCCCACGTTCT
GACGTGCGTTCCGTTCTTGCCCTGTCATGGGGGGTCACCTCGCGCCAGGTTGACCAGGTGGAATCAACTGATGCGATGGT
TCGTCAAGTAGACGCGAAACTCCAAGAAGACGGTCTCGCTGAATCAGGCGATCTCGTCGTTGTTGTCTCCGGTGCCCCTG
TTGGGGTCTCTGGGACCACGAACTCGATTCTCGTGCACCGCATCGGTGACGACATCTAG

Protein sequence : 
MRKAKIVCTIGPATSSPENMLRLVNAGMDVARINRSHGGYEEHEAVYRNIRAAAEEAGRNVAVLVDLQGPKIRLGKFEED
RKYFLEVGDIFTITTDDILGNQEICSTTHKGLPQDARVGDPILIDDGKVTVRVIEVEGNKVVTKCEVPGPLSNNKGLNLP
GVAVSVPAMSDKDEDDLRWAIRLGADIIALSFVRSARDYDDVRKVMEEEGRILPVVAKVEKPQAVDNLAEIVDAFDAIMV
ARGDLGVELPLEQVPLVQKRAVELARRAAKPVIVATQVLESMISSPRPTRAEASDCANAILDGADAVMLSGETSVGDFPI
EAVETMAKIVEATEELGRERIAPLGSTPHTRGGAITRAAAEIGETLGVKYIVTFTQSGDSARRFARLRSPLQHLAFTPRS
DVRSVLALSWGVTSRQVDQVESTDAMVRQVDAKLQEDGLAESGDLVVVVSGAPVGVSGTTNSILVHRIGDDI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 7e-75 44
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 4e-75 44
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 4e-75 44
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 1e-74 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Jden_1221 YP_003161180.1 pyruvate kinase VFG0479 Protein 2e-75 44